HOME >> BIOLOGY >> NEWS
Tiny tango: Device sorts microscopic particles with speed and precision

In a remarkable collaboration between engineers, physicists and biologists, Princeton scientists have invented a device that rapidly sorts microscopic particles into extremely fine gradations of sizes, opening a range of potential uses.

The researchers have used the device to sort particles ranging in size from bacterial cells to large segments of DNA and reported their results in the May 14 issue of Science. The technology could greatly accelerate the work of sequencing genomes and could find uses in many other areas, from improving the performance of pharmaceuticals to detecting bioterrorism agents.

Until now there was no way to sort large quantities of molecules or cells by size with such speed and precision, according to the researchers. Current methods separate particles only according to major differences in size and, for particles such as DNA, can take hours to perform. The Princeton invention can distinguish large quantities of particles that are 1.00 micrometer (a millionth of a meter) from others that are 1.005 microns in a matter of seconds.

The device is dubbed a "tango array" for the precise choreography it imposes upon particles.

The discovery was led by Lotien R. Huang, a postdoctoral researcher in electrical engineering, and grew out of a long-term collaboration between James Sturm, professor of electrical engineering, Robert Austin, a professor of physics, and Edward Cox, a professor of molecular biology, all of whom are co-authors of the Science paper. The group, which is part of the newly formed Princeton Institute for the Science and Technology of Materials, has produced a variety of devices for sorting DNA and other particles, but none as fast and precise as the tango array.

The trade-off between speed and precision had seemed insurmountable, said Huang, who has been building and testing sorting devices for nearly six years. The breakthrough came when a c
'"/>

Contact: Patty Allen
pallen@princeton.edu
609-258-6108
Princeton University
4-Jun-2004


Page: 1 2 3 4

Related biology news :

1. Device that rapidly detects nerve agents named one of greatest army inventions for 2003
2. Device detects, traps and deactivates airborne viruses and bacteria
3. Device liberates quadriplegic from ventilator
4. Growing Up On Their Own: Smart Plastics Organize Themselves Into Useful Optical Devices
5. New Rehabilitative Device Combines Form And Function For Children With Mobility Impairments
6. New Device Brightens Recycling Efforts
7. New Device To Alleviate Distress Caused By Tinnitus
8. University of Kentucky Neuroscientist Develops Unique Device For Treatment Of Brain Tumors
9. Penn Researchers Invent Worlds First Device To Rapidly Assess Lung Function
10. Circulatory Device -- A Bridge To Recovery For Heart Failure?
11. UPMC Reports On New Liver Assist Device

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/16/2017)... , May 16, 2017   Bridge ... health organizations, and MD EMR Systems , ... development partner for GE, have established a partnership ... Portal product and the GE Centricity™ products, including ... EMR. These new integrations will ...
(Date:4/17/2017)... 17, 2017 NXT-ID, Inc. (NASDAQ: NXTD ... filing of its 2016 Annual Report on Form 10-K on Thursday ... ... available in the Investor Relations section of the Company,s website at ... website at http://www.sec.gov . 2016 Year Highlights: ...
(Date:4/11/2017)... 2017 No two people are believed ... New York University Tandon School of Engineering and ... that partial similarities between prints are common enough ... phones and other electronic devices can be more ... lies in the fact that fingerprint-based authentication systems ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... For the second time in ... STEM Mentoring Award. Representatives of the FirstHand program travelled to Washington, D.C. Tuesday, ... , US2020’s mission is to change the trajectory of STEM education in America ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... business process optimization firm for the life sciences and healthcare industries, announces a ... in San Francisco. , The presentation, “Automating GxP Validation for Agile Cloud Platforms,” ...
(Date:10/9/2017)... N.C. (PRWEB) , ... October 09, 2017 , ... At ... announced Dr. Christopher Stubbs, a professor in Harvard University’s Departments of Physics and Astronomy, ... Stubbs was a member of the winning team for the 2015 Breakthrough Prize in ...
(Date:10/7/2017)... ... October 06, 2017 , ... Phase ... metagenome deconvolution product, featuring the first commercially available Hi-C kit. Researchers can ... Hi-C metagenome deconvolution using their own facilities, supplementing the company’s full-service ProxiMeta ...
Breaking Biology Technology:
Cached News: