HOME >> BIOLOGY >> NEWS
Undergrad probes regeneration of nerve cell branches

Paul Han, a Johns Hopkins University junior from Riverside, Calif., has conducted original research that adds to scientists understanding of the special circumstances under which nerve cells in the central nervous system may be able to regrow damaged branches.

Han, who is majoring in neuroscience, was among 42 Johns Hopkins students to receive a Provost's Undergraduate Research Award to finance his research in the 2001-2002 academic year. He presented results from his research at a campus awards ceremony March 7.

Researchers had thought for many years that mature nerve cells either wholly or partially located in the brain or the spinal cord could not regenerate after damage to their branches, which are known scientifically as axons. They had identified a family of proteins known as myelin-associated proteins, prevalent in the brain and spine, and shown in the laboratory that these proteins blocked growth of new axons in mature nerve cells.

However, those same inhibitory compounds cannot block the growth of new axons on immature nerve cells. And scientists have found a couple of circumstances that seem to push mature nerve cells towards states where their regenerative ability returns.

For example, Hans mentor Paul Hoffman, an associate professor of ophthalmology, showed that a slightly altered version of a naturally occurring compound could restore regenerative ability in the laboratory to axons of mature nerve cells that entered the central nervous system. That altered form of the naturally occurring compound is known as db cAMP.

While many researchers in the field emphasize the inhibitors in the central nervous system and other environmental factors as the main roadblocks to regeneration, Hoffman and Han suspect intrinsic differences between mature and immature nerve cells may be key contributors. Han used his Provosts Award to further probe how closely mature neurons that had been newly enabled to regenerate axons in the
'"/>

Contact: Michael Purdy
mcp@jhu.edu
410-516-7160
Johns Hopkins University
16-Mar-2002


Page: 1 2

Related biology news :

1. Undergraduate research experience advances education
2. Undergraduate students physics research earns trip to international conference
3. Merck/AAAS announce 2003 winners for outstanding Undergraduate Research Programs
4. Merck/AAAS announce 2002 winners for Undergraduate Science Research Program
5. Undergraduate unraveling genetic mysteries in fruit flies
6. Undergrads digital model of amoeba helps scientists study human cells
7. Merck/AAAS Undergraduate Science Research Program expands to become national
8. Nobel Laureate David Baltimore To Speak To NYU Undergrads
9. UD Education News: HHMI Award Supports Undergraduate Discovery
10. Hopkins Engineering Undergrads Inventions: Power Tools For Double Amputee, Military Surveillance Robot
11. Microarrays, key genome expression trackers, work better when probes are sequence-verified

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Undergrad probes regeneration nerve cell branches

(Date:4/15/2014)... Biologists at UC San Diego have succeeded in ... hormone responsible for growth and resistance to drought. ... studies to determine how the hormone helps plants ... by the continuing increase in the atmosphere,s carbon ... achievement appears in the April 15 issue of ...
(Date:4/15/2014)... Looking at the question of how social behavior has ... universities in Mainz and Basel have gained new insights ... simply compete for food. Rather the siblings share what ... absent," explained Dr. Jol Meunier of the Evolutionary Biology ... University of Mainz (JGU). The team of biologists from ...
(Date:4/15/2014)... (April 15, 2014) The American Association of Anatomists ... All awards will be presented during the Closing ... Hotel on Tuesday, April 29th at 7:30 p.m. during ... , The 2014 award winners are: , ... PhD, of the Icahn School of Medicine at Mount ...
Breaking Biology News(10 mins):Biologists develop nanosensors to visualize movements and distribution of plant hormone 2Sibling cooperation in earwig families gives clues to early evolution of social behavior 2American Association of Anatomists 2014 award winners 2
(Date:1/15/2014)... January 15, 2014 This webinar ... on nonclinical and clinical safety assessment in biosimilars. ... guide a path for biosimilar drug development, however ... of biosimilarity with regards to quality, safety and ... of biosimilar drug development and registration, development strategies ...
(Date:1/15/2014)... NC (PRWEB) January 15, 2014 ... an enhancement to its Online Web Portal for Life ... now have the ability to specify the subject matter ... nearly 50 life science sub-domains. This will help reduce ... and scientific fields, and decrease the likelihood of error. ...
(Date:1/14/2014)... Doylestown, PA (PRWEB) January 14, 2014 ... – 11 p.m. , Location: Warrington Country Club, 1360 ... Hepatitis B Foundation, the only national nonprofit organization solely ... improving the quality of life for those affected worldwide, ... 11 at Warrington Country Club in Warrington, Pa. ...
(Date:1/14/2014)... York, NY (PRWEB) January 14, 2014 ... initiated coverage of Alliqua, Inc. (OTCQB: ALQA). Alliqua ... and marketing proprietary products to serve the wound ... , In late 2012, Alliqua was restructured ... launched the company’s new strategy to become a ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2DTS Improves Efficiency for Life Science Document Translations 2Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
Cached News: