HOME >> BIOLOGY >> NEWS
UB Fertility Researchers Find They Can Predict Pregnancy By Assessing Two Sperm Abnormalities

SAN DIEGO, Calif. -- Fertility researchers at the University at Buffalo School of Medicine and Biomedical Sciences have found a link between specific clinical pregnancies and very low levels of two sperm abnormalities.

The two abnormalities -- premature chromosomal decondensation and premature acrosome reaction, which are overlooked in a standard semen analysis -- had never been linked to low pregnancy rates, said Lani J. Burkman, Ph.D., UB assistant professor of gynecology and obstetrics, and urology, and head of the Andrology Section of the UB Department of Gynecology-Obstetrics.

By analyzing hundreds of semen samples and comparing them with subsequent pregnancies in the couples studied, Burkman and colleagues determined that samples showing more than 14 percent premature chromosomal decondensation or more than 7 percent premature acrosome reactions had only a slim chance of leading to a pregnancy.

"We were surprised to see that these two factors related to pregnancy so clearly," said Burkman, lead researcher on the study. "This is a new finding, and it's impressive because the test is so simple."

Burkman will present results of the study today (June 2) at the meeting of the American Urology Association.

The acrosome is a enzyme-filled cap covering half the sperm head. Just before fertilization, enzymes from the acrosome, activated at the proper time, soften the egg's covering, or zona, allowing the sperm head with its genetic material to fertilize the egg. If the enzymes are released too soon, a process called premature acrosome reaction, the sperm is rendered useless.

Premature chromosomal decondensation refers to the untimely unraveling of the sperm's tightly packed genetic cargo. If this begins before the sperm has penetrated the egg, the sperm head swells and fertilization becomes impossible.

"In our study, when pregnancy occurred, we knew that the partner's sperm were capable of fertilizing
'"/>

Contact: Lois Baker
baker@newsb.buffalo.edu
716-645-2626
University at Buffalo
29-May-1998


Page: 1 2

Related biology news :

1. Fertility study shows increased estrogen shortens window of implantation in mice
2. Fertility treatments increase incidence of twins at a cost
3. Fertility experts urge clinics to consider natural cycle IVF instead of routine use of ovarian stimulants
4. Discovery Of Mutation May Lead To Help For Male Fertility Problems
5. Research Suggests New Way To Gauge A Womans Fertility
6. Sperm Protein May Hold Clues For Fertility And Contraceptives
7. Poetically Timed With Spring, Budding Yeast Yield Possible Insight Into Male Fertility--And Infertility
8. Discovery By Fertility Specialist Offers Promise Of Reducing Multiple BirthsTied To Fertility Treatment
9. Researchers determine genetic cause of Timothy syndrome
10. Researchers find color sensitive atomic switch in bacteria
11. Researchers identify protein promoting vascular tumor growth

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/3/2016)... May 3, 2016  Neurotechnology, a provider of ... MegaMatcher Automated Biometric Identification System (ABIS) , a ... projects. MegaMatcher ABIS can process multiple complex biometric ... combination of fingerprint, face or iris biometrics. It ... and MegaMatcher Accelerator , which have ...
(Date:4/26/2016)... -- Research and Markets has announced the ...  report to their offering.  , ,     (Logo: ... forecast the global multimodal biometrics market to grow ... 2016-2020.  Multimodal biometrics is being implemented ... healthcare, BFSI, transportation, automotive, and government for controlling ...
(Date:4/14/2016)... , April 14, 2016 ... Malware Detection, today announced the appointment of Eyal ... new role. Goldwerger,s leadership appointment comes at ... heels of the deployment of its platform at several ... biometric technology, which discerns unique cognitive and physiological factors, ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... ... its second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” Partnering with experienced ... this eBook by providing practical tips, tools, and strategies for clinical researchers. , ...
(Date:6/23/2016)... -- Houston Methodist Willowbrook Hospital has signed a ... serve as their official health care provider. As ... provide sponsorship support, athletic training services, and most ... athletes and families. "We are excited ... to bring Houston Methodist quality services and programs ...
(Date:6/23/2016)... ... 23, 2016 , ... Supplyframe, the Industry Network for electronics ... Lab . Located in Pasadena, Calif., the Design Lab’s mission is to bring ... designed, built and brought to market. , The Design Lab is Supplyframe’s physical ...
(Date:6/23/2016)... Andrew D Zelenetz ... Published recently in Oncology ... touchONCOLOGY, Andrew D Zelenetz , discusses the ... is placing an increasing burden on healthcare systems ... With the patents on many biologics expiring, interest ...
Breaking Biology Technology:
Cached News: