HOME >> BIOLOGY >> NEWS
UC Riverside scientists discover wound-healing substance

Many people suffer from the inability to heal properly and open wounds are subject to systemic infections which may lead to death. Now, new research with chickens at the University of California, Riverside has identified a protein pivotal in healing the animals' injuries, findings that have important implications for human healing.

Reporting in the January 2002 issue of the Journal of Cell Biology, Manuela Martins-Green, associate professor of biology, and three of her students note that the chicken chemokine "cCAF" is critical to healing chicken wounds, and appears similar in function to human chemokine interleuken-8 or IL-8.

The discovery may help researchers understand how wound-healing can be accelerated in humans.

Focusing the experimentation on chickens because chickens heal much the way humans do, Martins-Green's laboratory has shown that cCAF can by itself orchestrate much of the wound-healing process, including causing blood vessels to grow toward the wound to replace the blood system damaged by wounding and thereby provide nutrients for the recovering tissue.

Chemokines - small proteins that play important roles in wound healing and in response to cancerous tumors - first became known for their property of attracting white blood cells to sites of inflammation. (Inflammation is an important process in guarding against infection during wound healing and in fighting tumors.) "Our more recent work, still in progress, has shown that interleukin-8 and cCAF can behave in a similar way," Martins-Green says.

In December, 2001, Martins-Green and her students reported at the meeting of the American Society for Cell Biology in Washington, D.C. that IL-8 is also able to stimulate contraction and closure of wounds in chickens. "Both the human and chicken chemokines stimulate a common cell type -- fibroblasts -- to become a slightly different type of cell that has the ability to contract, much like a small muscle," Martins-Gr
'"/>

Contact: Iqbal Pittalwala
iqbal@citrus.ucr.edu
909-787-2645
University of California - Riverside
23-Jan-2002


Page: 1 2

Related biology news :

1. Humans march to a faster genetic drummer than primates, UC Riverside research says
2. UC Riverside researcher takes snapshots of the movement of molecules in a billionth of a second
3. UC Riverside researchers discover new way to identify cell growth
4. UC Riverside professor to spend year with US State Department
5. UC Riverside researchers develop low-carb corn with enhanced protein and oil
6. UC Riverside researchers improve drought tolerance in plants
7. Plant sex protein identified at UC Riverside
8. UC Riverside researchers publish paper on botulism detection system
9. UC Riverside to convene conference on genetically modified organisms, Oct. 14-17, 2003
10. UC Riverside plant pathologist awarded $1 million grant to study virus assembly
11. UC Riverside study indicates mosquito coils may cause cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/17/2019)... ... September 17, 2019 , ... Dual-board certified periodontist ... the Australia Society of Implant Dentistry (ASID) Accreditation Courses. His lecture, “Understanding the ... Surgical Aspects of Modern Implant Dentistry course. Dr. Kim’s expertise comes from years ...
(Date:9/8/2019)... Md. (PRWEB) , ... September ... ... biotechnology market disrupter and leading supplier of innovative human mesenchymal stem/stromal cell ... first human umbilical cord (hUC) MSC paired cell and media system designed ...
(Date:8/29/2019)... CARLSBAD, Calif. (PRWEB) , ... ... ... daacro (Diagnostic Assessment and Clinical Research Organization), have recently passed ... combines CRO standards, hormone diagnostics and psychoneuroendocrine stress expertise, with a primary ...
Breaking Biology News(10 mins):
(Date:9/11/2019)... ... September 09, 2019 , ... Tunnell ... government agencies, announced that its president and CEO Maryann Gallivan has been accepted ... , The Forbes Council accepted Gallivan based on the role she and ...
(Date:9/11/2019)... N.J. (PRWEB) , ... September 10, 2019 , ... ... development, and manufacturing solutions for drugs, biologics, gene therapies, and consumer health products, ... Forum, to be held at the Bausparkasse Schwäbisch Hall AG, Schwabisch Hall, Germany, ...
(Date:9/8/2019)... ... 2019 , ... Spartan Bioscience, the leader in on-demand DNA ... has been named Chief Financial Officer. , Spartan has also named former ... Additionally, Spartan has hired Steve Edgett as Executive Vice President to lead international ...
(Date:8/29/2019)... (PRWEB) , ... August 29, 2019 , ... ... chronic disease affecting grapevines, a feat they hope will ultimately help protect the ... Researchers including several Rochester Institute of Technology faculty and alumni sequenced the microbiome ...
Breaking Biology Technology:
Cached News: