HOME >> BIOLOGY >> NEWS
UC Berkeley biologist disputes current dogma that genetic mutation is the cause of cancer

Berkeley -- A University of California, Berkeley, scientist is challenging one of the central tenets of cancer research, that cancer results from a chance series of genetic mutations that drive a cell into wild, uncontrolled growth.

Molecular biologist Peter Duesberg, better known for his claim that the human immunodeficiency virus is not the cause of AIDS, contends that mutation is not the cause of cancer. Rather, he says, cancer results from disruption of the normal number of chromosomes in a cell, primarily duplication of one or more chromosomes.

Called aneuploidy, this type of chromosomal abnormality is found in nearly every solid cancer studied to date, but has always been considered a side effect of cancer, not the cause itself.

In a peer-reviewed article in the March 28 issue of the journal Proceedings of the National Academy of Sciences, Duesberg and his colleagues at UC Berkeley argue instead that aneuploidy is the primary cause of cancer and explains many aspects of cancer that the genetic mutation theory cannot.

For some 25 years, Duesberg has pointed out problems with the genetic mutation theory of cancer. Now that the theory has become almost dogma, he is ratcheting up his criticism and receiving support from numerous other scientists

"Peter won't let the field stand still, which is extremely important," said Avery A. Sandberg, chief editor of the journal Cancer Genetics and Cytogenetics. "Once scientists think of one theory as being the de facto theory, we're in great trouble."

If Duesberg is right, it would overthrow a theory that has dominated thinking for the past 15 years, guiding research and dictating how doctors detect and prevent cancer. One field that would feel the impact is cancer screening.

"Rather than looking for mutations in biopsied cells, we should look for aneuploidy as a sign of early cancer," said Duesberg, a professor of molecular and cell biology.

A group of physicians at UC San Francisco is now
'"/>

Contact: Robert Sanders
rls@pa.urel.berkeley.edu
510-643-6998
University of California - Berkeley
4-Apr-2000


Page: 1 2 3 4 5

Related biology news :

1. Landmark gene agreement announced by Samoan government and UC Berkeley for anti-AIDS drug Prostratin
2. Landmark agreement between Samoa and UC Berkeley could help search for AIDS cure
3. Berkeley Lab soil scientist Margaret Torn receives Presidential Early Career Award
4. MSU group reviews Berkeley venture into brave new science funding world
5. UC Berkeley museum biologists to repeat 85-year-old Yosemite National Park wildlife survey
6. Berkeley scientists create first 3-D map of protein universe
7. UC Berkeley scientists detail neural circuit that lets eye detect directional motion
8. UC Berkeley, Joint Genome Institute target chloroplasts for clues to green plant evolution
9. Your brain is teaching your nose new tricks, say UC Berkeley researchers
10. UC Berkeley researchers are developing a microsized microscope that can peek inside living cells
11. Dietary supplements make old rats youthful, may help rejuvenate aging humans, according to UC Berkeley study

Post Your Comments:
(Date:10/29/2014)... both genetic and environmental, have been blamed for ... Some, such as a family history of schizophrenia, ... Toxoplasma gondii , a parasite transmitted by ... viewed with skepticism. , A new study by ... at the University of Pennsylvania,s School of Veterinary ...
(Date:10/29/2014)... household and industrial products are in the environment – ... of them, scientists have yet to determine whether they ... toward doing that by estimating which substances people are ... in the ACS journal Environmental Science & Technology ... the risks to human health of any given substance ...
(Date:10/29/2014)... held in New York City on September 19, 2014, ... Cancer Society Professor of Genome Sciences and Medicine at ... Doctor of Philosophy of Tel Aviv University, was awarded ... , In addition to her honorary degree from TAU, ... TAU School of Medicine, and for the past 18 ...
Breaking Biology News(10 mins):Penn vet professor investigates parasite-schizophrenia connection 2Penn vet professor investigates parasite-schizophrenia connection 3Geneticist and humanitarian: Prof. Mary-Claire King receives Lasker Award 2
(Date:10/31/2014)... York, NY (PRWEB) October 31, 2014 ... such as healthcare, construction, finance and consumer electronics ... For this reason, industry research firm IBISWorld has ... industry to its growing industry report collection. , ... develop software for biometric technologies such as fingerprint, ...
(Date:10/30/2014)...  Ardelyx, Inc. (NASDAQ: ARDX ), ... and metabolic diseases, today announced that it will ... November 6, 2014. Following the announcement, the Ardelyx ... and webcast at 4:30pm ET to review the ... The live webcast can be accessed ...
(Date:10/30/2014)... CA (PRWEB) October 30, 2014 ... today that they have manually curated public data source ... non profit customers. the data is now available ... curates and unifies public and internal data sources for ... and knowledge out of the data that becomes more ...
(Date:10/30/2014)... Grace Century portfolio project, Provia Laboratories , ... the Board, to the National Stem Cell Ethics Committee ... by the Ministry of Health on behalf of the Government ... More than a year after Bahamian Parliament passed the ... Christie said the government has completed the accompanying regulations and ...
Breaking Biology Technology:Biometrics Scan Software in the US Industry Market Research Report Now Available from IBISWorld 2Biometrics Scan Software in the US Industry Market Research Report Now Available from IBISWorld 3Ardelyx to Report Third Quarter 2014 Financial Results on November 6, 2014 2Rancho BioSciences Manually Curated TCGA Data Sets Available 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 3
Cached News: