HOME >> BIOLOGY >> NEWS
UT Southwestern researchers say overdoses of acetaminophen cause most cases of acute liver failure

at 39 percent of cases were from acetaminophen overdose, and they also discovered that 13 percent were from idiosyncratic drug reactions; 12 percent were from viral hepatitis A and B; and 17 percent were of indeterminate cause.

"Acetaminophen is quite safe when taken accordingly to package recommendations," Lee said. "Eighty-three percent of our patients who developed acute liver failure had exceeded the daily maximum recommended dose of four grams."

While 68 percent of patients with acute liver failure related to acetaminophen overdose recovered with supportive care and 6 percent required transplantation, only 25 percent of patients with idiosyncratic drug reactions recovered and more than 50 percent required transplants once their nervous systems were damaged by liver function failure.

In 1997, Lee formed a consortium of liver centers, called the Acute Liver Failure Study Group, to increase research in this area. The scientific collaboration has made it possible for investigators to study the disease in greater depth.

Two former UT Southwestern researchers Drs. George Ostapowicz and Frank Schiodt also contributed to the study. Other collaborators are from Baylor University Medical Center; the Mayo Clinic; Gold Coast Hospital in Southport, Australia; Northwestern University; and the universities of Michigan, Washington, California-Los Angeles, California-San Francisco, Nebraska, and Pittsburgh.


'"/>

Contact: Susan Morrison
Susan.Morrison@UTSouthwestern.edu
214-648-3404
UT Southwestern Medical Center
16-Dec-2002


Page: 1 2

Related biology news :

1. UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
2. UT Southwestern biochemist honored with NIH Directors Pioneer Award
3. RSV can increase the risk of asthma, UT Southwestern researchers find
4. Searle Scholars program awards $240,000 to UT Southwestern researcher
5. Two molecules work together to aid transport of immune cells, UT Southwestern researchers find
6. Biochemist becomes 15th UT Southwestern faculty member serving on National Academy of Sciences
7. UT Southwestern researchers reveal mechanisms of smooth-muscle contraction
8. Fetal lungs provide a signal initiating labor, UT Southwestern researchers find
9. UT Southwestern researchers cite recent advances in underlying causes of rare body-fat disorders
10. UT Southwestern researchers discover link that could aid in treatment of kidney cyst diseases
11. UT Southwestern research halts narcolepsy symptoms

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/11/2016)... , March 11, 2016 http://www.apimages.com ) - ... reference: Picture is available at AP Images ( http://www.apimages.com ) - ... will be used to produce the new refugee identity cards. DERMALOG ... innovations, at CeBIT in Hanover next week.   ... DERMALOG will be used to produce the new refugee identity cards. ...
(Date:3/9/2016)... YORK , March 9, 2016 This ... and future states of the RNA Sequencing (RNA Seq) ... segments such as instruments, tools and reagents, data analysis, ... Analyze various segments of the RNA-Sequencing market such as ... services Identify the main factors affecting each segment and ...
(Date:3/3/2016)... Calif. , March 3, 2016  FlexTech, a ... the categories of Innovation, Research & Development, Leadership in ... Leadership. This is the 9 th year of ... group of companies and individuals from past years ... based on a pre-described set of criteria, by a ...
Breaking Biology News(10 mins):
(Date:5/23/2016)... Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), ... Board of Directors has approved the payment of a quarterly ... The cash dividend of $0.24 per share ... stockholders of record as of the close of business on ... approval of the Board of Directors and may be adjusted ...
(Date:5/23/2016)... , May 23, 2016 - Leading CRO,s ... - Frontage Implement a Single Platform to Manage End-to-end ... Traceability Within the Bioanalytical lab Frontage Laboratories, a full-service ... States and China , has selected ... facilities. In addition to serving as the global electronic lab notebook ...
(Date:5/23/2016)... ... May 23, 2016 , ... Foresight Institute , ... the winners for the 2015 Foresight Institute Feynman Prizes. , These prestigious ... categories, one for experiment and the other for theory in nanotechnology. Prof. Markus ...
(Date:5/20/2016)... San Diego, CA (PRWEB) , ... May 20, 2016 , ... ... announce that 10 of its most experienced veterinary clients have treated over 100 of ... this cutting edge technology to provide the highest level of care for their patients. ...
Breaking Biology Technology:
Cached News: