UMass Researchers Announce Birth Of Genetically Modified Cloned Calves

d last year between ACT and Genzyme Transgenics Corp., the first product to be produced will be human serum albumin, a protein currently derived from pooled human plasma that is used therapeutically to maintain volume in blood vessels. Approximately 440 metric tons of plasma-derived albumin are used annually worldwide. Combining cloning and transgenics to produce recombinant human albumin may provide a safe and more cost-effective substitute for the plasma-derived product. An individual cloned transgenic dairy cow is expected to produce approximately 80 kilograms of recombinant human albumin annually.

Also, scientists newfound ability to endow cattle offspring with desirable genetic characteristics is being pursued as a method of producing modified cells for transplantation into human patients, according to Stice. Genetic modification may be used to reduce the chance of rejection of foreign organs, tissues, and bone marrow transplants, and produce therapeutic proteins and improve survival in cell transplants. These cells are currently being tested in animals for treating such disorders as Parkinsons disease. Many other disorders, such as Alzheimers disease, Huntingtons disease, and diabetes, could be treated in the future using this type of cell-based therapy, Stice said.

Robl and Stice make the desired changes in the genetic code, or DNA, of scores of somatic cells that are candidates to become the clones genetic donor. This process is more labor-intensive than it sounds: only one in a million cells have the gene alteration that the scientists hope to produce. These select cells are then grown in a petri dish and fused to cow eggs in which the original genetic material has been removed. The resulting embryos are implanted in surrogate mothers. The resulting offspring, all of one sex, will be identical to one another and carry the same genetic information.

The first cloned animals were born in th

Contact: Elizabeth Luciano
(413) 545-0444
University of Massachusetts at Amherst

Page: 1 2 3

Related biology news :

1. UMass scientist identifies gene that governs obesity, physical activity, sex behaviors in mice
2. UMass team to study bioremediation of acid, heavy metals from collapsed mind
3. Microorganisms are cleaning up Boston Harbor, UMass study finds
4. UMass researcher helping the EPA to determine health effects of spent rocket fuel
5. UMass anthropologist investigates dental development and body size in primates
6. UMass microbiology team probes bacteriums surprising survival tactics
7. UMass study uses microbes to turn mud into electricity
8. UMass researchers find environment on Earth that mimics Mars geochemically and supports ancient life form
9. A sticky situation for ants and bees: UMass biologist looks at how these insects adhere to various surfaces
10. UMass sponsoring world environmental conference
11. Galapagos finches sing different mating songs due to evolutionary diversification of beaks, says UMass biologist

Post Your Comments:

(Date:8/27/2019)... (PRWEB) , ... August 27, 2019 , ... ... company, announced today new opportunities to improve genetic testing guidelines. In the largest ... improve the guidelines to identify more at-risk patients. , Clinicians use guidelines ...
(Date:8/23/2019)... ... August 22, 2019 , ... R121 ... their acquisition in June of 2018. Along with the name change, this rebranding ... “Our goal was to create a cohesive brand that blended our core foundation ...
(Date:8/19/2019)... ... August 19, 2019 , ... Since the microscope was first ... dimensional slices which are placed on microscope slides, stained and visualized by a ... features such as vasculature and thus researchers in the last few years have ...
Breaking Biology News(10 mins):
(Date:9/11/2019)... ... 10, 2019 , ... An upcoming episode of Advancements with ... genome sequencing analysis. Check your local listings for more information. , Advancements will ... Consulting and will explore its revolutionary pathogenic DNA analysis technology, which predicts in ...
(Date:9/9/2019)... ... September 09, 2019 , ... Visikol CEO Dr. Michael Johnson recently gave a ... best to characterize 3D cell culture models. The inherent problem of characterizing 3D cell ... opaque to image through and therefore traditional wide-field or even confocal microscopy only tells ...
(Date:9/8/2019)... ... 05, 2019 , ... Spartan Bioscience, the leader in on-demand ... Shopify, has been named Chief Financial Officer. , Spartan has also named ... advisors. Additionally, Spartan has hired Steve Edgett as Executive Vice President to lead ...
(Date:9/2/2019)... and LIÉGE, Belgium (PRWEB) , ... September 02, ... ... solutions for epigenetics research and in vitro diagnostics, has launched the industry’s first ... uncover the underlying biological meaning of epigenetic data and other data types. , ...
Breaking Biology Technology:
Cached News: