HOME >> BIOLOGY >> NEWS
UV Skin Damage In A Different Light

Despite all the warnings to avoid exposure to the sun and to wear sunscreen, scientists don't really know how the sun damages our skin. Now, they're a bit closer to the answer.

Two scientists recently discovered that sunlight triggers a harmful reaction when it strikes a molecule in our skin--ironically a molecule once thought to be "nature's sunscreen." The work suggests the science behind the sagging, leathery skin typical of long-term sun worshipers, and may also shed light on how ultraviolet light causes skin cancer.

"We studied a natural component of human skin exposed to ultraviolet light and uncovered a new chemical reaction that may contribute to aging [of the skin] and cancer," said Dr. John Simon, who led the study.

The research will appear in the September 1 issue of the Proceedings of the National Academy of Sciences. The work was conducted at the University of California, San Diego by Dr. John D. Simon (who is now at Duke University), and his graduate student Kerry Hanson (who is now a postdoctoral fellow at the University of Illinois at Urbana-Champaign).

The sun's harmful rays come in two flavors: ultraviolet A and ultraviolet B. Evidence mounts that ultraviolet A and B both play a role in causing skin cancer and photoaging, which is characterized by deep, premature wrinkles, thickened skin, and age spots.

Time, gravity, and heredity notwithstanding, "something like 90 percent of all the visible signs of aging are from ultra-violet sources," said Dr. Kerry Hanson. "Photoaging is not just a cosmetic effect. It destroys the integrity of your skin."

The focus of this study is the sun-sensitive molecule called trans-urocanic acid (t-UA). Formed in the top layer of the skin, t-UA molecules cover our bodies, acting like antennae for light. In the 1950s, urocanic acid was hailed as a "natural sunscreen" because it absorbs ultraviolet B light. It was thus thought to protect against damage by such rays, which can potentially
'"/>

Contact: Alisa Machalek
machalea@nigms.nih.gov
(301) 496-7301
NIH/National Institute of General Medical Sciences
1-Sep-1998


Page: 1 2 3

Related biology news :

1. Damaged genes in aging human brain provide clues to cognitive decline
2. Damage from acid rain pollution is far worse than previously believed
3. Damaged DNA synthesis enzyme shown to cause progressive muscle weakening
4. Damaged spinal cord found to have greater potential for nerve regrowth than thought possible
5. Concern Unfounded About Damage From Vitamin C
6. Enzyme Required To Prolong Life In Worms Identified By Researchers At Columbia; Key Enzyme Appears To Protect Animal Cells From Oxidative Damage
7. UCSF Scientists Report On A Transcription Factor That Could Stimulate Heart Cells To Repair Damage Caused By Heart Attacks Or Birth Defects
8. Jefferson Scientists Find Further Proof Of Damage To The FHIT Gene In Breast Cancers
9. Study Indicates Adolescent Smokers Are More Susceptible To Long-Term DNA Damage From Smoking Than Adults Smokers
10. Spider Venom Stops Stroke Brain Damage
11. Common Respiratory Virus Identified As One Cause Of Heart Muscle Damage That Can Lead To Sudden Death

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Skin Damage Different Light

(Date:4/17/2014)... and pathogens that devastate honeybees in Europe, Asia and ... do not appear to be impacting native honeybee populations ... researchers., The invasive pests include including Nosema microsporidia ... honeybees appear to be resilient to these invasive pests, ... control pests in Europe, Asia and the United States ...
(Date:4/17/2014)... Current Biology on April 17 have discovered ... Brazilian insects, which represent four distinct but related species ... example of an animal with sex-reversed genitalia. , ... animals, Neotrogla is the only example in ... Yoshizawa from Hokkaido University in Japan. , During copulation, ...
(Date:4/17/2014)... Scientists have uncovered a new way the immune system ... aid efforts to use immune cells to treat illness. ... have the immunological equivalent of "neighborhood police" specialized ... single organ, instead of an entire city, the body. ... St. Louis have shown that the liver, skin and ...
Breaking Biology News(10 mins):East African honeybees are safe from invasive pests… for now 2East African honeybees are safe from invasive pests… for now 3In sex-reversed cave insects, females have the penises 2Some immune cells defend only 1 organ 2
(Date:1/15/2014)... SAN JOSE, California , January 15, 2014 ... antibody-drug conjugates for cancer, today announced the appointment of Thomas ... Reynolds has over 20 years, development experience gained in the ... Genetics. "I am delighted to welcome Tom at ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 This webinar ... nonclinical and clinical safety assessment in biosimilars. , Regulatory ... for biosimilar drug development, however the complex nature of ... quality, safety and efficacy extremely challenging. Based on the ...
(Date:1/15/2014)... January 15, 2014 More than 5 ... about 1 in 3 seniors will die with Alzheimer’s ... These jaw-dropping figures have shocked many Americans into looking ... help prevent these tragic age-related cognitive disorders. Jonathan Weisman, ...
(Date:1/15/2014)... The Microcompetition with Foreign DNA theory explains ... these latent viruses is the Epstein Barr Virus (EBV), and ... (RA) is a chronic inflammatory disease that destroys the body’s ... RA patients have high concentrations of EBV DNA in their ...
Breaking Biology Technology:Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2Biohack Pure Offers 5 Tips for Increasing Memory in 2014 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3
Cached News: