Tiny RNAs-'biological equivalent of dark matter'-wins prestigious AAAS Newcomb Cleveland Prize

The discovery of micro-sized RNA molecules (miRNAs)-a breakthrough described as "the biological equivalent of dark matter, all around us but almost escaping detection"-earned the coveted 2001-2002 AAAS Newcomb Cleveland Prize.

Three journal reports, published in the 26 October 2001 issue of Science, were named to receive the Prize, the oldest award conferred by the American Association for the Advancement of Science (AAAS). The AAAS Newcomb Cleveland Prize was established in 1923, with funds donated by Newcomb Cleveland of New York City, to recognize outstanding Science articles.

The award-winning research provides new insights into gene expression-the fundamental process by which information in life's blueprint, DNA, is transferred to messenger RNA (mRNA) and then translated into proteins. Understanding how protein production is controlled during gene expression is essential to unraveling the mysteries of all life processes, including, for example, the development of disease.

The AAAS Newcomb Cleveland Prize was awarded to three research teams at the Dartmouth Medical School in Hanover, New Hampshire; the Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology in Cambridge, Massachusetts; and Germany's Max Planck Institute for Biophysical Chemistry.

Together, the winning articles "reveal the completely unexpected abundance of ultra-small RNA molecules, only 20 to 24 nucleotides long," explained Donald Kennedy Editor-in-Chief of Science. "What we've learned is that these abundant microRNAs are evolutionarily conserved across a number of organisms, and may affect gene regulation involved in the development of many types of cells and tissues. The outstanding contributions of these three research teams have thus written a new chapter in our understanding of gene control, and are arguably among the most significant biomedical research papers published in 2001."

In studies of the worm, C. elegans, for


Page: 1 2 3

Related biology news :

1. New lower-cost assay system equivalent to flow cytometry for accurate CD4+/CD8+ cell counts
2. The ecological equivalent of Ellis Island: from ancestry to biodiversity
3. Gladstone investigator Mike McCune wins prestigious NIH Directors Pioneer Award
4. Carnegie Mellon computational biologist Russell Schwartz receives prestigious CAREER award
5. Brown earns prestigious geography award
6. Ohio State wetlands professor wins prestigious Water Prize
7. Top US scientist honored with prestigious award
8. Dr. Walter Reich, Ph.D., receives prestigious AAAS 2003 Scientific Freedom and Responsibility Award
9. John Allen Paulos receives prestigious AAAS Award for Public Understanding of S&T
10. UT Southwestern scientist awarded prestigious American Cancer Society research professorship
11. Field Museum gives prestigious Parker Gentry Award to Tanzanian anti-poaching activist

Post Your Comments:
(Date:9/30/2015)... Calif. , Sept. 30, 2015  With nearly ... the number of new SCIs estimated to reach 12,500 ... Southern California Resource Services for Independent Living ... ILCs in California opening doors ... range of programs and services, notably assistive technology services ...
(Date:9/29/2015)... SUNNYVALE, Calif. , Sept. 29, 2015 ... technology improves employee productivity while also saving energy ... features such as Low Power Active Mode and embedded ... workplace transformation Fujitsu today shows that ... of new and refreshed models to its enterprise desktop ...
(Date:9/28/2015)... Sept. 28, 2015  The monitoring of vital ... body temperature, is an essential component of patient ... of deterioration in a patient,s condition. However, in ... are typically taken during routine observation rounds only ... patient deteriorates between these observation rounds, the warning ...
Breaking Biology News(10 mins):
(Date:10/8/2015)... ... 08, 2015 , ... Cystic fibrosis (CF) is a genetic ... and results in dysfunction of the lungs and the gastrointestinal (GI) tract. In ... is very difficult to clear, blocks the airways and the glands, and creates ...
(Date:10/7/2015)... ... 07, 2015 , ... Neil Riordan, PhD to Discuss Medicinal Effects of Mesenchymal ... Mar-a-Lago from 3:50 pm to 4:30 pm. , Dr. Riordan is one of the ... He is the Co-Founder and Chief Science Officer of the Riordan-McKenna Institute ...
(Date:10/7/2015)... 2015  ContraVir Pharmaceuticals, Inc. (Nasdaq: CTRV ) ... the development and commercialization of targeted antiviral therapies, today ... 5,000,000 shares of its common stock and warrants to ... stock at a fixed combined price to the public ... will be issued separately.  The warrants will be exercisable ...
(Date:10/7/2015)... Pa. , Oct. 7, 2015   VWR ... independent provider of laboratory products, services and solutions, ... Inc. (PTI), a specialty solvent company that performs ... This acquisition will enhance VWR,s growing laboratory and ... laboratory and biopharmaceutical manufacturing customers. Manuel ...
Breaking Biology Technology:
Cached News: