HOME >> BIOLOGY >> NEWS
UT Southwestern researchers say overdoses of acetaminophen cause most cases of acute liver failure

at 39 percent of cases were from acetaminophen overdose, and they also discovered that 13 percent were from idiosyncratic drug reactions; 12 percent were from viral hepatitis A and B; and 17 percent were of indeterminate cause.

"Acetaminophen is quite safe when taken accordingly to package recommendations," Lee said. "Eighty-three percent of our patients who developed acute liver failure had exceeded the daily maximum recommended dose of four grams."

While 68 percent of patients with acute liver failure related to acetaminophen overdose recovered with supportive care and 6 percent required transplantation, only 25 percent of patients with idiosyncratic drug reactions recovered and more than 50 percent required transplants once their nervous systems were damaged by liver function failure.

In 1997, Lee formed a consortium of liver centers, called the Acute Liver Failure Study Group, to increase research in this area. The scientific collaboration has made it possible for investigators to study the disease in greater depth.

Two former UT Southwestern researchers Drs. George Ostapowicz and Frank Schiodt also contributed to the study. Other collaborators are from Baylor University Medical Center; the Mayo Clinic; Gold Coast Hospital in Southport, Australia; Northwestern University; and the universities of Michigan, Washington, California-Los Angeles, California-San Francisco, Nebraska, and Pittsburgh.


'"/>

Contact: Susan Morrison
Susan.Morrison@UTSouthwestern.edu
214-648-3404
UT Southwestern Medical Center
16-Dec-2002


Page: 1 2

Related biology news :

1. UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
2. UT Southwestern biochemist honored with NIH Directors Pioneer Award
3. RSV can increase the risk of asthma, UT Southwestern researchers find
4. Searle Scholars program awards $240,000 to UT Southwestern researcher
5. Two molecules work together to aid transport of immune cells, UT Southwestern researchers find
6. Biochemist becomes 15th UT Southwestern faculty member serving on National Academy of Sciences
7. UT Southwestern researchers reveal mechanisms of smooth-muscle contraction
8. Fetal lungs provide a signal initiating labor, UT Southwestern researchers find
9. UT Southwestern researchers cite recent advances in underlying causes of rare body-fat disorders
10. UT Southwestern researchers discover link that could aid in treatment of kidney cyst diseases
11. UT Southwestern research halts narcolepsy symptoms

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/20/2017)... 20, 2017 At this year,s CeBIT Chancellor Dr. ... manufacturer DERMALOG. The Chancellor came to the DERMALOG stand together with the ... year,s CeBIT partner country. At the largest German biometrics company the two ... face and iris recognition as well as DERMALOGĀ“s multi-biometrics system.   ... ...
(Date:3/13/2017)... , March 13, 2017 Future of security: Biometric ... ... DERMALOGs Face Matching enables to match face pictures ... the basis to identify individuals. (PRNewsFoto/Dermalog Identification Systems) ... DERMALOG,s "Face Matching" is the fastest software for biometric Face ...
(Date:3/7/2017)... Brandwatch , the leading social intelligence company, today announces that ... uncover insights to support its reporting, help direct future campaigns, and ... youth charity will be using Brandwatch Analytics social listening and analytics ... of the topics and issues that are a priority for its ... "Until recently ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... 2017 NetworkNewsWire Editorial Coverage  ... Cancer remains one ... on health care systems, in terms of costs and resources. ... does the development of innovative and efficient therapies that demonstrate ... many types of cancer treatments, a growing number of patients ...
(Date:3/22/2017)... TARRYTOWN, N.Y. , March 22, 2017 Regeneron ... among the Regeneron Genetics Center (RGC), U.K. Biobank and GSK ... in the U.K. Biobank resource. The initiative will enable researchers ... of new medicines for a wide range of serious and ... ...
(Date:3/22/2017)... , March 22, 2017 Oramed Pharmaceuticals ... www.oramed.com ), a clinical-stage ... drug delivery systems, announced today that Dr. ... deliver a presentation titled, "Oral Insulin for Diabetes ... Cambridge Healthtech Institute,s Oligonucleotide and Peptide Therapeutics (OPT) Boston Conference ...
(Date:3/22/2017)... --  Boston Biomedical , an industry leader in the ... stemness pathways, today announced its Board of Directors has ... Officer, effective April 24, 2017. Ms. ... FACP, who has led Boston Biomedical since he founded ... Biomedical has grown from a "garage startup" without technology ...
Breaking Biology Technology:
Cached News: