The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> BIOLOGY >> NEWS
UC Berkeley group finds first prostate cancer antigen, providing hope for an eventual vaccine against the tumor

A discovery by scientists at the University of California, Berkeley, could lead the way to a vaccine against prostate cancer.

The researchers, led by immunologist James P. Allison, a Howard Hughes Medical Institute investigator and professor of molecular and cell biology at UC Berkeley, found a protein on prostate cancer cells that tips off the immune system to the tumor's presence and brings in an armada of immune cells to destroy it.

If the protein, called an antigen, is truly unique to prostate cancer cells, it could lead to diagnostics for prostate cancer and a potential vaccine therapy against the disease, which is the second leading cause of cancer death in men, after lung cancer. This is the first prostate cancer antigen found.

"The hope is twofold," Allison said. "One, knowing what the specific target of the immune system is, we can do some very direct studies of whether it is a prognosticator of favorable outcome of disease. And two, we can start thinking about using the antigens to develop a specific vaccine."

Allison, postdoctoral fellow Marcella Fass, graduate student Rebecca Waitz and their colleagues in the College of Letters & Science at UC Berkeley will report their findings on Wednesday, April 4, at Experimental Biology 2001, one of the largest and most interdisciplinary annual biomedical scientific meetings in the world. It is being held March 31 through April 4 at the Orange County Convention Center in Orlando, Fla.

Allison also will talk about the findings at an 11 a.m. EDT media briefing on Tuesday, April 3, in the meeting's press room.

Allison, director of the Cancer Research Laboratory, is a member of UC Berkeley's Health Sciences Initiative, a collaboration among researchers throughout the campus to tackle some of today's major health problems.

Allison and his colleagues found the cancer antigen by looking in a strain of mice prone to prostate cancer. They treated the mice with a
'"/>

Contact: Robert Sanders
rls@pa.urel.berkeley.edu
510-643-6998
University of California - Berkeley
3-Apr-2001


Page: 1 2 3 4

Related biology news :

1. Landmark gene agreement announced by Samoan government and UC Berkeley for anti-AIDS drug Prostratin
2. Landmark agreement between Samoa and UC Berkeley could help search for AIDS cure
3. Berkeley Lab soil scientist Margaret Torn receives Presidential Early Career Award
4. MSU group reviews Berkeley venture into brave new science funding world
5. UC Berkeley museum biologists to repeat 85-year-old Yosemite National Park wildlife survey
6. Berkeley scientists create first 3-D map of protein universe
7. UC Berkeley scientists detail neural circuit that lets eye detect directional motion
8. UC Berkeley, Joint Genome Institute target chloroplasts for clues to green plant evolution
9. Your brain is teaching your nose new tricks, say UC Berkeley researchers
10. UC Berkeley researchers are developing a microsized microscope that can peek inside living cells
11. Dietary supplements make old rats youthful, may help rejuvenate aging humans, according to UC Berkeley study

Post Your Comments:
(Date:11/23/2009)...PAIGN, Ill. Two new studies reveal in unprecedent...lecules to assemble new proteins and guide them to...udies used molecular dynamics flexible fitting (MD...h two prominent molecular partners. , The first... Sciences , concerns the intimate signaling betwee...
(Date:11/23/2009)...National Institute of General Medical Sciences (NI...IH), is investing $42.3 million for grants in scie... (GO)." NIH developed the GO grant program to stim...nds provided by the American Recovery and Reinvest...rojects that promise to have a significant impact ...
(Date:11/23/2009)...s release is available in German . , A bit ...nt wouldn,t be a bad thing. It could help to add d...easure. However, it must do so constructively. In ...surement with more than just imagination, physicis...ve formulated a theory of spatial perception calle...
Breaking Biology News(10 mins):Computational microscope peers into the working ribosome 2Computational microscope peers into the working ribosome 3NIGMS invests in scientific Grand Opportunities with Recovery Act funds 2NIGMS invests in scientific Grand Opportunities with Recovery Act funds 3Visual assistance for cosmic blind spots 2Visual assistance for cosmic blind spots 3Visual assistance for cosmic blind spots 4ZyDoc Medical Transcription Provides Customized Transcription Workflow Solution for Consolidated Services Group 28CSG 29 56511 1ZyDoc Medical Transcription Provides Customized Transcription Workflow Solution for Consolidated Services Group 28CSG 29 56511 2ZyDoc Medical Transcription Provides Customized Transcription Workflow Solution for Consolidated Services Group 28CSG 29 56511 3pMDsoft Announces Interfaces with Additional EMR EHR Practice Management Hospital and Billing Systems 56507 1pMDsoft Announces Interfaces with Additional EMR EHR Practice Management Hospital and Billing Systems 56507 2pMDsoft Announces Interfaces with Additional EMR EHR Practice Management Hospital and Billing Systems 56507 3pMDsoft Announces Interfaces with Additional EMR EHR Practice Management Hospital and Billing Systems 56507 4pMDsoft Announces Interfaces with Additional EMR EHR Practice Management Hospital and Billing Systems 56507 5Details of DNC Fall Meeting in Austin 56503 1Details of DNC Fall Meeting in Austin 56503 2
(Date:11/23/2009)...v.,Nov.23/PRNewswire-FirstCall/--PDLBioPharma,Inc....ablishedNovember27,2009astheex-dividenddateforits$...omthesecuritizationtransactioncompletedonNovember2...tockholdersofrecordontherecorddate,December1,2009....endat$1.67pershareofcommonstockforpurposesoftheex-...
(Date:11/23/2009)....23/PRNewswire-FirstCall/--NeogenCorporation(Nasda...waselectedtoNeogen,sBoardofDirectorsatthecompany,s...smorethan40yearsofexperienceinthefood,agriculture,...fessorofagriculturaleconomicsatVirginiaTechUnivers...ateschiefagriculturenegotiatorwiththerankofambassa...
(Date:11/23/2009)...Newswire/--ImmuneDesignC or p.(IDC)announcedtodayt...an.Dr.Carterhasasuccessfultrackrec or dinbiotechno...tiveOfficeratZymoGenetics,inSeattle,WAandChiefScie..., (Photo: http://www.newscom.com/cgi-bin/prnh/2...andChiefExecutiveOfficercommented,"Iamdelightedtow...
(Date:11/23/2009)...f.,Nov.23/PRNewswire/--Frost&Sullivan,theGrowt...emonstratingleadershipandinnovationThursday,Novemb...dsBanquetheldinSanAntonio,Texas. ,, (Logo: http...,, TheHealthcareInnovationAwardsaregiventocompa...eryandmanagementofhealthcare.Suchcompanieshaveshow...
Breaking Biology Technology:PDL BioPharma Announces Ex-Dividend Date of November 27 for Special Dividend 2Richard T. Crowder Joins Neogen's Board of Directors 2Immune Design Corp. Announces Appointment of Dr. Bruce L.A. Carter as Executive Chairman and Director 2Excellence in Healthcare Innovation Recognized by Frost & Sullivan 2Excellence in Healthcare Innovation Recognized by Frost & Sullivan 3
Other News:
...rom dusting to dancing, can increase your exposure...y. Whether you are cutting the rug or just vacuumi...t could be harmful to your health.......The report...appears in the March 15 edition of Environmental S...
...ers at UT Southwestern Medical Center at Dallas ha...and abnormal smooth muscle growth, a...finding tha...ics for disorders like hypertension and asthma............Smooth muscle cells are essential for the for...
...apt to stress may provide a key to designing treat... study by researchers at the Salk Institute for Bi... San Diego (UCSD) School of Medicine.... ...Pub...National Academy of Sciences, the study establishe...
...e reproductive biology appears to have been overtu... General Hospital (MGH). In an article in the Mar...ort that female mice retain the ability to make ne...eved that most female mammals are born with a fini...
Household activities release a cloud of dust, increasing exposure to particulate pollution 2Household activities release a cloud of dust, increasing exposure to particulate pollution 3UT Southwestern researchers identify gene as essential for vascular smooth muscle development 2Stress hormones and heart failure 2MGH study finds female mammals produce egg cells into adulthood 2MGH study finds female mammals produce egg cells into adulthood 3MGH study finds female mammals produce egg cells into adulthood 4
...rium that can survive encounters with specific imm...ef that these plentiful white blood cells, known a...ill permit or prevent bacterial infections. A pape...e in The Journal of Immunology. Frank R. DeLeo, P...
..., 2005 -- A microbial community thriving under biz...old mine to researchers in their quest to understa...ese inner workings might apply on a grander scale...., researchers from the Department of Energy's Oak ...
... of Ocelot Pond, Panama, red-eyed tree frog embryo...death decision. The egg clutch, a gelatinous blob...n spied by a bright green parrot snake. In a twin... ......With that bite, the embryos start to wiggle...
ATLANTA--By deciphering the ingenious mechanism used by a particular enzyme to modify bacterial chromosome chemistry, scientists have come a step closer to designing a new kind of drug that could stop
Scientists reveal how disease bacterium survives inside immune system cell 2Scientists reveal how disease bacterium survives inside immune system cell 3ORNL, UC Berkeley unravel real-world clues to Earth's mysteries 2ORNL, UC Berkeley unravel real-world clues to Earth's mysteries 3A whole lot of shaking goin' on triggers early hatching in red-eyed tree frogs 2A whole lot of shaking goin' on triggers early hatching in red-eyed tree frogs 3Scientists take aim at virulent bacteria by decoding machinery of key control enzyme 2