UC Riverside plant pathologist awarded $1 million grant to study virus assembly

RIVERSIDE, Calif. -- (www.ucr.edu) -- UC Riverside's A. L. N. Rao of the department of plant pathology has been awarded a grant of $994,715 by the National Institutes of Health - National Institute of General Medical Science for four years starting Aug. 2003. Rao was awarded the grant for studying 'the mechanism of virus assembly.'

"A fundamental question in virology is how viruses package their genomes into stable virions or virus particles," explained Rao, who is associate professor of plant pathology and associate plant pathologist. "If a virus has to spread to another host, it can only be accomplished if the virus is intact. Hence assembly of the virus is important."

(A virus is a minute infectious agent made up of nucleic acid -- DNA or RNA -- and protein that is totally inert outside the host cell. A mature virus is termed a virion and consists of a shell of protein units arranged around a central molecule of nucleic acid. A genome is all the DNA or RNA in a virus or an organism, encoding all its genes.)

Rao explained that once a virus enters a host cell, it releases its nucleic acid (i.e., the infectious part of the virus) into the cell. This nucleic acid then multiplies, and makes more virus particles, killing the cell and causing disease. To make more virus particles, the nucleic acid needs to synthesize the proteins it contains. One of these proteins, called the 'replication protein,' is made using the host's contents and is in turn used to make new copies of the original nucleic acid. Similarly, another set of special 'coat proteins' are synthesized from the newly made nucleic acids. These coat proteins interact with the newly synthesized nucleic acids to form a virion or virus particle with an incredible precision. This proces

Contact: Iqbal Pittalwala
University of California - Riverside

Page: 1 2 3

Related biology news :

1. Humans march to a faster genetic drummer than primates, UC Riverside research says
2. UC Riverside researcher takes snapshots of the movement of molecules in a billionth of a second
3. UC Riverside researchers discover new way to identify cell growth
4. UC Riverside professor to spend year with US State Department
5. UC Riverside researchers develop low-carb corn with enhanced protein and oil
6. UC Riverside researchers improve drought tolerance in plants
7. Plant sex protein identified at UC Riverside
8. UC Riverside researchers publish paper on botulism detection system
9. UC Riverside to convene conference on genetically modified organisms, Oct. 14-17, 2003
10. UC Riverside study indicates mosquito coils may cause cancer
11. UC Riverside geneticist awarded $2.4 million grant by the National Science Foundation

Post Your Comments:
(Date:10/7/2015)... 8, 2015 --> ... Cards (FPC) during third quarter 2015 amounted to around 960 ... 860 MSEK that was communicated 20 August 2015. ... delivery capacity and a continued growing demand for the company,s ... to be higher than during the third quarter. The revenue ...
(Date:10/5/2015)... http://soundview.co ) releases ... (NASDAQ: NXTD ), a biometric authentication company focused ... http://soundview.co ) releases the following market and ... a biometric authentication company focused on the growing mobile ... http://soundview.co ) releases the following market and ...
(Date:9/30/2015)... 2015  The U.S. Court of Appeals for the ... in favor of Crossmatch ™, affirming the International ... Suprema and its U.S. partner Mentalix violated Section 337 ... that declares it unlawful to engage in "unfair practices" ... Crossmatch,s patents, the 5,900,993 patent and the 7,203,344 patent. ...
Breaking Biology News(10 mins):
(Date:10/8/2015)... -- Today the Wyss Institute for Biologically Inspired Engineering at ... Opsonix Inc. The announcement follows a worldwide ... Development (OTD) and Opsonix Inc. enabling the company ... --> --> ... year in the U.S. — more than prostate cancer, ...
(Date:10/8/2015)... ... October 08, 2015 , ... Talon Innovations, a provider ... and other technology-driven industries, announces that it is one of three finalists for the ... Company.” On Thursday, September 25 Talon Innovations was recognized as a nominee for ...
(Date:10/8/2015)... ... October 08, 2015 , ... Cystic ... transmembrane conductance regulator (CFTR) gene and results in dysfunction of the lungs and ... in the lungs. This mucus is very difficult to clear, blocks the airways ...
(Date:10/7/2015)... -- Boston Scientific (NYSE: BSX ) ... Scientific Connected Patient Challenge , an open innovation contest ... patient monitoring to enhance patient care.  Until January 5, ... ideas and collaborate on solutions through Medstro,s ... Cambridge, MA where they will present their ...
Breaking Biology Technology:
Cached News: