Topical oxygen helps hard-to-heal wounds heal faster ...( Photos were taken before...)

Photos were taken before, during, and at the completion of the therapy. Wounds were considered healed once they were completely covered with epithelial tissue. Follow up ranged from less than one month to eight months. When a wound hadn't begun to heal after 16 weeks, physicians attempted to close the injury with surgery.

Acute traumatic and post-surgical injuries had the best healing rates: such wounds on the trunk, arms and hands had a 75 percent and 100 percent healing rate, respectively. Half of all acute wounds on the legs and feet healed. Chronic wounds that responded well to the oxygen therapy included venous stasis ulcers (92 percent healing rate) and diabetic hand ulcers (91 percent healing rate), while bedsores had a less encouraging 44 percent healing rate.

"The differences in healing rates reinforce a link between other health conditions, such as diabetes and obesity, and wound healing outcomes," said Sen, who is also the associate director of the Davis Heart and Lung Research Institute. Most patients in the study had at least one health condition, such as diabetes, cancer or an active infection.

Overall, the wounds least responsive to topical oxygen therapy were post-surgical wounds on the legs and feet, pressure ulcers and neuropathic foot ulcers.

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Contact: Chandan Sen
Sen.16@osu.edu
614-247-7786
Ohio State University
28-Jan-2003

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