HOME >> BIOLOGY >> NEWS
UPMC Reports On New Liver Assist Device

PITTSBURGH, April 23 -- Preliminary results of a new bio-artificial liver assist device were presented by University of Pittsburgh Medical Center (UPMC) researchers today at the 44th annual American Society for Artificial Internal Organs (ASAIO) conference in New York City. The device, designed by Excorp Medical Inc., significantly improved liver failure in animal studies, and researchers anticipate their results will help secure approval to begin studies in humans soon.

The researchers are awaiting U.S. Food and Drug Administration (FDA) approval to allow further testing in humans as a phase I clinical trial which will evaluate whether the device is safe.

The Excorp bio-artificial liver assist device is intended to provide temporary support to patients with acute liver failure until their liver recovers spontaneously or until transplantation is possible. When human trials begin, researchers will place patients with acute liver failure on the device, which is connected to a vein and remains outside their bodies. Researchers believe it should help remove toxins from the patient's own liver cells, as the patient's blood circulates in a chamber with pig liver cells inside polymer membranes. The membranes allow toxins to pass through, but prevents proteins, and other cell byproducts from the pig cells to get into the patient's blood.

"Initially, the agreement between UPMC and Excorp allowed researchers to gather engineering and pre-clinical information about the device," said Jack Patzer, Ph.D., assistant professor of surgery and chemical engineering at the University of Pittsburgh, who presented the findings at the ASAIO meeting.

"But with the bio-artificial liver assist device demonstrating such a significant impact on the course of liver failure in our animal trials, we hope within the month to secure FDA approval to begin phase I human t
'"/>

Contact: Lisa Rossi
RossiL@a1.isd.upmc.edu
(412) 624-2607
University of Pittsburgh Medical Center
23-Apr-1998


Page: 1 2 3

Related biology news :

1. Reports of "weird life" almost stranger than fiction
2. Reports from special environmental health issue explore links to autoimmune diseases - diabetes, lupus, multiple scleroris and arthritis
3. Osiris Therapeutics Reports Key Findings in SCIENCE Verifying Existence of Adult Stem Cells
4. Abgenix Reports Encouraging Preclinical Results With ABX-EGF In Cancer Research
5. New England Journal Of Medicine Reports Calcium Supplements Help Prevent Polyp Recurrence; DMS Led Study
6. Duke Scientist Reports Advances In Gene Therapy For Heart Failure
7. North America Absorbing Carbon Dioxide At Surprisingly High Rate, Team Reports
8. University Of Pittsburgh Reports Novel Ways To Improve Transplant Acceptance At Transplantation Society Meeting
9. Cell Pathways Reports Extension Study Results Showing Ability Of FGN-1 To Prevent Formation Of Precancerous Colon Polyps
10. Reports Mesh To Clarify Proteins Importance For Cancer
11. Infant Dependency Drives Menopause, NSF-Supported Researcher Reports

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/16/2018)... POWAY, Calif. (PRWEB) , ... October 16, 2018 , ... ... taken to look for a possible tumor and instead, Sam’s veterinarian found that he ... not experiencing any obvious discomfort, so his owner placed him on supplements for the ...
(Date:10/16/2018)... ... October 15, 2018 , ... Modality Solutions, ... regulated industries, is a silver sponsor and exhibitor at the Executive Platforms’ Biomanufacturing ... The Biomanufacturing World Summit brings together the “who’s who” of pharmaceutical executives, cutting-edge ...
(Date:10/16/2018)... Utah and BOSTON (PRWEB) , ... ... ... CallTower , a global leader in delivering cloud-based enterprise-class unified communications and ... Boost delivers enhanced network stability by directly connecting CallTower data centers to ...
Breaking Biology News(10 mins):
(Date:10/3/2018)... (PRWEB) , ... October 03, 2018 , ... Milwaukee Area ... open house Wednesday, Oct. 17, from 3-7 p.m. in Room T129 in the T ... to its new CNC Swiss Lab. A ribbon cutting and formal program will be ...
(Date:10/2/2018)... ... 2018 , ... The Alliance for Clinical Research Excellence and ... standards and testing of procedures for voluntary accreditation of clinical research sites. The ... Quality Management Systems and Chief Quality Officer, is underway in association with ...
(Date:9/27/2018)... ... September 26, 2018 , ... ... Melina Cimler, a senior quality, regulatory, and in vitro diagnostic device expert with ... diagnostic industry has joined the firm as an Expert Consultant. Her experience includes ...
(Date:9/27/2018)... ... September 27, 2018 , ... ... Everwell Health Solutions and SureAdhere Mobile Technology, Inc. announced they will formally merge ... in the battle against tuberculosis (TB) and other diseases. These two social enterprise ...
Breaking Biology Technology:
Cached News: