HOME >> BIOLOGY >> NEWS
UNC Researchers Develop New Way To Measure Acid Level Of Body Fluids

CHAPEL HILL, N.C. - Scientists at the University of North Carolina at Chapel Hill have invented a solid-state metal sensor -- roughly the thickness of three human hairs -- that can measure the acidity (pH) of chemical solutions, including body fluids.

A report describing the invention, including successful laboratory tests in animals, is published in the December issue of Analytical Chemistry.

"This particular electrode can be applied to any solution ? from a chemical process in the laboratory to the measurement of tissue pH in physiologic studies," says co-inventor Dr. Wayne E. Cascio, associate professor of medicine at the UNC-CH School of Medicine.

But according to new findings by Cascio and his UNC-CH colleagues, the pH electrode may even prove useful for monitoring the hearts of hospitalized patients, especially those in intensive coronary care. Attached to the tip of a catheter and then threaded via vein to the heart, the pH electrode may offer advance warning when cardiac muscle is becoming more acidic, a condition that occurs during ischemia. Ischemia takes place when the supply of oxygen is cut to portions of the heart and can arise from fat-clogged coronary arteries. This condition could lead to a heart attack.

"If the pH is falling, indicating more acidity, then you know that the tissue is ischemic," Cascio, a cardiologist, explains. "The process of ischemia generates acid, and the degree of acidification offers an index of the severity of ischemia. But a falling pH also seems linked to other electrical and metabolic changes that occur and can predispose to heart rhythm disturbances such as ventricular fibrillation and sudden death," he adds.

In terms of pH in the human body, metabolic actions occur properly when fluids are close to chemical neutrality ? neither too acid nor too alkaline. On a scale of zero to 14, a pH of below 7 signals acidity. In cardiac tissue, ischemia results in the loss of protons from cells, which leads to
'"/>

Contact: Lynn Wooten
lwooten.est1@mail.unch.unc.edu
919-966-6046
University of North Carolina School of Medicine
11-Nov-1998


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/16/2018)... , ... October 16, 2018 ... ... leader in delivering cloud-based enterprise-class unified communications and collaboration solutions, announced today ... stability by directly connecting CallTower data centers to a customers’ network. CallTower’s ...
(Date:10/11/2018)... , ... October 09, 2018 , ... Exalto Bearings ... marine industries, announces the appointment of Mike Cosgrove as Business Manager. , Cosgrove has ... responsible for the day to day running of the Derby UK facility. , “We ...
(Date:10/5/2018)... ... October 05, 2018 , ... The Amino ... announcing a 10% price increase across all markets in January 2019. , ... building blocks of protein — for the parenteral nutrition, biopharmaceutical, infant/medical food, supplement ...
Breaking Biology News(10 mins):
(Date:10/5/2018)... ... 04, 2018 , ... Karius , a life sciences ... at IDWeek™ 2018 the positive results of a study demonstrating that the Karius® ... causative pathogens in patients with infective endocarditis even when blood cultures were negative ...
(Date:10/2/2018)... ... October 02, 2018 , ... ... Bio-Energy Solutions™, LLC’s (Locus Bio-Energy) AssurEOR product line was chosen for its advancements ... Gulf Energy Information, honor leading innovations in upstream oil applications that are positively ...
(Date:9/28/2018)... ... September 28, 2018 , ... LabRoots , ... and scientists from around the world, is excited to announce Daniel Andrade, a ... as the winner of the LabRoots Summer 2018 Textbook Scholarship, awarding him $1,000 ...
(Date:9/27/2018)... ... September 27, 2018 , ... ... Everwell Health Solutions and SureAdhere Mobile Technology, Inc. announced they will formally merge ... in the battle against tuberculosis (TB) and other diseases. These two social enterprise ...
Breaking Biology Technology:
Cached News: