HOME >> BIOLOGY >> NEWS
UT Southwestern scientists explain how the injured brain remodels itself

DALLAS Nov. 1, 2001 - Researchers at UT Southwestern Medical Center at Dallas have begun to reveal the cellular mechanisms critical for restoring brain functions after traumatic injuries a step that could lead to effective treatments of paralysis and other brain and spinal-cord damage.

The study indicated that the injured brains long-observed restorative powers at least partially derive from generating waves of adult-neural stem cells, or specialized precursors, to develop into critically needed replacement neurons and astrocytes. Neurons, the basic building blocks of the nervous system, and astrocytic cells, which provide metabolic functions between neurons and blood vessels, are crucial to restoring or remodeling damaged brain and spinal-cord tissue.

Published in the Nov. 1 issue of the Journal of Neuroscience Research, the study involving adult mice showed that following traumatic brain injury, the brains stem-cell proliferation continues at a rapid pace and persists over a much longer time than expected, both at the injury site and even in the most-distant areas affected by the injury, said Dr. Steven G. Kernie, assistant professor of pediatrics and lead researcher.

The findings suggest that manipulating the expression of stem-cell regulators might accelerate or prolong the regeneration of neurons in humans, said Kernie, who collaborated with Dr. Luis F. Parada, director of the Center for Developmental Biology and the Kent Waldrep Foundation Center for Basic Research on Nerve Growth and Regeneration.

We wanted to answer some basic questions about the persistence of neural stem cells proliferating into adulthood, Kernie said. Our study of traumatic brain injuries in adult mice found that natures own restorative powers are more extensive than previously thought. Perhaps even more exciting, we found that the regenerative powers are widespread, not just in the immediate area of the injury. Though using mice, our study raises the pos
'"/>

Contact: Worth Wren Jr.
Worth.Wren@UTSouthwestern.edu
214-648-3404
UT Southwestern Medical Center
1-Nov-2001


Page: 1 2

Related biology news :

1. UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
2. UT Southwestern biochemist honored with NIH Directors Pioneer Award
3. RSV can increase the risk of asthma, UT Southwestern researchers find
4. Searle Scholars program awards $240,000 to UT Southwestern researcher
5. Two molecules work together to aid transport of immune cells, UT Southwestern researchers find
6. Biochemist becomes 15th UT Southwestern faculty member serving on National Academy of Sciences
7. UT Southwestern researchers reveal mechanisms of smooth-muscle contraction
8. Fetal lungs provide a signal initiating labor, UT Southwestern researchers find
9. UT Southwestern researchers cite recent advances in underlying causes of rare body-fat disorders
10. UT Southwestern researchers discover link that could aid in treatment of kidney cyst diseases
11. UT Southwestern research halts narcolepsy symptoms

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/22/2016)... American College of Medical Genetics and Genomics was once again ... of the fastest-growing trade shows during the Fastest 50 Awards ... Las Vegas . Winners are ... of the following categories: net square feet of paid exhibit ... 2015 ACMG Annual Meeting was ranked 23 out of 50 ...
(Date:6/22/2016)... 2016 On Monday, the Department of Homeland ... share solutions for the Biometric Exit Program. The Request ... Protection (CBP), explains that CBP intends to add biometrics ... the United States , in order to deter ... Logo - http://photos.prnewswire.com/prnh/20160622/382209LOGO ...
(Date:6/20/2016)... 20, 2016 Securus Technologies, a leading ... for public safety, investigation, corrections and monitoring announced ... it has secured the final acceptance by all ... Managed Access Systems (MAS) installed. Furthermore, Securus will ... be installed by October, 2016. MAS distinguishes between ...
Breaking Biology News(10 mins):
(Date:12/7/2016)... 7, 2016 /PRNewswire/ - OncoQuest Inc. ("OncoQuest"), a ... of immunotherapeutic products for the treatment of cancer, ... Antibody Manufacturing Development Program with Cytovance Biologics ( ... its oregovomab antibody product. Supported by recent positive ... study in ovarian cancer patients, OncoQuest has engaged ...
(Date:12/7/2016)...  Vyriad Inc. announced today the appointment of ... Directors. "We are delighted to welcome Al ... develop our oncolytic viruses as the next generation of ... , MD, PhD, CEO of Vyriad. "Al and his ... passion for making a difference for cancer patients—their philanthropy ...
(Date:12/7/2016)... (PRWEB) , ... December 07, 2016 , ... ... treatment and resource recovery solutions for industrial facilities, today announced that one of ... the first to use Cambrian’s novel water-energy purchase agreement (WEPA). Under the WEPA, ...
(Date:12/6/2016)... Dec. 6, 2016 The American Botanical Council ... of arnica ( Arnica montana ) through ABC,s ... HerbMedPro database, a comprehensive, interactive online ... clinical research data on the uses and health ... Naturopathica, a wellness company with healing arts ...
Breaking Biology Technology:
Cached News: