of the tool is a simple 3 x 1 inch glass slide -- the kind found in a high school science laboratory. Scientists bond DNA or RNA sequences to the slide, wash fluorescently tagged DNA or RNA sequences of interest over it and see where the two sets of nucleic acid match up, as indicated by the fluorescent light. The outcome reveals which, if any of the genes in the sample of interest are active.
Ever interested in providing free access to scientific information, DeRisi has made a point of posting instructions on his website for making microarrays, and has given several workshops on their construction at Cold Spring Harbor and UC Santa Cruz.
"Joe has made a monumental effort to improve technology, creatively applying it to exciting disease-oriented problems, and making it accessible and freely available. Already, dozens of laboratories and hundreds of students have directly benefited from the resources he has developed and made available to the scientific community," says Walter.
"He is an outstanding researcher, a talented and dedicated teacher, an active participant in university and public service, and a wonderful human being. Joe's impact to date has been well beyond our wildest expectation. Among the many lucrative projects that could be tackled with microarray technology, Joe has focused a significant fraction of his research on malaria, a disease primarily afflicting the Third World. This focus is motivated by his genuine desire to have a positive impact on the human condition."
Page: 1 2 3 4 5 Related biology news :1
Contact: Jennifer O'Brien
University of California - San Francisco
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