HOME >> BIOLOGY >> NEWS
Three genes linked to psoriasis susceptibility identified on chromosome 17

Portland, Ore., Nov. 9, 2003 Researchers using data gleaned from a tissue bank created by the National Psoriasis Foundation have identified three of the first genes associated with psoriasis. The finding, published in the December 2003 issue of the prestigious journal Nature Genetics, marks a significant advance in the understanding of psoriasis, an immune-mediated disease with both genetic and environmental triggers, and may lead to new treatments for the disease.

"This is an exciting breakthrough that opens a new chapter in our quest to unlock the secrets of psoriasis," said Gail Zimmerman, president and CEO of the National Psoriasis Foundation. "We are clearly making great progress in understanding the complex genetic underpinnings of this often debilitating disease."

Anne M. Bowcock, Ph.D., of Washington University in St. Louis, and her colleagues identified three genes on chromosome 17 in which the "on and off" switches are impaired in statistically significant numbers of psoriasis patients. Several other psoriasis susceptibility genes are expected to be identified in the months and years ahead, including one on chromosome 6. In all, it is suspected that more than a dozen genes are involved in psoriasis.

"Over the next few years, researchers are going to identify a large number of psoriasis susceptibility genes," Dr. Bowcock said. "These will be important building blocks toward finding a cure in the future. In the meantime, the findings could help pharmaceutical and biotechnology companies craft the next generation of medications to treat the disease, and ultimately lead to more successful management of psoriasis."

This scientific research was made possible by the efforts of the Psoriasis Foundation, which created the National Psoriasis Tissue Bank and opened it in 1994 with money donated by Foundation members. This tissue bank, built with blood samples from hundreds of families with psoriasis, provided the raw material that the
'"/>

Contact: Michael Paranzino
mike@psoriasis.org
503-546-8393
National Psoriasis Foundation
9-Nov-2003


Page: 1 2

Related biology news :

1. Three new South American fish identified
2. Three personal ads for physics
3. Three molecular-targeted compounds show promise against cancers
4. Three Pacific Northwest National Laboratory inventions win R&D 100 Awards
5. Three Gorges Dam is an opportunity for ecoscience
6. Three tourist experiences named best worldwide for environmental, social responsibility
7. Three inferior prefrontal regions of the brain found receptive to somatosensory stimuli
8. Three dimensional structure of a protein transport machine
9. Three studies released this week shed new light on eating nuts for good health
10. Three nations agree to share ice core thatmay yield clues about nature of Lake Vostok
11. Three-D images shed light on first steps of RNA synthesis

Post Your Comments:
(Date:7/7/2015)... July 7, 2015  Based on its recent ... Sullivan recognizes Credence ID, LLC with the 2015 ... of the Year Award. Credence ID has developed ... its mission of offering enrollment and identification solutions ... Credence ID was formed by experts from the ...
(Date:7/2/2015)... 2015 Fingerprint Cards has received an ... FPC1155 from the distributor World Peace Industrial Group (WPI), part ... Asia . Deliveries are planned to take ... used by smartphone manufacturers in Asia . ... communicated revenue guidance of approximately 2,200 MSEK for 2015. ...
(Date:6/26/2015)... 26, 2015 ATL Technology, LLC, a top provider ... in single use solutions, headquartered in Springville, Utah ... California corporation with locations in ... Jose, Costa Rica ). This acquisition will ... with ATL Technology,s existing facility in Costa ...
Breaking Biology News(10 mins):Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2ATL Technology Announces Acquisition of MedConx, Inc. and Expanded Global Footprint 2
(Date:7/28/2015)... ZIONA, Israel , ... Ltd. (TASE:CLPT; OTC:CQPTY), a regenerative medicine company utilizing ... products, today announced that Shomrat Shurtz has been ... 20, 2015.      (Photo: http://photos.prnewswire.com/prnh/20150728/246955 ... over 25 years of experience in marketing, regulatory ...
(Date:7/27/2015)... ... July 27, 2015 , ... This is a professional and ... basic overview of the industry including definitions, classifications, applications and industry chain structure. ... competitive landscape analysis, and key regions development status. Development policies and plans are ...
(Date:7/27/2015)... ... 2015 , ... BlueInGreen® announced the addition of EnviroSales of ... world’s most efficient gas dissolution technology to all of Florida, excluding the panhandle. ... and municipal markets. With offices located in Sarasota, Sebring and Melbourne Beach, the ...
(Date:7/27/2015)... ... July 27, 2015 , ... Visual Assay was named as a ... 100 most innovative technologies and services of the past year. More than 70 judges ... category. The winners will be announced at the 2015 R&D 100 Awards Dinner on ...
Breaking Biology Technology:CollPlant Names Shomrat Shurtz Senior Director of Business Development 22015 Biophotonics Market Global Research 22015 Biophotonics Market Global Research 3BlueInGreen Brings Water Treatment Technology to Florida 2Visual Assay® Named Finalist in 53rd Annual R&D 100 Awards 2
Cached News: