HOME >> BIOLOGY >> NEWS
Undergrad probes regeneration of nerve cell branches

Paul Han, a Johns Hopkins University junior from Riverside, Calif., has conducted original research that adds to scientists understanding of the special circumstances under which nerve cells in the central nervous system may be able to regrow damaged branches.

Han, who is majoring in neuroscience, was among 42 Johns Hopkins students to receive a Provost's Undergraduate Research Award to finance his research in the 2001-2002 academic year. He presented results from his research at a campus awards ceremony March 7.

Researchers had thought for many years that mature nerve cells either wholly or partially located in the brain or the spinal cord could not regenerate after damage to their branches, which are known scientifically as axons. They had identified a family of proteins known as myelin-associated proteins, prevalent in the brain and spine, and shown in the laboratory that these proteins blocked growth of new axons in mature nerve cells.

However, those same inhibitory compounds cannot block the growth of new axons on immature nerve cells. And scientists have found a couple of circumstances that seem to push mature nerve cells towards states where their regenerative ability returns.

For example, Hans mentor Paul Hoffman, an associate professor of ophthalmology, showed that a slightly altered version of a naturally occurring compound could restore regenerative ability in the laboratory to axons of mature nerve cells that entered the central nervous system. That altered form of the naturally occurring compound is known as db cAMP.

While many researchers in the field emphasize the inhibitors in the central nervous system and other environmental factors as the main roadblocks to regeneration, Hoffman and Han suspect intrinsic differences between mature and immature nerve cells may be key contributors. Han used his Provosts Award to further probe how closely mature neurons that had been newly enabled to regenerate axons in the
'"/>

Contact: Michael Purdy
mcp@jhu.edu
410-516-7160
Johns Hopkins University
16-Mar-2002


Page: 1 2

Related biology news :

1. Undergraduate research experience advances education
2. Undergraduate students physics research earns trip to international conference
3. Merck/AAAS announce 2003 winners for outstanding Undergraduate Research Programs
4. Merck/AAAS announce 2002 winners for Undergraduate Science Research Program
5. Undergraduate unraveling genetic mysteries in fruit flies
6. Undergrads digital model of amoeba helps scientists study human cells
7. Merck/AAAS Undergraduate Science Research Program expands to become national
8. Nobel Laureate David Baltimore To Speak To NYU Undergrads
9. UD Education News: HHMI Award Supports Undergraduate Discovery
10. Hopkins Engineering Undergrads Inventions: Power Tools For Double Amputee, Military Surveillance Robot
11. Microarrays, key genome expression trackers, work better when probes are sequence-verified

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/23/2018)... , ... August 22, 2018 , ... Lajollacooks4u is proud to have hosted a variety ... third time. Companies, such as Illumina, Qualcomm, Hewlett Packard, Sequenom and more, have all ... their teams. , Part of the reason clientele return is due to Lajollacooks4u’s ...
(Date:8/17/2018)... ... August 16, 2018 , ... With increasing safety requirements, and time and ... are presenting multiple challenges. To be successful in such a competitive environment, it is ... of the multiple tasks needed to develop a new drug or to execute fundamental ...
(Date:8/14/2018)... ... August 13, 2018 , ... Career ... explore opportunities with multiple health systems at once. However, healthcare professionals often have ... another, more efficient option for healthcare providers who wish to explore opportunities and ...
Breaking Biology News(10 mins):
(Date:9/12/2018)... ... 2018 , ... Leading regenerative veterinary medicine company, VetStem Biopharma, ... later this month. The company’s CEO and founder, Dr. Robert Harman, ... chronic kidney disease in felines at a poster session on Saturday, September 29th. ...
(Date:9/12/2018)... ... September 12, 2018 , ... NDA ... professional and former Senior Director of Regulatory Affairs and Quality Systems at WellDoc, ... Director of Regulatory Affairs and Quality Systems at WellDoc, Inc., she conducted quality ...
(Date:9/7/2018)... (PRWEB) , ... September 06, 2018 , ... ... runs from September 25th-28th is a meeting of “The industry’s preeminent event on ... provide drug discovery scientists powerful tools to study these emerging targets in a ...
(Date:9/7/2018)... ... September 06, 2018 , ... Flagship Biosciences’ MuscleMap ... validated to be as effective as manual pathology. The study, “Validation of a ... Biopsies,” was published in the Archives of Pathology & Laboratory Medicine on August ...
Breaking Biology Technology:
Cached News: