HOME >> BIOLOGY >> NEWS
UT Southwestern scientists explain how the injured brain remodels itself

DALLAS Nov. 1, 2001 - Researchers at UT Southwestern Medical Center at Dallas have begun to reveal the cellular mechanisms critical for restoring brain functions after traumatic injuries a step that could lead to effective treatments of paralysis and other brain and spinal-cord damage.

The study indicated that the injured brains long-observed restorative powers at least partially derive from generating waves of adult-neural stem cells, or specialized precursors, to develop into critically needed replacement neurons and astrocytes. Neurons, the basic building blocks of the nervous system, and astrocytic cells, which provide metabolic functions between neurons and blood vessels, are crucial to restoring or remodeling damaged brain and spinal-cord tissue.

Published in the Nov. 1 issue of the Journal of Neuroscience Research, the study involving adult mice showed that following traumatic brain injury, the brains stem-cell proliferation continues at a rapid pace and persists over a much longer time than expected, both at the injury site and even in the most-distant areas affected by the injury, said Dr. Steven G. Kernie, assistant professor of pediatrics and lead researcher.

The findings suggest that manipulating the expression of stem-cell regulators might accelerate or prolong the regeneration of neurons in humans, said Kernie, who collaborated with Dr. Luis F. Parada, director of the Center for Developmental Biology and the Kent Waldrep Foundation Center for Basic Research on Nerve Growth and Regeneration.

We wanted to answer some basic questions about the persistence of neural stem cells proliferating into adulthood, Kernie said. Our study of traumatic brain injuries in adult mice found that natures own restorative powers are more extensive than previously thought. Perhaps even more exciting, we found that the regenerative powers are widespread, not just in the immediate area of the injury. Though using mice, our study raises the pos
'"/>

Contact: Worth Wren Jr.
Worth.Wren@UTSouthwestern.edu
214-648-3404
UT Southwestern Medical Center
1-Nov-2001


Page: 1 2

Related biology news :

1. UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
2. UT Southwestern biochemist honored with NIH Directors Pioneer Award
3. RSV can increase the risk of asthma, UT Southwestern researchers find
4. Searle Scholars program awards $240,000 to UT Southwestern researcher
5. Two molecules work together to aid transport of immune cells, UT Southwestern researchers find
6. Biochemist becomes 15th UT Southwestern faculty member serving on National Academy of Sciences
7. UT Southwestern researchers reveal mechanisms of smooth-muscle contraction
8. Fetal lungs provide a signal initiating labor, UT Southwestern researchers find
9. UT Southwestern researchers cite recent advances in underlying causes of rare body-fat disorders
10. UT Southwestern researchers discover link that could aid in treatment of kidney cyst diseases
11. UT Southwestern research halts narcolepsy symptoms

Post Your Comments:
(Date:10/29/2014)... a consequence of chemotherapy will benefit from a major ... that prevents hair loss. , The research is being ... cooling manufacturing company, Paxman Coolers, of Fenay Bridge, Huddersfield, ... of Huddersfield. , The research will be led by ... the pharmacology of cancer treatment, which he will use ...
(Date:10/29/2014)... Beaverton, OR) New research presented at the ... in Houston, TX showed for the first time ... in women using a readily available nutritional supplement, ... by Dr. Judith A. Smith, Pharm.D., associate professor ... Sciences at The University of Texas Health Science ...
(Date:10/29/2014)... factors, both genetic and environmental, have been blamed ... schizophrenia. Some, such as a family history of ... with Toxoplasma gondii , a parasite transmitted ... still viewed with skepticism. , A new study ... epidemiology at the University of Pennsylvania,s School of ...
Breaking Biology News(10 mins):New technology on the way to aid cancer suffers who lose their hair after chemotherapy 2HPV infections in women eradicated by AHCC, Japanese mushroom extract 2Penn vet professor investigates parasite-schizophrenia connection 2Penn vet professor investigates parasite-schizophrenia connection 3
(Date:10/31/2014)... 30, 2014 Two separate delegations ... hosted by Charm Sciences at its Andover, Massachusetts ... in the US, the participants discussed international systems ... management, and process verification, and received hands-on technical ... was the first visit to the United States ...
(Date:10/31/2014)... The report "Dairy Alternative (Beverage) Market ... Sweetened, Unsweetened), Channel (Supermarket, Health Store, Pharmacy, Convenience ... to 2018," defines and segments the dairy alternative ... revenue and volume for plant-based dairy alternative beverages. ... $14 Billion by 2018 with the Asia-Pacific region ...
(Date:10/31/2014)... Fla. , Oct. 31, 2014  Tavistock ... owned by Tavistock Group, celebrated the groundbreaking of the ... Medical City. The 92,000-square-foot, three-story ... Central Florida designed specifically for ... in the heart of the 650-acre Lake Nona ...
(Date:10/30/2014)... 30, 2014  Ardelyx, Inc. (NASDAQ: ... cardio-renal, gastrointestinal and metabolic diseases, today announced that ... on Thursday, November 6, 2014. Following the announcement, ... conference call and webcast at 4:30pm ET to ... business update. The live webcast can ...
Breaking Biology Technology:Charm Sciences Hosts Executives from Latin America for Dairy Safety Executive Seminar 2Dairy Alternative Beverage Market Projected to Reach $14 Billion by 2018 - Report by MarketsandMarkets 2Dairy Alternative Beverage Market Projected to Reach $14 Billion by 2018 - Report by MarketsandMarkets 3Dairy Alternative Beverage Market Projected to Reach $14 Billion by 2018 - Report by MarketsandMarkets 4GuideWell Innovation Center Groundbreaking Hosted by Tavistock Development Company at Lake Nona Medical City 2GuideWell Innovation Center Groundbreaking Hosted by Tavistock Development Company at Lake Nona Medical City 3Ardelyx to Report Third Quarter 2014 Financial Results on November 6, 2014 2
Cached News: