Thimerosal, found in childhood vaccines, can increase the risk of autism-like damage in mice

  • Significant abnormalities in brain architecture, affecting areas subserving emotion and cognition;
  • Increased brain size.

    These findings have relevance for identification of autism cases relating to environmental factors; design of treatment strategies; and development of rational immunization programs. The use of thimerosal in vaccines has been reduced over the past few years, although it is still present in some influenza vaccines. Identifying the connection between genetic susceptibility and an environmental trigger for autism--in this case thimerosal exposure--is important because it may promote discovery of effective interventions for and limit exposure in a specific population, stated the lead author Dr. Mady Hornig. Because the developing brain can be exposed to toxins that are long gone by the time symptoms appear, clues gathered in these animal models can then be evaluated through prospective human birth cohorts--providing a powerful to tool to dissect the interaction between genes and the environment over time.


  • Contact: Julio Licinio
    Molecular Psychiatry

    Page: 1 2

    Related biology news :

    1. New signs of life found at the Poles
    2. Key cell-death step found
    3. European common frog found to use novel mating strategy
    4. Byproduct of water-disinfection process found to be highly toxic
    5. Genuine stem cells found in skin might treat hair loss, wounds
    6. Flame retardants found on supermarket shelves
    7. Anti-cancer compound in vegetables found to block late-stage breast-cancer cell growth
    8. Genetic clues found for common congenital brain disorder
    9. New clues to hereditary blinding disease found
    10. Anti-bacterial additive found in Maryland streams
    11. Genetic mutation linked to more aggressive breast cancer found more often in African-Americans

    Post Your Comments:

    (Date:1/14/2019)... ... January 14, 2019 , ... CellMax ... cancer cells in blood, will present new findings at the ASCO Gastrointestinal Cancer ... colorectal cancer. The results from this study show CellMax Life’s blood test, based ...
    (Date:1/10/2019)... (PRWEB) , ... January 09, 2019 , ... Dr. Beanlands ... Heart Institute in Ottawa, Ontario, Canada. He is also Director of its National ... of Medicine, in the Department of Radiology, and in the Department of Cellular and ...
    (Date:1/10/2019)... ... 2019 , ... A major goal for pharmaceutical companies has ... significantly more expensive in vivo studies in order to reduce costs and improve ... researchers have begun to adopt 3D cell culture models which have been shown ...
    Breaking Biology News(10 mins):
    (Date:12/20/2018)... ... December 20, 2018 , ... New Year’s brings reflection ... changes in regulations in the European Union (EU) on the horizon, Jim Kasic, president ... , “The transition to the EU Medical Device Regulation (MDR), digital health, and big ...
    (Date:12/18/2018)... ... December 18, 2018 , ... Patients with early stages of breast cancer who ... post-treatment versus whole breast irradiation, a new study suggests. , Patients with early stage ... irradiation after removal of the cancerous tumor because there is a 30 to 40 ...
    (Date:12/13/2018)... ... December 13, 2018 , ... Microbial Discovery Group LLC (MDG) ... been part of their strategic plan and an important milestone in increasing their ... opportunities for MDG within the $44 Billion human probiotic market. This plan is ...
    (Date:12/5/2018)... (PRWEB) , ... December 04, ... ... an established North American full-service contract research organization (CRO), announced the acquisition ... transaction significantly strengthens ARG’s reach and experience in the management of clinical ...
    Breaking Biology Technology:
    Cached News: