HOME >> BIOLOGY >> NEWS
Third Wave scientists publish advance in gene expression monitoring with revolutionary RNA Invader Assay

MADISON, Wis. July 2, 2001 Scientists at Third Wave Technologies Inc. (Nasdaq: TWTI) have validated a technological breakthrough with the potential to revolutionize the analysis of gene expression for research and clinical applications including genome research, drug development and disease monitoring.

Third Waves Invader technology is capable of identifying and quantitating low levels of unique RNAs directly from total RNA or crude cell samples called cell lysates, according to findings published in the July issue of Nature Biotechnology. Direct detection of gene expression levels with Invader technology eliminates several costly, time-consuming steps required by other technologies and minimizes the risk of sample contamination.

"The ability to analyze for RNA easily and directly, without complicated procedures that can contaminate the sample, is a significant advance in RNA detection technology and the efforts to understand diseases and develop drugs to treat them," said Lance Fors, Ph.D., president and chief executive officer of Third Wave Technologies.

Key Findings Reported in Nature Biotechnology: RNA Invader Assay

  • Direct Detection. The RNA Invader assay enables identification and quantitation directly from total RNA or crude cell lysate samples prepared using a simple and inexpensive process. Many RNA tests require high-purity RNA purification, often in combination with time-consuming and expensive multi-step preparation of the RNA samples before they can be tested. A method known as RT-PCR is among the most commonly used. It includes RNA purification, transcription of the RNA to its DNA complement and creation of additional copies of the DNA again and again prior to detection. RT-PCR methods are inherently less accurate than direct RNA detection and test results can be skewed by sample contamination.
  • Accuracy and Precision. The RNA Invader assay is capable of detecting changes in gene expression levels as
    '"/>


Contact: Beth Preston
epreston@fkhealth.com
617-761-6739
Feinstein Kean Healthcare
2-Jul-2001


Page: 1 2 3

Related biology news :

1. Popular Science announces Third Annual Brilliant 10
2. Third set of awards are announced under interagency biodiversity program
3. Large brains not required? Third and smallest skull of first Eurasians reported in Science
4. Rutgers scientists create high-protein corn with Third World potential
5. Third piece completes deadly puzzle: Structure of anthrax toxin offers clues to treatment
6. University Of Kentucky Researcher Awarded MERIT Extension For Study Of Third World Killer
7. Third Annual Awards For Presidential Green Chemistry Challenge Recognize Innovations
8. Fortified Drink Improves Third World Nutrition
9. DNA lends scientists a hand, revealing new chemical reactions
10. Conference at UH opens doors for new scientists, engineers
11. Wisconsin scientists develop quick botox test

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/12/2019)... ... November 12, 2019 , ... G5, the ... digital advertising performance up to 25% and reduces cost-per-click by as much as ... advanced multi-touch attribution (MTA) to predict best advertising outcomes and automatically allocate daily ...
(Date:11/12/2019)... ... November 12, 2019 , ... Atlantic Ultraviolet Corporation (AUV), ... that distributors voted their patented automatic and manual wipers the #1 best feature ... most frequent maintenance task required of an ultraviolet water purifier is quartz sleeve ...
(Date:11/9/2019)... ... ... SiteSeer Technologies, creator of SiteSeer Professional retail site selection software, is pleased ... The boutique real estate developer of single and multi-tenant buildings on sites ranging from ... analysis of markets. , Geoffrey Kerth, manager of GPK Acquisitions, says that his ...
Breaking Biology News(10 mins):
(Date:11/9/2019)... ... November 08, 2019 , ... ... technology for use in pathology research, today announced the results of analyses ... patients enrolled in the phase 3 selonsertib studies (STELLAR). Strong correlations were ...
(Date:11/5/2019)... ... November 04, 2019 , ... ... technologies, development, and manufacturing solutions for drugs, biologics, gene therapies, and consumer ... technology, GPEx® Boost. The technology enhances Catalent’s proven GPEx expression platform through ...
(Date:11/2/2019)... TORONTO (PRWEB) , ... October 31, 2019 , ... ... are not always used to communicating with each other: study managers, principal investigators, ... cause misunderstandings if a party is not informed of the latest data, potentially ...
(Date:10/30/2019)... ... October 30, 2019 , ... While using cold plasma to kill cancer ... South Dakota School of Mines & Technology are exploring new ways to regulate ... , If successful, the technique would prove to be a drug-free, minimally invasive ...
Breaking Biology Technology:
Cached News: