HOME >> BIOLOGY >> NEWS
UC Riverside researchers discover new way to identify cell growth

RIVERSIDE, Calif. (www.ucr.edu) - In a discovery that has relevance in a variety of fields, including human health, UC Riverside Assistant Professor of Biochemistry Frank Sauer and colleagues at UC Riverside, in Germany, and in Wisconsin, have found a new way to identify when a living cell begins to grow.

"We have found a new marker, established by the cell, to detect the production of an essential protein that indicates cell growth," said Sauer, about a research paper published last month in the prestigious journal, Science.

The paper, entitled, "TAF1 activates transcription by phosphorylation of serine 33 in histone H2B" is the result of four years of work. Co-authors include researchers from the University of Wisconsin-Madison and Heidelberg University.

Medical researchers could use the newly discovered marker as a diagnostic tool to monitor the emergence of cancer. The unwanted 'awakening' of cells from the dormant phase can result in uncontrolled cell growth that is loosely referred to as cancer. "We have developed a tool (antibody) that detects the novel marker and identifies growing cells," Sauer said.

The research paper described the identification of the enzyme that controls cell growth by generating the novel "cell growth" marker. "You can activate the enzyme, or you can deactivate it," Sauer said. "This may be used to create substances that can take a cell from the dormant stage to the active stage, or the other way around. This may help create substances that can stop cancerous cell growth."

All higher organisms derive from a single cell, the fertilized egg that divides to generate different cell types, tissues and organs. Once the task has been completed, cells stop dividing and enter a dormant phase of the cell cycle. So any advance in recognizing the complex interplay of proteins that control and regulate the cell cycle has relevance for the diagnosis and treatment of cancer
'"/>

Contact: Kris Lovekin
kris.lovekin@ucr.edu
909-787-2495
University of California - Riverside
3-Jun-2004


Page: 1 2

Related biology news :

1. Humans march to a faster genetic drummer than primates, UC Riverside research says
2. UC Riverside researcher takes snapshots of the movement of molecules in a billionth of a second
3. UC Riverside professor to spend year with US State Department
4. UC Riverside researchers develop low-carb corn with enhanced protein and oil
5. UC Riverside researchers improve drought tolerance in plants
6. Plant sex protein identified at UC Riverside
7. UC Riverside researchers publish paper on botulism detection system
8. UC Riverside to convene conference on genetically modified organisms, Oct. 14-17, 2003
9. UC Riverside plant pathologist awarded $1 million grant to study virus assembly
10. UC Riverside study indicates mosquito coils may cause cancer
11. UC Riverside geneticist awarded $2.4 million grant by the National Science Foundation

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/13/2018)... ... November 13, 2018 , ... Pharmafusion LLC ... a featured presenter at the upcoming CBI Gross-to-Net (GTN) Summit in Philadelphia on ... Friday, November 16, where conference attendees will have the opportunity to “test drive” ...
(Date:11/13/2018)... ... November 12, 2018 , ... ... virtual events and webinars, will be hosting its 9th Annual Clinical Diagnostics ... technologies and treatments available, and updates in regulatory processes to ensure patient safety ...
(Date:11/9/2018)... ... November 08, 2018 , ... Boekel ... Heating blocks, also known as dry bath incubators are used in laboratories worldwide ... , For the new heating blocks, Boekel Scientific used the same interface ...
Breaking Biology News(10 mins):
(Date:11/5/2018)... NASHVILLE, Tenn. (PRWEB) , ... November 05, 2018 ... ... Accredited radiology and telemedicine company backed by Siemens Healthineers and several healthcare VC ... blockchain based radiology solution and making a history by purchasing tokens and obtaining ...
(Date:11/5/2018)... ... November 05, 2018 , ... 2Blades has ... Activator Like (TAL) effector code technology for applications in advancing research in epigenetic ... in plants. Since its discovery in 2009, the efficacy of TAL effector-based DNA targeting ...
(Date:11/3/2018)... ... , ... Triangle Insights Group, a premier life sciences consulting firm, announced today ... in the United States, appearing on this year’s Inc. 5000 list. Since its ... growth over the previous three years. , Separately, Triangle Insights was also ranked ...
(Date:10/31/2018)... ... October 30, 2018 , ... ... trial at the Campbell Clinic in Memphis, Tennessee. This study enrolled 125 ... standard of care for managing pain after total knee replacement surgery (TKA). , ...
Breaking Biology Technology:
Cached News: