UT Southwestern scientist receives international award for lipid research

DALLAS Dr. David J. Mangelsdorf, professor of pharmacology and biochemistry at UT Southwestern Medical Center at Dallas and an associate investigator in the university's Howard Hughes Medical Institute, has been awarded Germany's highly respected Heinrich Wieland Prize for his research on lipids.

The prestigious international science award is given annually to one individual for research in the fields of biochemistry, chemistry and physiology of fats and lipids and its clinical importance.

Dr. Mangelsdorf's research focuses on the mechanisms of nuclear receptor proteins that serve as sensors in protecting human cells against unusually high and possibly toxic levels of lipids, such as cholesterol and fatty acids. These lipid-sensing proteins play a central role in the maintenance of physiological levels of lipids consumed with food. Dr. Mangelsdorf's work signifies an important contribution to the elucidation of the mechanism that the body uses to restore the balance following an increase in cholesterol levels.

Three other UT Southwestern scientists have received the Wieland Prize since its inception in 1963.

Nobel laureates Drs. Michael Brown and Joseph Goldstein claimed the award in 1974 for their research in lipoprotein receptors and the genetic control of cholesterol metabolism. They shared the Nobel Prize in physiology or medicine in 1985 for their discovery of the underlying mechanisms of cholesterol metabolism, which led to the development of statin drugs now used by 13 million Americans to treat high cholesterol.

Dr. John Dietschy, professor of internal medicine, received the Wieland Prize in 1983 while he was chief of gastroenterology at UT Southwestern for his research into the regulation of cholesterol balance in tissues.

"It is quite an honor to be considered in the running for this award, next to these other great names, and even more to receive it," said Dr. Mangelsdorf. "It reflects the great stature o

Contact: Donna Steph Hansard
UT Southwestern Medical Center

Page: 1 2 3

Related biology news :

1. UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
2. UT Southwestern biochemist honored with NIH Directors Pioneer Award
3. RSV can increase the risk of asthma, UT Southwestern researchers find
4. Searle Scholars program awards $240,000 to UT Southwestern researcher
5. Two molecules work together to aid transport of immune cells, UT Southwestern researchers find
6. Biochemist becomes 15th UT Southwestern faculty member serving on National Academy of Sciences
7. UT Southwestern researchers reveal mechanisms of smooth-muscle contraction
8. Fetal lungs provide a signal initiating labor, UT Southwestern researchers find
9. UT Southwestern researchers cite recent advances in underlying causes of rare body-fat disorders
10. UT Southwestern researchers discover link that could aid in treatment of kidney cyst diseases
11. UT Southwestern research halts narcolepsy symptoms

Post Your Comments:

(Date:6/3/2016)... , June 3, 2016 ... von Nepal hat ... Lieferung hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, Registrierung ... in der Produktion und Implementierung von Identitätsmanagementlösungen. ... Ausschreibung im Januar teilgenommen, aber Decatur wurde ...
(Date:5/24/2016)... superior patient care by providing unparalleled technology to leaders of the medical imaging industry. ... recently added to the range of products distributed by Ampronix. Photo - ... ... ... ...
(Date:5/3/2016)... May 3, 2016  Neurotechnology, a provider of ... MegaMatcher Automated Biometric Identification System (ABIS) , a ... projects. MegaMatcher ABIS can process multiple complex biometric ... combination of fingerprint, face or iris biometrics. It ... and MegaMatcher Accelerator , which have ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... --  Ginkgo Bioworks , a leading organism design ... awarded as one of the World Economic Forum,s ... innovative companies. Ginkgo Bioworks is engineering biology to ... in the nutrition, health and consumer goods sectors. ... including Fortune 500 companies to design microbes for ...
(Date:6/24/2016)... SAN DIEGO , June 24, 2016 /PRNewswire/ ... that more sensitively detects cancers susceptible to PARP ... individual circulating tumor cells (CTCs). The new test ... of HRD-targeted therapeutics in multiple cancer types. ... therapies targeting DNA damage response pathways, including PARP, ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Researchers at ... most commonly-identified miRNAs in people with peritoneal or pleural mesothelioma. Their findings are the ... read it now. , Diagnostic biomarkers are signposts in the blood, lung fluid ...
(Date:6/23/2016)... WI (PRWEB) , ... June 23, 2016 , ... ... supplements, is pleased to announce the launch of their brand, UP4™ Probiotics, into ... for over 35 years, is proud to add Target to its list of ...
Breaking Biology Technology:
Cached News: