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Household disinfectant potential cause of antibiotic resistance

Researchers from Midwestern University in Illinois, Curtin University of Technology in Australia, and Illinois State University have found that when bacteria become resistant to pine oil cleaners (POC), a common household disinfectant, they may also be resistant to some antibiotics. Their findings appear in the November 2002 issue of Applied and Environmental Microbiology.

In the study, POC-resistant Staphylococcus aureus were found to also be resistant to the antibiotics, vancomycin and oxacillin. Further testing suggests that the same genetic mechanism may be responsible for both types of resistance.

"These results add to a growing body of reports suggesting that common disinfectants can select for bacteria with reduced susceptibilities to antibiotics," say the researchers.

(C.T.D. Price, V.K. Singh, R.K. Jayaswal, B.J. Wilkinson, J.E. Gustafson. 2002. Pine oil cleaner-resistant staphylococcus aureus: reduced susceptibility to vancomycin and oxacillin and involvement of SigB. Applied and Environmental Microbiology, 68. 11: 5417-5421.)

Bacterial infection possible cause of liver disease

A bacterial infection could be responsible for some cases of chronic liver disease, say researchers from Estonia and Sweden in the November 2002 issue of the journal Clinical and Diagnostic Laboratory Immunology.

In the study, researchers compared levels of antibodies against Helicobacter bacteria (the acid tolerant family of bacteria responsible for most peptic ulcers) in patients with chronic liver disease to a random sample from the general public. The patients with liver disease had significantly higher antibodies to at least two species of Helicobacter bacteria.

"Bile-tolerant Helicobacter species such as Helicobacter pullorum, Helicobacter bilis, and Helicobacter hepaticus are associated with hepatic disorders in animals an
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Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
11-Nov-2002


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