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Tips from the Journals of the American Society for Microbiology: August 2001

nce. The compound, known as microcin 24, is an antimicrobial peptide secreted by a strain of E. coli that causes urinary tract infections. Many bacteria produce microcins as a means of disabling and competing with nearby bacteria. In this study, the researchers were testing Salmonella to see if they developed resistance to microcin 24. Not only did they develop resistance to the microcin but also to multiple antibiotics.

"I appears that multidrug-resistant Salmonella can arise as a result of an insult from other pathogenic bacteria," say the researchers. "Microcin production gives an advantage to pathogenic E. coli while also potentially selecting for multidrug-resistant Salmonella."

(S.A. Carlson, T.S. Frana, and R.W. Griffith. 2001. Antibiotic resistance in Salmonella enterica serovar typhimurium exposed to microcin-producing Escherichia coli. Applied and Environmental Microbiology, 67: 3763-3766.)

Hepatitis C outbreak traced to gynecological surgery

Four women in Italy appear to have contracted the hepatitis C virus (HCV) while undergoing gynecological surgical procedures in the same operating room on the same day in 1998. This report, which illustrates the potential risk of HCV transmission in a surgical setting, appears in the August 2001 issue of the Journal of Clinical Microbiology.

"In March 1998 two women with recent HCV infection who had both undergone gynecological surgery on January 9, 1998, in the same operatin room were admitted to [the hospital]. An investigation was conducted to identify further cases, the likely source of infection and the route of transmission," say the researchers.

Researchers identified two additional women with acute HCV who had had surgery that day. Molecular testing of the virus suggests that all the infections came from a common source, which was identified as a woman known to have chronic HCV who had undergone surgery first that day. The mode of tra
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Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
7-Aug-2001


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