UV Skin Damage In A Different Light

Despite all the warnings to avoid exposure to the sun and to wear sunscreen, scientists don't really know how the sun damages our skin. Now, they're a bit closer to the answer.

Two scientists recently discovered that sunlight triggers a harmful reaction when it strikes a molecule in our skin--ironically a molecule once thought to be "nature's sunscreen." The work suggests the science behind the sagging, leathery skin typical of long-term sun worshipers, and may also shed light on how ultraviolet light causes skin cancer.

"We studied a natural component of human skin exposed to ultraviolet light and uncovered a new chemical reaction that may contribute to aging [of the skin] and cancer," said Dr. John Simon, who led the study.

The research will appear in the September 1 issue of the Proceedings of the National Academy of Sciences. The work was conducted at the University of California, San Diego by Dr. John D. Simon (who is now at Duke University), and his graduate student Kerry Hanson (who is now a postdoctoral fellow at the University of Illinois at Urbana-Champaign).

The sun's harmful rays come in two flavors: ultraviolet A and ultraviolet B. Evidence mounts that ultraviolet A and B both play a role in causing skin cancer and photoaging, which is characterized by deep, premature wrinkles, thickened skin, and age spots.

Time, gravity, and heredity notwithstanding, "something like 90 percent of all the visible signs of aging are from ultra-violet sources," said Dr. Kerry Hanson. "Photoaging is not just a cosmetic effect. It destroys the integrity of your skin."

The focus of this study is the sun-sensitive molecule called trans-urocanic acid (t-UA). Formed in the top layer of the skin, t-UA molecules cover our bodies, acting like antennae for light. In the 1950s, urocanic acid was hailed as a "natural sunscreen" because it absorbs ultraviolet B light. It was thus thought to protect against damage by such rays, which can potentially

Contact: Alisa Machalek
(301) 496-7301
NIH/National Institute of General Medical Sciences

Page: 1 2 3

Related biology news :

1. Damaged genes in aging human brain provide clues to cognitive decline
2. Damage from acid rain pollution is far worse than previously believed
3. Damaged DNA synthesis enzyme shown to cause progressive muscle weakening
4. Damaged spinal cord found to have greater potential for nerve regrowth than thought possible
5. Concern Unfounded About Damage From Vitamin C
6. Enzyme Required To Prolong Life In Worms Identified By Researchers At Columbia; Key Enzyme Appears To Protect Animal Cells From Oxidative Damage
7. UCSF Scientists Report On A Transcription Factor That Could Stimulate Heart Cells To Repair Damage Caused By Heart Attacks Or Birth Defects
8. Jefferson Scientists Find Further Proof Of Damage To The FHIT Gene In Breast Cancers
9. Study Indicates Adolescent Smokers Are More Susceptible To Long-Term DNA Damage From Smoking Than Adults Smokers
10. Spider Venom Stops Stroke Brain Damage
11. Common Respiratory Virus Identified As One Cause Of Heart Muscle Damage That Can Lead To Sudden Death

Post Your Comments:

(Date:5/12/2016)... , May 12, 2016 WearablesResearch.com , ... published the overview results from the Q1 wave of ... recent wave was consumers, receptivity to a program where ... with a health insurance company. "We were ... share," says Michael LaColla , CEO of Troubadour ...
(Date:4/26/2016)... LONDON , April 26, 2016 /PRNewswire/ ... Systems, a product subsidiary of Infosys (NYSE: ... partnership to integrate the Onegini mobile security platform ... http://photos.prnewswire.com/prnh/20151104/283829LOGO ) The integration ... security to access and transact across channels. Using ...
(Date:4/14/2016)... Israel , April 14, 2016 ... Authentication and Malware Detection, today announced the appointment of ... assumed the new role. Goldwerger,s leadership appointment ... on the heels of the deployment of its platform ... BioCatch,s behavioral biometric technology, which discerns unique cognitive and ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 2016 Houston Methodist Willowbrook Hospital has ... Association to serve as their official health care ... Willowbrook will provide sponsorship support, athletic training services, ... coaches, volunteers, athletes and families. "We ... Association and to bring Houston Methodist quality services ...
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge ... envision new ways to harness living systems and biotechnology, ... Art (MoMA) in New York City ... 130 participating students, showcased projects at MoMA,s Celeste Bartos ... Paola Antonelli , MoMA,s senior curator of architecture and ...
(Date:6/23/2016)... , ... June 23, 2016 , ... STACS DNA Inc., ... Leader at the Arkansas State Crime Laboratory, has joined STACS DNA as a Field ... DNA team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In further expanding ...
(Date:6/23/2016)... 23, 2016  Blueprint Bio, a company dedicated to ... medical community, has closed its Series A funding round, ... "We have received a commitment from Forentis ... need to meet our current goals," stated Matthew ... runway to complete validation on the current projects in ...
Breaking Biology Technology:
Cached News: