HOME >> BIOLOGY >> NEWS
UT Southwestern researchers cite recent advances in underlying causes of rare body-fat disorders

DALLAS March 18, 2004 More than a decade of work conducted by UT Southwestern Medical Center at Dallas researchers has led to a better understanding of the underlying causes of lipodystrophies disorders characterized by the selective loss of fat tissues, resulting in metabolic complications, such as severe diabetes and high blood cholesterol levels.

By gaining a better understanding of the molecular mechanisms that lead to both inherited and acquired lipodystrophies, researchers hope to discover new therapeutic approaches to prevent the loss of fat tissues and prevent or possibly delay the onset of metabolic complications associated with these disorders.

A review article summarizing research spearheaded by scientists at UT Southwestern is published in today's issue of The New England Journal of Medicine.

"We hear about the metabolic complications of obesity all the time, but these complications also occur in disorders of fat cells that cause partial or total loss of fat from the human body the exact opposite of what occurs in obese individuals," said Dr. Abhimanyu Garg, chief of nutrition and metabolic diseases who has been studying patients with lipodystrophies for the past 16 years. "These disorders have not been widely recognized."

Recently, many HIV-infected patients being treated with a class of drugs known as protease inhibitors have developed lipodystrophies, which has raised awareness of these rare disorders.

Improved knowledge of these disorders will have implications to understanding more prevalent disorders that occur as a result of obesity, like diabetes, which affects more than 16 million Americans, Dr. Garg said.

"What we're learning from treating patients with lipodystrophies may also be applicable to obese patients with abnormal fat distribution, who are more prone to complications," Dr. Garg said. "All of these patients are predisposed to diabetes. Some of these patients even develop d
'"/>

Contact: Amy Shields
amy.shields@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
17-Mar-2004


Page: 1 2 3

Related biology news :

1. UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
2. UT Southwestern biochemist honored with NIH Directors Pioneer Award
3. RSV can increase the risk of asthma, UT Southwestern researchers find
4. Searle Scholars program awards $240,000 to UT Southwestern researcher
5. Two molecules work together to aid transport of immune cells, UT Southwestern researchers find
6. Biochemist becomes 15th UT Southwestern faculty member serving on National Academy of Sciences
7. UT Southwestern researchers reveal mechanisms of smooth-muscle contraction
8. Fetal lungs provide a signal initiating labor, UT Southwestern researchers find
9. UT Southwestern researchers discover link that could aid in treatment of kidney cyst diseases
10. UT Southwestern research halts narcolepsy symptoms
11. UT Southwestern researchers identify gene as essential for vascular smooth muscle development

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/16/2019)... ... June 14, 2019 , ... Emtec, Inc.®, ... deliver a joint presentation with Versiti’s CIO at the Healthcare Industry User ... Shingle Creek Resort. , Versiti Vice President and Chief Information Officer, Lynne Briggs, ...
(Date:6/13/2019)... ... 13, 2019 , ... KICVentures announced today its plans to host ... Pain Management-Driven ASC Conference in Chicago on Thursday, June 13th at 6:30 pm. The ... IL in the 3rd floor Ticino Hospitality room in space #74T. , The event ...
(Date:6/11/2019)... ... June 12, 2019 , ... With a rapidly growing customer ... the Geneious Biologics platform as a premium hub for bioinformatics and computer programming ... “The Geneious team has done an excellent job accommodating our specific data, resulting ...
Breaking Biology News(10 mins):
(Date:5/22/2019)... ... May 22, 2019 , ... Artemis (formerly Agrilyst), ... million Series A funding round co-led by Astanor Ventures and Talis ... Fund and iSelect Fund . The company has raised $11.75m to date ...
(Date:5/14/2019)... ... May 13, 2019 , ... Leak Detection ... for the Pharmaceutical, Biotechnology, Medical Device and Food Packaging Industries’ is excited to ... aims to improve LDA’s ability to communicate directly with the marketplace; serving as ...
(Date:5/4/2019)... ... May 03, 2019 , ... More than three thousand people ... the scientist and ufologist Urandir Fernandes de Oliveira, last Thursday (25), during the ... of some research carried out by the association, in partnership with scientists from ...
(Date:5/2/2019)... ... ... Stay on top of current hot topics through free webinars presented by ... is free, so be sure to register today to save your place! Participate in ... see our upcoming webinars: , CLINICAL TRIALS , May 7 – Oncology Clinical Trials ...
Breaking Biology Technology:
Cached News: