U-M researchers seek answers for African-Americans at risk for prostate cancer

wed the same link in Caucasian men.

"This study adds to an expanding body of evidence in support of the germ-line MSR1 mutations as risk factors for prostate cancer. Although our study was modest in size, the public health burden of prostate cancer in the African-American community warrants further attention to potential genetic risk factors," says David Miller, M.D., a resident in Urology at the U-M Medical School and lead author of the report.

While scientists believe there is a strong hereditary link in prostate cancer, it's been difficult to pin down the exact genes involved in this disease. Many men develop prostate cancer later in life, and some men may die before prostate cancer even develops, making it difficult to trace the disease through generations of families.

Knowing the genetic markers involved in prostate cancer could help determine which men are at highest risk. Currently, physicians say men with a family history of the disease and African-American men are at the highest risk. Genetic risk factors could help narrow that down even further, indicating when more aggressive tests or therapies are necessary.

In addition to this paper, the Flint Men's Health Study has looked at prostate-specific antigen, or PSA, levels and differences in the frequency and severity of prostate cancer symptoms in African-American men. The study began collecting data in 1996 and identified 817 eligible African-American men ages 40-79 to participate. The study subjects were recruited from Flint, Mich., an urban area north of Detroit with a high African-American population. Of the eligible group, 369 participants underwent an interview, clinical exam and serum test. Researchers contacted the participants again in 2000 for further testing; 183 took part in the second wave.

Aside from the large African-American participation, the study is unusual because it recruited people through the community, not through a hospital setting. Part of the di

Contact: Nicole Fawcett
University of Michigan Health System

Page: 1 2 3 4

Related biology news :

1. Belgian researchers explore revolutionary approach to angiogenesis
2. Award winning researchers reveal potential new role for Glivec
3. $7.5 Million grant to Yale researchers for role of viruses in cancer
4. New anti-inflammatory strategy for cancer therapy identified by UCSD researchers
5. Joslin researchers clarify mechanisms for beta-cell formation
6. Virginia Tech researchers to release findings on Smith River Project
7. Molecular motor myosin VI moves hand over hand, researchers say
8. ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
9. Emory researchers map structure of anti-cancer molecule
10. Leukemia stem cells identified by Stanford researchers
11. EURYI Award given for the first time to 25 young European researchers

Post Your Comments:

(Date:6/28/2020)... ... June 25, 2020 , ... In an upcoming episode scheduled for the ... of Care Testing solutions (POCT). Check local listings for more info. , Today, the ... and are shipped to labs throughout the country. Results are then available several days ...
(Date:6/23/2020)... ... June 22, 2020 , ... The field of quantitation of large ... (LBA) have dominated this area. However, the use of mass spectrometry in this field ... necessitates the question “How do you choose which approach to use (LBA or MS)?” ...
(Date:6/19/2020)... ... June 18, 2020 , ... Biosero ... Data Decisions,” for pharmaceutical and biotech executives, laboratory managers, scientists, researchers and ... instruments and laboratory equipment from dozens of manufacturers into their lab. , ...
Breaking Biology News(10 mins):
(Date:7/10/2020)... ... July 09, 2020 , ... ... that Massachusetts Institute of Technology (MIT) has expanded the company’s exclusive license ... to move into the point-of-care diagnostic market, focusing initially on the SARS-CoV-2 ...
(Date:7/1/2020)... ... 2020 , ... MedShift , a leading medical technology ... obstacles created as a result of COVID-19. As a provider at the forefront ... and medical manufacturers by expanding access to device offerings, technology services, and marketing ...
(Date:6/28/2020)... ... June 25, 2020 , ... ... therapy for treating cancer, today announced the company has entered a license agreement ... The agreement provides Lumeda globally exclusive rights to Roswell Park intellectual property surrounding ...
(Date:6/23/2020)... ... June 22, 2020 , ... Dracen Pharmaceuticals Inc., announced ... June 22-24 during the American Association for Cancer Research Virtual meeting. One poster ... potent, consistent single agent activity in KEAP1 mutant tumor models of NSCLC. ...
Breaking Biology Technology:
Cached News: