HOME >> BIOLOGY >> NEWS
UT Southwestern researchers cite recent advances in underlying causes of rare body-fat disorders

DALLAS March 18, 2004 More than a decade of work conducted by UT Southwestern Medical Center at Dallas researchers has led to a better understanding of the underlying causes of lipodystrophies disorders characterized by the selective loss of fat tissues, resulting in metabolic complications, such as severe diabetes and high blood cholesterol levels.

By gaining a better understanding of the molecular mechanisms that lead to both inherited and acquired lipodystrophies, researchers hope to discover new therapeutic approaches to prevent the loss of fat tissues and prevent or possibly delay the onset of metabolic complications associated with these disorders.

A review article summarizing research spearheaded by scientists at UT Southwestern is published in today's issue of The New England Journal of Medicine.

"We hear about the metabolic complications of obesity all the time, but these complications also occur in disorders of fat cells that cause partial or total loss of fat from the human body the exact opposite of what occurs in obese individuals," said Dr. Abhimanyu Garg, chief of nutrition and metabolic diseases who has been studying patients with lipodystrophies for the past 16 years. "These disorders have not been widely recognized."

Recently, many HIV-infected patients being treated with a class of drugs known as protease inhibitors have developed lipodystrophies, which has raised awareness of these rare disorders.

Improved knowledge of these disorders will have implications to understanding more prevalent disorders that occur as a result of obesity, like diabetes, which affects more than 16 million Americans, Dr. Garg said.

"What we're learning from treating patients with lipodystrophies may also be applicable to obese patients with abnormal fat distribution, who are more prone to complications," Dr. Garg said. "All of these patients are predisposed to diabetes. Some of these patients even develop d
'"/>

Contact: Amy Shields
amy.shields@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
17-Mar-2004


Page: 1 2 3

Related biology news :

1. UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
2. UT Southwestern biochemist honored with NIH Directors Pioneer Award
3. RSV can increase the risk of asthma, UT Southwestern researchers find
4. Searle Scholars program awards $240,000 to UT Southwestern researcher
5. Two molecules work together to aid transport of immune cells, UT Southwestern researchers find
6. Biochemist becomes 15th UT Southwestern faculty member serving on National Academy of Sciences
7. UT Southwestern researchers reveal mechanisms of smooth-muscle contraction
8. Fetal lungs provide a signal initiating labor, UT Southwestern researchers find
9. UT Southwestern researchers discover link that could aid in treatment of kidney cyst diseases
10. UT Southwestern research halts narcolepsy symptoms
11. UT Southwestern researchers identify gene as essential for vascular smooth muscle development

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... (NYSE: IBM ) is introducing several innovative partner startups ... collaboration between startups and global businesses, taking place in ... nine startups will showcase the solutions they have built with ... France is one of the ... percent increase in the number of startups created between 2012 ...
(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
(Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... platform specifically designed for life science researchers to analyze and interpret datasets, ... Franklin, who made a major contribution to the discovery of the double-helix ...
(Date:10/11/2017)... ... ... Personal eye wash is a basic first aid supply for any work environment, but most ... you rinse first if a dangerous substance enters both eyes? It’s one less decision, and ... unique dual eye piece. , “Whether its dirt and debris, or an acid or alkali, ...
(Date:10/11/2017)... , Oct. 11, 2017  VMS BioMarketing, a leading ... a nationwide oncology Clinical Nurse Educator (CNE) network, which will ... need for communication among health care professionals to enhance the ... nurses, office staff, and other health care professionals to help ... breast cancer. ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... implantation and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... and maternal age to IVF success. , After comparing the results from the ...
Breaking Biology Technology:
Cached News: