HOME >> BIOLOGY >> NEWS
UC Riverside researchers discover new way to identify cell growth

RIVERSIDE, Calif. (www.ucr.edu) - In a discovery that has relevance in a variety of fields, including human health, UC Riverside Assistant Professor of Biochemistry Frank Sauer and colleagues at UC Riverside, in Germany, and in Wisconsin, have found a new way to identify when a living cell begins to grow.

"We have found a new marker, established by the cell, to detect the production of an essential protein that indicates cell growth," said Sauer, about a research paper published last month in the prestigious journal, Science.

The paper, entitled, "TAF1 activates transcription by phosphorylation of serine 33 in histone H2B" is the result of four years of work. Co-authors include researchers from the University of Wisconsin-Madison and Heidelberg University.

Medical researchers could use the newly discovered marker as a diagnostic tool to monitor the emergence of cancer. The unwanted 'awakening' of cells from the dormant phase can result in uncontrolled cell growth that is loosely referred to as cancer. "We have developed a tool (antibody) that detects the novel marker and identifies growing cells," Sauer said.

The research paper described the identification of the enzyme that controls cell growth by generating the novel "cell growth" marker. "You can activate the enzyme, or you can deactivate it," Sauer said. "This may be used to create substances that can take a cell from the dormant stage to the active stage, or the other way around. This may help create substances that can stop cancerous cell growth."

All higher organisms derive from a single cell, the fertilized egg that divides to generate different cell types, tissues and organs. Once the task has been completed, cells stop dividing and enter a dormant phase of the cell cycle. So any advance in recognizing the complex interplay of proteins that control and regulate the cell cycle has relevance for the diagnosis and treatment of cancer
'"/>

Contact: Kris Lovekin
kris.lovekin@ucr.edu
909-787-2495
University of California - Riverside
3-Jun-2004


Page: 1 2

Related biology news :

1. Humans march to a faster genetic drummer than primates, UC Riverside research says
2. UC Riverside researcher takes snapshots of the movement of molecules in a billionth of a second
3. UC Riverside professor to spend year with US State Department
4. UC Riverside researchers develop low-carb corn with enhanced protein and oil
5. UC Riverside researchers improve drought tolerance in plants
6. Plant sex protein identified at UC Riverside
7. UC Riverside researchers publish paper on botulism detection system
8. UC Riverside to convene conference on genetically modified organisms, Oct. 14-17, 2003
9. UC Riverside plant pathologist awarded $1 million grant to study virus assembly
10. UC Riverside study indicates mosquito coils may cause cancer
11. UC Riverside geneticist awarded $2.4 million grant by the National Science Foundation

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/6/2019)... ... 05, 2019 , ... Pelican BioThermal , the global ... service center in Mexico City, Mexico. Mexico is the second largest pharmaceutical market ... $1.75 billion in pharmaceutical exports since 2015. The Mexico City network station will ...
(Date:6/4/2019)... ... June 04, 2019 , ... ... salient features of seizure risk signals, usually based on variations of amplitude, frequency ... the only acceptable diagnostic methodology due to the complexity and variability of the ...
(Date:5/31/2019)... ... May 30, 2019 , ... Researchers ... Mayo Clinic, have documented significant differences in the prevalence of hereditary genetic mutations, ... compared to non-Hispanic White women. Results will be presented at the 2019 American ...
Breaking Biology News(10 mins):
(Date:5/15/2019)... ... May 16, 2019 , ... Emulsifiers are the magic bullet ... products rely on these ingredients to create stable quality food that can withstand ... shift triggers food formulators to seek out alternatives for starches, gums and chemical ...
(Date:5/7/2019)... ... May 06, 2019 , ... ... for the growing number of repositories being asked to store cellular products ... the team of contributors who are world leaders, who have shared their expertise ...
(Date:5/2/2019)... S.D. (PRWEB) , ... April 30, 2019 , ... The ... from industrial scale macro breweries to local craft breweries, and even home brewing clubs ... very complex chemical and biological processes, that when mastered can produce a superb product. ...
(Date:4/25/2019)... ... 2019 , ... Frank is an albino, deaf Great Dane. His owners rescued him when he ... health issues. Despite his hearing impairment, he was always an active and playful pup. Frank ... day, every day. As the two grew, playtime became rougher and Frank ended up injuring ...
Breaking Biology Technology:
Cached News: