HOME >> BIOLOGY >> NEWS
Tips from the journals of the American Society for Microbiology

New Vaccine May Protect Against Cervical Cancer

Researchers from Maryland have developed a new DNA vaccine that targets proteins expressed in cervical cancer cells. Their findings appear in the August 2004 issue of the Journal of Virology.

Human papillomavirus (HPV) is found in more than 99 % of cervical cancer cases, which is the second leading cause of cancer death among women throughout the world. Consistently identified in HPV cancer cells, proteins E6 and E7 are the determined cause of malignant transformation.

In the study mice were immunized with a DNA vaccine encoding CRT (a binding protein with many cellular functions) and linked to E6 targeting HPV-associated lesions. Results showed a significant T-cell immune response specific to E6, indicating that a CRT/E6 DNA vaccine could also protect against E6 expressing tumors.

"We have shown that DNA vaccines encoding E6 can generate strong E6-specific CD8+ T-cell immunity and can control the growth of E6-expressing tumor cells," say the researchers. "Therefore, E6 vaccines, and perhaps E6 and E7 vaccines in combination, may represent an important approach to controlling HPV-associated cancers."

(S. Peng, H. Ji, C. Trimble, L. He, Y. Tsai, J. Yeatermeyer, D.A.K. Boyd, C. Hung, T.-C. Wu. 2004. Development of a DNA vaccine targeting human papillomavirus type 16 oncoprotein E6. Journal of Virology, 78. 16: 8468-8476.)


New Antimalarial Compound Identified Through Self-Medicative Behavior of Wild Chimps

French and Ugandan researchers have discovered novel antimalarial compounds by observing the behavior of wild chimps. Their findings appear in the August 2004 issue of the journal Antimicrobial Agents and Chemotherapy.

In the study researchers observed a Kanyawara community of fifty wild chimpanzees for unusual feeding behaviors, especially those of ill chimps. Stool and urine samples were collected for analysis. The occasiona
'"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
17-Aug-2004


Page: 1 2 3

Related biology news :

1. Select research highlights from current AACR journals
2. Open Access journals proven to compete on quality
3. Tips from the journals of the American Society for Microbiology
4. American Society of Plant Biologists offers developing nations free access to science journals
5. BioMed Central to deposit e-journals with the British Library
6. ASM journals tipsheet: May 2001
7. Tipsheet: April journals of the American Society for Microbiology
8. Tips from the journals of the American Society for Microbiology: February 2001
9. Highlights of the October 2004 Journal of the American Dietetic Association
10. The American Phytopathological Society announces 2004 awards
11. Tips from the Journals of the American Society for Microbiology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/24/2017)... 24, 2017 The Controller General of Immigration from ... Abdulla Algeen have received the prestigious international IAIR Award for the ... Continue Reading ... ... Controller Abdulla Algeen (small picture on the right) have received the IAIR ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based ... to 2022", published by MarketsandMarkets, the market is expected to be worth USD ... 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , Oct. ... Cancer Research, London (ICR) and University ... SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple myeloma ... MUK nine . The University of Leeds ... partly funded by Myeloma UK, and ICR will perform the ...
(Date:10/10/2017)... ... 2017 , ... San Diego-based team building and cooking events company, Lajollacooks4u, has ... The bold new look is part of a transformation to increase awareness, appeal to ... period. , It will also expand its service offering from its signature gourmet cooking ...
(Date:10/10/2017)... 10, 2017 International research firm Parks Associates announced ... at the TMA 2017 Annual Meeting , October 11 in ... residential home security market and how smart safety and security products impact ... Parks Associates: Smart Home ... "The residential security market has ...
(Date:10/9/2017)... DIEGO , Oct. 9, 2017  BioTech ... biological mechanism by which its ProCell stem cell ... critical limb ischemia.  The Company, demonstrated that treatment ... amount of limbs saved as compared to standard ... the molecule HGF resulted in reduction of therapeutic ...
Breaking Biology Technology:
Cached News: