research funded by the grant will focus on technologies to map the "glycome" of stem cell lines established by Bresagen, a private research company with offices and laboratories in Athens. "Glycome" describes all the complex carbohydrates attached to proteins and lipids that are made by a cell, as well as the enzymes responsible for their metabolism. It also describes the carbohydrate binding proteins that function by recognizing these complex carbohydrates.

"This proposal was one of only seven funded nationally in this first grant competition, so naturally, we are pleased," said Pierce.

This technology will allow the glycomic analysis of small numbers of cells and the means to isolate or kill these particular cells. The expected outcome will be directly applicable to the isolation of certain types of nerve cells for treatment of such diseases as Parkinson's, as well as development of new ways to diagnose and treat cancer.

Others in the research project include Kelley Moremen, Ron Orlando, Parastoo Asadi and Will York of the CCRC; Armit Sheth, John Miller and Krzysztof Kochut of UGA's computer science department and its Large Scale Distributed Information Systems Laboratory; Ian Lyons of Bresagen, Inc. (and an adjunct professor of biochemistry and molecular biology at UGA); and Alfred Merrill of Georgia Tech.

The Georgia Cancer Coalition (GCC) is a statewide public-private network of people and organizations - doctors, hospitals, government agencies, public health services, survivor and community health groups, universities, industries, nonprofits and interested individuals - working together to save lives and reduce human suffering from cancer.

Russ Toal, president of the Georgia Cancer Coalition, noted that "this grant award underscores Georgia's and UGA's determination to fight cancer with the best weapons in our arsenal: university leadership, quality faculty, world-class research, multi-institutional collaborations, publ
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Contact: Kim Carlyle
kcarlyle@uga.edu
706-583-0913
University of Georgia
5-Sep-2003

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