HOME >> BIOLOGY >> NEWS
UT Southwestern scientists explain how the injured brain remodels itself

DALLAS Nov. 1, 2001 - Researchers at UT Southwestern Medical Center at Dallas have begun to reveal the cellular mechanisms critical for restoring brain functions after traumatic injuries a step that could lead to effective treatments of paralysis and other brain and spinal-cord damage.

The study indicated that the injured brains long-observed restorative powers at least partially derive from generating waves of adult-neural stem cells, or specialized precursors, to develop into critically needed replacement neurons and astrocytes. Neurons, the basic building blocks of the nervous system, and astrocytic cells, which provide metabolic functions between neurons and blood vessels, are crucial to restoring or remodeling damaged brain and spinal-cord tissue.

Published in the Nov. 1 issue of the Journal of Neuroscience Research, the study involving adult mice showed that following traumatic brain injury, the brains stem-cell proliferation continues at a rapid pace and persists over a much longer time than expected, both at the injury site and even in the most-distant areas affected by the injury, said Dr. Steven G. Kernie, assistant professor of pediatrics and lead researcher.

The findings suggest that manipulating the expression of stem-cell regulators might accelerate or prolong the regeneration of neurons in humans, said Kernie, who collaborated with Dr. Luis F. Parada, director of the Center for Developmental Biology and the Kent Waldrep Foundation Center for Basic Research on Nerve Growth and Regeneration.

We wanted to answer some basic questions about the persistence of neural stem cells proliferating into adulthood, Kernie said. Our study of traumatic brain injuries in adult mice found that natures own restorative powers are more extensive than previously thought. Perhaps even more exciting, we found that the regenerative powers are widespread, not just in the immediate area of the injury. Though using mice, our study raises the pos
'"/>

Contact: Worth Wren Jr.
Worth.Wren@UTSouthwestern.edu
214-648-3404
UT Southwestern Medical Center
1-Nov-2001


Page: 1 2

Related biology news :

1. UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
2. UT Southwestern biochemist honored with NIH Directors Pioneer Award
3. RSV can increase the risk of asthma, UT Southwestern researchers find
4. Searle Scholars program awards $240,000 to UT Southwestern researcher
5. Two molecules work together to aid transport of immune cells, UT Southwestern researchers find
6. Biochemist becomes 15th UT Southwestern faculty member serving on National Academy of Sciences
7. UT Southwestern researchers reveal mechanisms of smooth-muscle contraction
8. Fetal lungs provide a signal initiating labor, UT Southwestern researchers find
9. UT Southwestern researchers cite recent advances in underlying causes of rare body-fat disorders
10. UT Southwestern researchers discover link that could aid in treatment of kidney cyst diseases
11. UT Southwestern research halts narcolepsy symptoms

Post Your Comments:
(Date:4/15/2014)... Biologists at UC San Diego have succeeded in ... hormone responsible for growth and resistance to drought. ... studies to determine how the hormone helps plants ... by the continuing increase in the atmosphere,s carbon ... achievement appears in the April 15 issue of ...
(Date:4/15/2014)... Looking at the question of how social behavior has ... universities in Mainz and Basel have gained new insights ... simply compete for food. Rather the siblings share what ... absent," explained Dr. Jol Meunier of the Evolutionary Biology ... University of Mainz (JGU). The team of biologists from ...
(Date:4/15/2014)... (April 15, 2014) The American Association of Anatomists ... All awards will be presented during the Closing ... Hotel on Tuesday, April 29th at 7:30 p.m. during ... , The 2014 award winners are: , ... PhD, of the Icahn School of Medicine at Mount ...
Breaking Biology News(10 mins):Biologists develop nanosensors to visualize movements and distribution of plant hormone 2Sibling cooperation in earwig families gives clues to early evolution of social behavior 2American Association of Anatomists 2014 award winners 2
(Date:1/15/2014)... January 15, 2014 This webinar ... on nonclinical and clinical safety assessment in biosimilars. ... guide a path for biosimilar drug development, however ... of biosimilarity with regards to quality, safety and ... of biosimilar drug development and registration, development strategies ...
(Date:1/15/2014)... NC (PRWEB) January 15, 2014 ... an enhancement to its Online Web Portal for Life ... now have the ability to specify the subject matter ... nearly 50 life science sub-domains. This will help reduce ... and scientific fields, and decrease the likelihood of error. ...
(Date:1/14/2014)... Doylestown, PA (PRWEB) January 14, 2014 ... – 11 p.m. , Location: Warrington Country Club, 1360 ... Hepatitis B Foundation, the only national nonprofit organization solely ... improving the quality of life for those affected worldwide, ... 11 at Warrington Country Club in Warrington, Pa. ...
(Date:1/14/2014)... York, NY (PRWEB) January 14, 2014 ... initiated coverage of Alliqua, Inc. (OTCQB: ALQA). Alliqua ... and marketing proprietary products to serve the wound ... , In late 2012, Alliqua was restructured ... launched the company’s new strategy to become a ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2DTS Improves Efficiency for Life Science Document Translations 2Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
Cached News: