HOME >> BIOLOGY >> NEWS
UT Southwestern researchers cite recent advances in underlying causes of rare body-fat disorders

DALLAS March 18, 2004 More than a decade of work conducted by UT Southwestern Medical Center at Dallas researchers has led to a better understanding of the underlying causes of lipodystrophies disorders characterized by the selective loss of fat tissues, resulting in metabolic complications, such as severe diabetes and high blood cholesterol levels.

By gaining a better understanding of the molecular mechanisms that lead to both inherited and acquired lipodystrophies, researchers hope to discover new therapeutic approaches to prevent the loss of fat tissues and prevent or possibly delay the onset of metabolic complications associated with these disorders.

A review article summarizing research spearheaded by scientists at UT Southwestern is published in today's issue of The New England Journal of Medicine.

"We hear about the metabolic complications of obesity all the time, but these complications also occur in disorders of fat cells that cause partial or total loss of fat from the human body the exact opposite of what occurs in obese individuals," said Dr. Abhimanyu Garg, chief of nutrition and metabolic diseases who has been studying patients with lipodystrophies for the past 16 years. "These disorders have not been widely recognized."

Recently, many HIV-infected patients being treated with a class of drugs known as protease inhibitors have developed lipodystrophies, which has raised awareness of these rare disorders.

Improved knowledge of these disorders will have implications to understanding more prevalent disorders that occur as a result of obesity, like diabetes, which affects more than 16 million Americans, Dr. Garg said.

"What we're learning from treating patients with lipodystrophies may also be applicable to obese patients with abnormal fat distribution, who are more prone to complications," Dr. Garg said. "All of these patients are predisposed to diabetes. Some of these patients even develop d
'"/>

Contact: Amy Shields
amy.shields@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
17-Mar-2004


Page: 1 2 3

Related biology news :

1. UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
2. UT Southwestern biochemist honored with NIH Directors Pioneer Award
3. RSV can increase the risk of asthma, UT Southwestern researchers find
4. Searle Scholars program awards $240,000 to UT Southwestern researcher
5. Two molecules work together to aid transport of immune cells, UT Southwestern researchers find
6. Biochemist becomes 15th UT Southwestern faculty member serving on National Academy of Sciences
7. UT Southwestern researchers reveal mechanisms of smooth-muscle contraction
8. Fetal lungs provide a signal initiating labor, UT Southwestern researchers find
9. UT Southwestern researchers discover link that could aid in treatment of kidney cyst diseases
10. UT Southwestern research halts narcolepsy symptoms
11. UT Southwestern researchers identify gene as essential for vascular smooth muscle development

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/27/2019)... ... August 27, 2019 , ... e3 Diagnostics, the nation’s ... it has partnered with Bertec, a leading manufacturer of force measurement devices for ... a full line of clinical systems for both assessment and treatment of balance ...
(Date:8/23/2019)... ... August 22, 2019 , ... R121 solidifies its place within ... of 2018. Along with the name change, this rebranding includes a comprehensive redesign ... create a cohesive brand that blended our core foundation of genuine ‘one-to-one’ relationships ...
(Date:8/15/2019)... LONDON (PRWEB) , ... August 15, 2019 , ... ... launch of their Food and Agriculture practice, a new unit dedicated to building 100 ... in sustainable nutrition, raw materials and supply chains. , Deep Science Ventures was ...
Breaking Biology News(10 mins):
(Date:8/14/2019)... ... August 13, 2019 , ... ... focus on prepackaged mobile phases for QC laboratories. After gaining a few significant ... laboratory sciences approach into a valued supplier of manufacturing processing solutions, including reagents ...
(Date:8/6/2019)... ... 2019 , ... Shoreline Biome, a microbiome research ... has announced partnerships with six international distributors. , The distributors will sell ... Australia, Benelux, Indonesia, Korea, Malaysia, Myanmar, New Zealand, Singapore, the United Kingdom, and ...
(Date:7/30/2019)... ... July 30, 2019 , ... ... building and cooking events company. Not only has the company already hosted many ... offering Private Cooking Parties to its guests. , With Lajollacooks4u’s Private Cooking Parties, ...
(Date:7/19/2019)... ... July 18, 2019 , ... World renowned ... be joining forces with California-based charity Coalition Duchenne for its 9th Annual Expedition ... raises awareness and funding for Duchenne muscular dystrophy and was founded by Sabahan ...
Breaking Biology Technology:
Cached News: