HOME >> BIOLOGY >> NEWS
UC Riverside researchers publish paper on botulism detection system

Researchers at the University of California, Riverside have developed a device that speeds the detection of a virulent strain of botulism neurotoxin from hours or days to minutes, making treatment or vaccination more effective.

Botulinum neurotoxin B, one of five strains that are known to be toxic to humans, is targeted in the paper that appeared in the Nov. 11 issue of the Proceedings of the National Academy of Sciences. The paper's authors included UC Riverside Professor of Cell Biology and Neuroscience Vladimir Parpura and Umar Mohideen, a professor of physics, both part of the Center for Nanoscale Science and Engineering at UC Riverside; graduate student Wei Liu; staff researcher Vedrana Montana; and Edwin Chapman, a professor of physiology at the University of Wisconsin, Madison.

Given its rapid detection and small size, the device, known as a micromechanosensor, will find applications in medicine, in the war against bioterrorism or in the food industry, Parpura said.

"Of course a good deal of testing needs to be done first," Parpura said. "What we've done is shown proof that the principle works."

The principle, he added, works much like a fishing pole and line. A protein-coated bead at the end of a microscopic cantilever comes in contact with the neurotoxin, which cuts through the protein strands connecting the two, much like a fish would cut through a fishing line. The bead's separation causes the cantilever to vibrate, announcing the neurotoxin's presence. While effective, the process is not yet ready for practical application.

"Right now the issue is that it's linked to an atomic-force microscope, an expensive piece of equipment, which means it cannot be used on a widespread basis," Parpura said.

However, he holds out hope that the process could soon be put into wider practice to detect one of the most potent toxins known to man. The Centers for Disease Control and Prevention in Atlanta list botulism as on
'"/>

Contact: Ricardo Duran
ricardo.duran@ucr.edu
909-787-5893
University of California - Riverside
4-Dec-2003


Page: 1 2

Related biology news :

1. Humans march to a faster genetic drummer than primates, UC Riverside research says
2. UC Riverside researcher takes snapshots of the movement of molecules in a billionth of a second
3. UC Riverside researchers discover new way to identify cell growth
4. UC Riverside professor to spend year with US State Department
5. UC Riverside researchers develop low-carb corn with enhanced protein and oil
6. UC Riverside researchers improve drought tolerance in plants
7. Plant sex protein identified at UC Riverside
8. UC Riverside to convene conference on genetically modified organisms, Oct. 14-17, 2003
9. UC Riverside plant pathologist awarded $1 million grant to study virus assembly
10. UC Riverside study indicates mosquito coils may cause cancer
11. UC Riverside geneticist awarded $2.4 million grant by the National Science Foundation

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/23/2020)... , ... August 21, 2020 , ... ... Corporation has been published and is now available on the company’s global ... diffraction—serves the X-ray analysis community, presenting current news and crystallographic research. , ...
(Date:8/12/2020)... ... 2020 , ... Both Roche, based in Basel, Switzerland, and ... with Housey Pharma’s HMI subsidiary to gain access to its core-enabling technology for ... Development spending in excess of US $10 billion. , Scientists at Housey Pharma ...
(Date:8/3/2020)... , ... August 03, 2020 , ... ... announced a new partnership with medical equipment manufacturer, Spectrum Solutions, to provide COVID-19 ... to strengthen their laboratory supply chain for more than 10 years. Early in ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... Texas (PRWEB) , ... July 29, 2020 , ... ... solutions today announced the launch of its new tagline, “BUILDING FOR LIFE.” The ... biopharmaceutical industry and around the globe, requiring fast track capacity to provide patients ...
(Date:7/31/2020)... SOMERSET, N.J (PRWEB) , ... July 29, 2020 ... ... editing company, and Catalent, the leading global provider of advanced delivery technologies, development, ... products, today announced that they have entered into a strategic partnership whereby Catalent ...
(Date:7/31/2020)... ... July 30, 2020 , ... Alucio™, ... announced the release of its signature product called Beacon - a content ... other field medical professionals. , Beacon helps MSLs streamline communication and ...
(Date:7/18/2020)... ... ... “We are thrilled to deliver this new technology to the industry” said ... on the market and we were pleased that the IFT jury recognized that.” reFRESH™ ... creating a natural way to extend the shelf life and improve the safety of ...
Breaking Biology Technology:
Cached News: