The next generation of scientists recognized at Johns Hopkins

revealed for the first time how cells get rid of messenger-RNA that has no "stop" signal. Understanding this clean-up mechanism may help efforts to treat many genetic diseases that are caused by mutation or misreading of stop sequences in DNA, she says.

The first Nupur Thekdi Research Award, named for an M.D./Ph.D. student who died accidentally in 2001, recognizes M.D./Ph.D. candidate Jacob Jones, whose research has changed thinking about the proteins that make membranes of a tiny compartment within cells. The Daniel Nathans Research Award went to Mark Levis, M.D., Ph.D., whose studies have led to clinical trials of a new treatment for acute myelogenous leukemia, the disease that claimed the life of the award's namesake, a Nobel laureate and Hopkins professor.

Awards also are made for clinical research. Postdoctoral fellow Lisa Korn, M.D., discovered that screening for osteoporosis in people over age 65 may be beneficial, while cardiology fellow Charles Henrikson, M.D., M.P.H., revealed that nitroglycerin's effect on chest pain does not help diagnosis, contrary to conventional wisdom. Korn received the Helen B. Taussig Research Award and Henrikson the Alfred Blalock Research Award.

For detailed information about all of this year's awardees, visit http://www.hopkinsmedicine.org/press/APRIL/YIDrecipients.html.


Contact: Joanna Downer
Johns Hopkins Medical Institutions

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