HOME >> BIOLOGY >> NEWS
Undergrad probes regeneration of nerve cell branches

Paul Han, a Johns Hopkins University junior from Riverside, Calif., has conducted original research that adds to scientists understanding of the special circumstances under which nerve cells in the central nervous system may be able to regrow damaged branches.

Han, who is majoring in neuroscience, was among 42 Johns Hopkins students to receive a Provost's Undergraduate Research Award to finance his research in the 2001-2002 academic year. He presented results from his research at a campus awards ceremony March 7.

Researchers had thought for many years that mature nerve cells either wholly or partially located in the brain or the spinal cord could not regenerate after damage to their branches, which are known scientifically as axons. They had identified a family of proteins known as myelin-associated proteins, prevalent in the brain and spine, and shown in the laboratory that these proteins blocked growth of new axons in mature nerve cells.

However, those same inhibitory compounds cannot block the growth of new axons on immature nerve cells. And scientists have found a couple of circumstances that seem to push mature nerve cells towards states where their regenerative ability returns.

For example, Hans mentor Paul Hoffman, an associate professor of ophthalmology, showed that a slightly altered version of a naturally occurring compound could restore regenerative ability in the laboratory to axons of mature nerve cells that entered the central nervous system. That altered form of the naturally occurring compound is known as db cAMP.

While many researchers in the field emphasize the inhibitors in the central nervous system and other environmental factors as the main roadblocks to regeneration, Hoffman and Han suspect intrinsic differences between mature and immature nerve cells may be key contributors. Han used his Provosts Award to further probe how closely mature neurons that had been newly enabled to regenerate axons in the
'"/>

Contact: Michael Purdy
mcp@jhu.edu
410-516-7160
Johns Hopkins University
16-Mar-2002


Page: 1 2

Related biology news :

1. Undergraduate research experience advances education
2. Undergraduate students physics research earns trip to international conference
3. Merck/AAAS announce 2003 winners for outstanding Undergraduate Research Programs
4. Merck/AAAS announce 2002 winners for Undergraduate Science Research Program
5. Undergraduate unraveling genetic mysteries in fruit flies
6. Undergrads digital model of amoeba helps scientists study human cells
7. Merck/AAAS Undergraduate Science Research Program expands to become national
8. Nobel Laureate David Baltimore To Speak To NYU Undergrads
9. UD Education News: HHMI Award Supports Undergraduate Discovery
10. Hopkins Engineering Undergrads Inventions: Power Tools For Double Amputee, Military Surveillance Robot
11. Microarrays, key genome expression trackers, work better when probes are sequence-verified

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Undergrad probes regeneration nerve cell branches

(Date:11/18/2014)... 17, 2014   News Highlights: ... to develop The Partners Data Lake, an agile ... Data Lake will allow researcher and clinicians to ... and the lives of patients , The ... activities across the Partners system, breaking down physical ...
(Date:11/15/2014)... YORK , Nov. 13, 2014  While we may ... technology Doctor McCoy used in "Star Trek" to gain instant ... tools designed to work with smartphones and tablets for monitoring ... of the healthcare world. This may seem a tad Orwellian ... ready to adopt some of these technological opportunities into their ...
(Date:11/10/2014)... appearing on U.S. store shelves in early 2010, and ... The small packets can be tossed into a washing ... or powder. The convenience, though, has come with risks ... at Nationwide Children,s Hospital found that from 2012 through ... children younger than 6 years of age swallowing, inhaling, ...
Breaking Biology News(10 mins):Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 2Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 3Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 4Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 5Americans May Be Ready for a Brave New World of Healthcare 2Americans May Be Ready for a Brave New World of Healthcare 3Americans May Be Ready for a Brave New World of Healthcare 4Study finds laundry detergent pods, serious poisoning risk for children 2
(Date:11/26/2014)... 2014 The Alliance for Safe ... of European physicians at the "1 ST ... Therapies" at the Spanish Ministry of Health, Social ... and the Spanish Bioindustry Association (ASEBIO), included regulators ... Spanish oncology and rheumatology societies, representatives from a ...
(Date:11/26/2014)... 26, 2014 PMG Research, Inc. ... Research is a network of sites that provide clinical research ... 2 million patient lives through its partnerships with large physician ... 11 hub site locations in the Southeastern United States and ... of the board will be held by: Dr. ...
(Date:11/26/2014)... CA (PRWEB) November 25, 2014 Silicon ... joins forces with RPM Alliance , provider of ... pharmaceutical companies. With the latest addition to its CRO ... free validated EDC system to India. , “We ... a robust and customizable EDC platform which is both ...
(Date:11/26/2014)... 2014 Global biostimulants market is ... at an estimated CAGR of 12.5%. In order ... products with least ecological impacts, farmers are looking ... boost crop yield more effectively & efficiently. Biostimulants ... improve the return on investments. , Leading companies ...
Breaking Biology Technology:ASBM Presents European Physicians Survey at Spanish Ministry of Health 2PMG Research Names Medical Advisory Board 2PMG Research Names Medical Advisory Board 3RPM Alliance Joins Clinovo’s CRO Partnership Program, Further Strengthening Its Presence in Southern California and India 22019 Biostimulants Market to Grow at a CAGR of 12.5% Says a New Research Report Available at RnRMarketResearch.com 22019 Biostimulants Market to Grow at a CAGR of 12.5% Says a New Research Report Available at RnRMarketResearch.com 32019 Biostimulants Market to Grow at a CAGR of 12.5% Says a New Research Report Available at RnRMarketResearch.com 4
Cached News: