HOME >> BIOLOGY >> NEWS
Tips from the journals of the American Society for Microbiology

New Vaccine May Protect Against Cervical Cancer

Researchers from Maryland have developed a new DNA vaccine that targets proteins expressed in cervical cancer cells. Their findings appear in the August 2004 issue of the Journal of Virology.

Human papillomavirus (HPV) is found in more than 99 % of cervical cancer cases, which is the second leading cause of cancer death among women throughout the world. Consistently identified in HPV cancer cells, proteins E6 and E7 are the determined cause of malignant transformation.

In the study mice were immunized with a DNA vaccine encoding CRT (a binding protein with many cellular functions) and linked to E6 targeting HPV-associated lesions. Results showed a significant T-cell immune response specific to E6, indicating that a CRT/E6 DNA vaccine could also protect against E6 expressing tumors.

"We have shown that DNA vaccines encoding E6 can generate strong E6-specific CD8+ T-cell immunity and can control the growth of E6-expressing tumor cells," say the researchers. "Therefore, E6 vaccines, and perhaps E6 and E7 vaccines in combination, may represent an important approach to controlling HPV-associated cancers."

(S. Peng, H. Ji, C. Trimble, L. He, Y. Tsai, J. Yeatermeyer, D.A.K. Boyd, C. Hung, T.-C. Wu. 2004. Development of a DNA vaccine targeting human papillomavirus type 16 oncoprotein E6. Journal of Virology, 78. 16: 8468-8476.)


New Antimalarial Compound Identified Through Self-Medicative Behavior of Wild Chimps

French and Ugandan researchers have discovered novel antimalarial compounds by observing the behavior of wild chimps. Their findings appear in the August 2004 issue of the journal Antimicrobial Agents and Chemotherapy.

In the study researchers observed a Kanyawara community of fifty wild chimpanzees for unusual feeding behaviors, especially those of ill chimps. Stool and urine samples were collected for analysis. The occasiona
'"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
17-Aug-2004


Page: 1 2 3

Related biology news :

1. Select research highlights from current AACR journals
2. Open Access journals proven to compete on quality
3. Tips from the journals of the American Society for Microbiology
4. American Society of Plant Biologists offers developing nations free access to science journals
5. BioMed Central to deposit e-journals with the British Library
6. ASM journals tipsheet: May 2001
7. Tipsheet: April journals of the American Society for Microbiology
8. Tips from the journals of the American Society for Microbiology: February 2001
9. Highlights of the October 2004 Journal of the American Dietetic Association
10. The American Phytopathological Society announces 2004 awards
11. Tips from the Journals of the American Society for Microbiology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/17/2017)... 2017 NXT-ID, Inc. (NASDAQ: NXTD ) ... of its 2016 Annual Report on Form 10-K on Thursday April ... ... in the Investor Relations section of the Company,s website at ... at http://www.sec.gov . 2016 Year Highlights: ...
(Date:4/13/2017)... PUNE, India , April 13, 2017 According ... Identity Proofing, Identity Authentication, Identity Analytics, Identity Administration, and Authorization), Service, Authentication ... by MarketsandMarkets™, the IAM Market is expected to grow from USD 14.30 ... Annual Growth Rate (CAGR) of 17.3%. ... ...
(Date:4/11/2017)... 11, 2017 Research and Markets has announced ... report to their offering. ... global eye tracking market to grow at a CAGR of 30.37% ... Tracking Market 2017-2021, has been prepared based on an in-depth market ... landscape and its growth prospects over the coming years. The report ...
Breaking Biology News(10 mins):
(Date:9/17/2017)... ... 17, 2017 , ... GeneOne Life Science, Inc. announces that ... Safety (KMFDS) for an Investigational New Drug application for a Phase I/IIa study ... The study in Korea represents the second clinical trial for GLS-5300. , ...
(Date:9/14/2017)... ... September 14, 2017 , ... Boston Strategic ... experience with Health Economics and Outcomes Research (HEOR) and ‘big data’ to provide ... 2014, US healthcare spending exceeded $3.0 trillion with nearly 1/3 spent on hospitalizations. ...
(Date:9/13/2017)... ... 13, 2017 , ... AMRI, a global contract research, development ... and quality of life for more than 25 years, today announced that John ... the International Standards Organization/Technical Committee 194: Biological and Clinical Evaluation of Medical ...
(Date:9/12/2017)... (PRWEB) , ... September 12, 2017 , ... It wasn’t ... months, it has been hot, hot, hot, as Lajollacooks4u has had a record-breaking number ... , Guests came from far and wide to celebrate company outings, family get-togethers, anniversaries ...
Breaking Biology Technology:
Cached News: