HOME >> BIOLOGY >> NEWS
U.S.-German research consortium sequences genome of versatile soil microbe

including phenylalkanoates, ferulate, vanillate, and coniferyl- and coumaryl alcohols, aldehydes and acids. TIGR Assistant Investigator Ian Paulsen, who explored the correlation of metabolic pathways with membrane transport capability, said P. putida has "lots of novel pathways and transport capabilities to break down aromatic and other unusual compounds."

The P. putida genome also was compared to that of other species to reveal details about the microbe's evolutionary history. Perhaps the most revealing comparison was with the genome of another member of the Pseudomonas genus P. aeruginosa, which is an opportunistic pathogen and the leading cause of death for cystic fibrosis patients.

TIGR evolutionary biologist Jonathan Eisen said, "Such comparisons among closely related species with different biological properties are invaluable in learning about the biology of each species. In this case it allows us to better identify the features in the P. aeruginosa genome that contribute to making it a pathogen."

An analysis by Tuemmler and Christian Weinel of the MHH identified numerous chemosensory systems, cell attachment factors, and transport systems in P. putida that had been thought to be involved in virulence in P. aeruginosa. For example the KT2440 (P. putida) genome contains a chromosomal region that is present in 85% of P. aeruginosa clinical isolates from sepsis and urinary tract infections. "That suggests that those genes many not be specific for virulence," said Eisen. The researchers did, however, find many genes in P. aeruginosa and not P. putida that had not previously been identified as candidates for being involved in pathogenicity. The identification of such genes may help biomedical researchers pinpoint potential targets for developing drugs or vaccines against this pathogen.


'"/>

Contact: Robert Koenig
rkoenig@tigr.org
301-838-5880
The Institute for Genomic Research
2-Dec-2002


Page: 1 2 3

Related biology news :

1. Leader in cancer treatment and prevention research honored
2. UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
3. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
4. Belgian researchers explore revolutionary approach to angiogenesis
5. Award winning researchers reveal potential new role for Glivec
6. New research shows plants can shuffle and paste gene pieces to generate genetic diversity
7. 16 APS exercise research highlights, from reduced flu mortality to proteomics & obesity
8. Gene chips research in cotton could lead to superior variety
9. Groundbreaking research could ignite new solutions to heat transfer in nano-devices
10. New hydrothermal vents discovered as South Pacific Odyssey research begins
11. University of Alberta researcher looks for clues to mysterious disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/18/2016)... March 18, 2016 --> ... Biometrics, ICT, Manned & Unmanned Vehicles, Physical infrastructure and Perimeter ... companies in the border security market and the continuing migration ... Europe has led visiongain to publish ... success. --> defence & security companies in ...
(Date:3/15/2016)... -- Yissum Research Development Company of the Hebrew ... Hebrew University, announced today the formation of Neteera ... human biological indicators. Neteera Technologies has completed its first ... ... emissions from sweat ducts, enables reliable and speedy biometric ...
(Date:3/11/2016)... 11, 2016 http://www.apimages.com ) - --> ... is available at AP Images ( http://www.apimages.com ) - ... used to produce the new refugee identity cards. DERMALOG will be ... CeBIT in Hanover next week.   --> ... be used to produce the new refugee identity cards. DERMALOG will ...
Breaking Biology News(10 mins):
(Date:4/29/2016)... , ... April 29, 2016 , ... ... devices used in spinal surgical procedures, today announced the completion of a significant ... proposition for current and future customers and partners. Kohlberg & Company, L.L.C. ...
(Date:4/29/2016)... Louisville, KY and San Diego, CA (PRWEB) , ... April 29, ... ... the National Stem Cell Foundation (NSCF) to support the development of a patient-specific stem ... by Dr. Andrés Bratt-Leal in the lab of Dr. Jeanne Loring at The Scripps ...
(Date:4/28/2016)... , April 28, 2016 The ... and Brayton Cryocoolers), Service (Technical Support, Product Repairs & ... - Global Forecast to 2022", published by MarketsandMarkets, the ... Billion by 2022, at a CAGR of 7.29% between ... data Tables and 94 Figures spread through 159 Pages ...
(Date:4/28/2016)... (PRWEB) , ... April 28, 2016 , ... ... Asymmetrex will deliver a talk on its first-in-class technologies for tissue stem ... 2016 Meeting on RNAiMicroRNA Biology to Reprogramming & CRISPR-based Genome Engineering in ...
Breaking Biology Technology:
Cached News: