HOME >> BIOLOGY >> NEWS
USC study links historical increases in life span to lower childhood exposure to infection

Starting in the mid-1850s, humans began living longer due, researchers believe, to improvements in living conditions, nutrition, income levels and medicine.

But two USC gerontologists have found an invisible cause that could have important implications for modern-day health care.

In a paper published in the Sept. 17 issue of the journal Science, Caleb Finch and Eileen Crimmins firmly link this gradual yet steady increase in human life span to lower childhood rates of exposure to infectious diseases such as tuberculosis and malaria.

The key to their theory lies in one word: inflammation.

Infectious diseases cause chronic inflammation in the blood that, decades later, leads to heart attacks, strokes and cancers the classic killers of old age.

"We've put pieces together that are in front of everybody's nose and made a coherent hypothesis," said Caleb Finch, the study's lead author and holder of the ARCO-William F. Kieschnick Chair in the Neurobiology of Aging.

"Our main point is that in historical times when there was a lot of childhood mortality, even kids that didn't die got chronic infections. Those chronic infections from childhood onward accelerated vascular and other diseases," he said.

Finch and Crimmins, holder of the Edna M. Jones Chair in Gerontology, studied data on the health and mortality rates of people born in Sweden from 1751 to 1940. Grouping them by birth year into what are called birth cohorts the researchers found that as public health efforts led to less exposure to infectious diseases during childhood, people started living longer and better.

"Most people have been looking for an explanation for health change among the old in current conditions," Crimmins said. "We're saying that part of the roots of health in old age lie in childhood. That is what makes this study different because we started looking at the person and their living conditions at a muc
'"/>

Contact: Usha Sutliff
sutliff@usc.edu
213-740-0252
University of Southern California
16-Sep-2004


Page: 1 2

Related biology news :

1. Student science contest participation influences study, career choices, alumni say
2. New study shows hope for treating inhalant abuse
3. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
4. Cigarette smoke causes breaks in DNA and defects to a cells chromosomes, Pitt study finds
5. New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
6. Phase II trials of second-generation antisense cancer drug planned following successful early study
7. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
8. Indiana University, EPA to study airborne PCBs
9. K-State, other universities to study how climate affects plant evolution
10. Washington University in St. Louis leads group studying aging process
11. Simian virus 40 not associated with non-Hodgkin lymphoma, study shows

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/24/2017)... The Controller General of Immigration from Maldives Mr. Mohamed Anwar ... the prestigious international IAIR Award for the most innovative high security ePassport ... ... Maldives Immigration Controller General, Mr. ... on the right) have received the IAIR award for the "Most innovative ...
(Date:3/23/2017)... , March 23, 2017 The report "Gesture Recognition ... Biometric), Industry, and Geography - Global Forecast to 2022", published by MarketsandMarkets, the ... a CAGR of 29.63% between 2017 and 2022. ... ... ...
Breaking Biology News(10 mins):
(Date:4/20/2017)... , ... April 20, 2017 , ... NetDimensions appoints Bill ... , With over 20 years of experience in the learning technologies industry, Mastin joins ... company within Learning Technologies Group plc (LTG). At LEO, Mastin served as SVP of ...
(Date:4/20/2017)... ... April 20, 2017 , ... Open Therapeutics ... property (IP) sharing and commercialization model. , The Center for Advancing Innovation helps ... of this effort is bringing the IP to the attention of the entrepreneurial ...
(Date:4/19/2017)... (PRWEB) , ... April 18, 2017 , ... ... 1970s and has been a key device for generating monodisperse droplets of known ... droplet processes and for generating monodisperse solid particles by drying monodisperse droplets. ...
(Date:4/19/2017)... ... April 19, 2017 , ... Nobilis Therapeutics Announces ... Seeks to Leverage Clinical Data in its Upcoming Post Traumatic Stress Disorder Trial , ... 81 patient clinical trial assessing efficacy of its NBTX-001, a xenon-based therapeutic in the ...
Breaking Biology Technology:
Cached News: