UC Riverside research featured on the cover of JALA

RIVERSIDE, Calif. -- (www.ucr.edu) -- The cover of the April 2003 issue of JALA, the Journal of the Association for Laboratory Automation, features UC Riverside researchers studying bio-sensing and highlights three Technical Report posters appearing in the issue by the same engineers.

The JALA cover story, "Young Scientists Excel at University of California - Riverside," profiles three student researchers, Shalini Prasad, Xuan Zhang and Mo Yang, who work with Mihri Ozkan, assistant professor of electrical engineering and chemical/environmental engineering, and Cengiz Ozkan, assistant professor of mechanical engineering in the Bourns College of Engineering at UC Riverside.

A biosensor is a device involving a biological sensing element that converts a change in an immediate environment to signals that can then be processed. Biosensors have been used for a number of applications ranging from environmental pollution detection to defense monitoring.

Examples of biosensors are pH meters based on ion sensitive field effect transistors (Beckman Instruments, Inc., Fullerton, CA), surface plasmon resonance sensors for label-free detection of antigen-antibody interactions (Pharmacia Biosensor, Uppsala, Sweden) and the glucose monitoring diabetes sensor (MiniMed, Inc., Northridge, CA). Development of many other types of biochemical sensors for a variety of applications ranging from clinical diagnostics to warfare monitoring are currently underway.

The papers in JALA by UC Riverside engineers report that, for the first time, single neuron positioning on microelectrodes in a highly controlled fashion has been achieved. "Neuron cell culture is accompanied by other types of cells called glials," said Mihri Ozkan, co-author of the paper entitled 'Patterned live neural networks by induced electrical fields for bio-sensing' that appears in the journal.

Ozkan explained that the presence of glials co

Contact: Iqbal Pittalwala
University of California - Riverside

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