HOME >> BIOLOGY >> NEWS
Understanding our ape 'cousins:' chimpanzee genetics may shed light on human diseases

A French version of this release is available by clicking here.
A German version of this release is available by clicking here.

The human brain shows strikingly different patterns of gene expression compared to the chimpanzee brain, a difference that isn't seen in other parts of the body like the liver and white blood cells, an international research team reports.

Their study in the 12 April issue of the journal Science, published by the American Association for the Advancement of Science, may shed light on why chimps and humans are so genetically similar--humans and chimpanzees share 98.7 percent of their DNA sequences--yet so mentally and physically different.

Zeroing in on these differences could also help scientists learn more about the genetics underlying medical traits such as susceptibility to AIDS, malaria, and Alzheimer's disease, say the Science researchers, led by Svante Pbo of the Max-Planck-Institute of Evolutionary Anthropology in Leipzig, Germany.

The differences between humans and their closest relatives are more a matter of quantity than quality, according to the report. Differences in the amount of gene and protein expression, rather than differences in the structure of the genes or proteins themselves, distinguish the two species. The overall pattern suggests that the human brain may have experienced accelerated evolutionary change.

Pbo and colleagues searched for these differences using gene chips carrying tiny dabs of human DNA, representing about 18,000 genes. The chip DNA interacted with genetic material purified from brain and liver tissue collected from humans, chimpanzees, and macaque monkeys, allowing the researchers to measure levels of gene expression in each of the species.

Gene expression proved
'"/>

Contact: Lisa Onaga
lonaga@aaas.org
202-326-7088
American Association for the Advancement of Science
11-Apr-2002


Page: 1 2 3

Related biology news :

1. Understanding celiac disease
2. Understanding nutrition labels can lead to healthier eating
3. New Understanding Evolution Web site provides one-stop-shop for nations science teachers
4. Understanding urinary tract infections
5. Salk news: Understanding organ placement
6. John Allen Paulos receives prestigious AAAS Award for Public Understanding of S&T
7. Understanding the impact of genetic technology
8. Salk news: Understanding gene function
9. Understanding obesity: New research examines how hunger signals work in the brain
10. From da Vinci to Monet: Understanding how artists can manipulate the human visual system
11. Understanding acetaminophen poisoning

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/24/2017)... Janice Kephart , former 9/11 ... Partners, LLP (IdSP) , today issues the following ... March 6, 2017 Executive Order: Protecting the ... be instilled with greater confidence, enabling the reactivation ... applications are suspended by until at least July ...
(Date:4/18/2017)... , April 18, 2017  Socionext Inc., a global expert ... a media edge server, the M820, which features the company,s hybrid ... software provided by Tera Probe, Inc., will be showcased during the ... the NAB show at the Las Vegas ... ...
(Date:4/13/2017)... 13, 2017 UBM,s Advanced Design and Manufacturing ... feature emerging and evolving technology through its 3D Printing ... run alongside the expo portion of the event and ... demonstrations focused on trending topics within 3D printing and ... manufacturing event will take place June 13-15, 2017 at the ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... 2017 , ... They call it the “hairy ball.” It’s ... of a system of linkages and connections so complex and dense that “it ... science at Worcester Polytechnic Institute (WPI) and director of the university’s bioinformatics and ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... Market with the addition of its newest module, US Hemostats & Sealants. , ... thrombin hemostats, absorbable hemostats, fibrin sealants, synthetic sealants and biologic sealants used in ...
(Date:10/11/2017)... , ... October 11, 2017 , ... ... gene in its endogenous context, enabling overexpression experiments and avoiding the use of ... small RNA guides is transformative for performing systematic gain-of-function studies. , This ...
(Date:10/11/2017)... 2017  VMS BioMarketing, a leading provider of patient support ... Nurse Educator (CNE) network, which will launch this week. The ... health care professionals to enhance the patient care experience by ... other health care professionals to help women who have been ... ...
Breaking Biology Technology:
Cached News: