Tips from the Journals of the American Society for Mi...( searchers. In the study the res...)

Tips from the Journals of the American Society for Microbiology

searchers.

In the study, the researchers genetically engineered tobacco and potato plants to produce a major structural protein of HPV. When the protein was purified and administered to mice, it induced an immune response. When the potatoes were fed to mice, they also induced an immune response, though not as significant.

"Here, we demonstrated as a first step that it is possible to produce transgenic plants expressing the HPV-16 L1 protein in a form appropriate for immunization purposes," say the researchers.

(S. Biemelt, U. Sonnewald, P. Galmbacher, L. Willmitzer, and M. Muller. 2003. Production of human papillomavirus type 15 virus-like particles in transgenic plants. Journal of Virology, 77: 9211-9220.)

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Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
15-Aug-2003

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