HOME >> BIOLOGY >> NEWS
The building blocks of erection: Nitric oxide...and more nitric oxide

A team of Hopkins scientists has greatly advanced the science of penile erection, showing for the first time the mechanism for continued production of nitric oxide that maintains an erection over time. The findings are published in the March 19 issue of the Proceedings of the National Academy of Sciences.

"The physiology of erection is like driving a car," says Arthur Burnett, M.D., associate professor of urology at Hopkins and senior author of the study. "You can't just turn the key and expect to go anywhere. You also need to hit and hold the accelerator."

Researchers at Hopkins ten years ago discovered that release of nitric oxide from nerve endings in the penis caused erection, but the temporary release of nitric oxide a neurotransmitter that survives just a few seconds before breaking down couldn't explain how erections are naturally sustained over time.

Working with rats and genetically transformed mice, Hopkins scientists found that after an initial burst of nitric oxide from nerve endings triggers erection, blood vessels release more nitric oxide to harden and maintain the erection.

"Once blood starts flowing into the penis, the source of nitric oxide in the blood vessels is continuously activated so that more nitric oxide is released, more tissue relaxes, more blood comes in and a sustained erection is achieved," Burnett says.

This cascade of events, Burnett says, begins when erotic thoughts or physical sensations produce nitric oxide release in nerve endings in the penis. Nitric oxide is a relaxant that allows blood vessels to open up or dilate, bringing increased blood flow and swelling of tissues. The flow of blood also creates a minor stress on the blood vessel wall which activates the release of more nitric oxide. This time it is from cells in the wall of the blood vessel the endothelial cells rather than from nerves. Endothelial nitric oxide causes more tissue to relax and the process repeats until
'"/>

Contact: Trent Stockton
tstockt1@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
18-Mar-2002


Page: 1 2

Related biology news :

1. Termites could hold the key to self-sufficient buildings
2. Environmental costs of home construction lower with wise choice, reuse of building materials
3. Researchers show how to assemble building blocks for nanotechnology
4. Embryonic stem cell therapy shows steady benefits in rebuilding infarcted heart
5. Near-zero-energy buildings blessing to owners, environment
6. RNA could form building blocks for nanomachines
7. Indoor mold, building dampness linked to respiratory problems and require better prevention
8. New IU Bloomington life sciences building gets a name
9. Purdue chemists put the twist on protein building block
10. Destructive wizardry of Ozz-E3 ligase appears key to building skeletal muscles in embryos and adults
11. Swimming can contribute to rebuilding bone strength

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... 2017 Today HYPR Corp. , leading ... component of the HYPR platform is officially FIDO® ... security architecture that empowers biometric authentication across Fortune 500 ... secured over 15 million users across the financial services ... home product suites and physical access represent a growing ...
(Date:3/30/2017)... , March 30, 2017 The research ... system for three-dimensional (3D) fingerprint identification by adopting ground breaking 3D ... a new realm of speed and accuracy for use in identification, ... an affordable cost. ... ...
(Date:3/24/2017)... The Controller General of Immigration from Maldives Mr. ... have received the prestigious international IAIR Award for the most innovative ... ... Maldives Immigration ... Algeen (small picture on the right) have received the IAIR award for ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... AMRI, a global contract ... to improve patient outcomes and quality of life, will now be offering its ... attributed to new regulatory requirements for all new drug products, including the finalization ...
(Date:10/11/2017)... ... 2017 , ... Personal eye wash is a basic first aid supply for any work environment, ... eye do you rinse first if a dangerous substance enters both eyes? It’s one less ... with its unique dual eye piece. , “Whether its dirt and debris, or an acid ...
(Date:10/11/2017)... LAGUNA HILLS, Calif. , Oct. 11, 2017 ... London (ICR) and University of ... prognostic tool to risk-stratify patients with multiple myeloma (MM), in ... nine . The University of Leeds ... by Myeloma UK, and ICR will perform the testing services ...
(Date:10/10/2017)... SAN DIEGO, CALIF. (PRWEB) , ... October 10, 2017 , ... ... website as part of its corporate rebranding initiative announced today. The bold new ... broaden its reach, as the company moves into a significant growth period. , It ...
Breaking Biology Technology:
Cached News: