HOME >> BIOLOGY >> NEWS
Unexpected links found between many RNA viruses

March 25, 2002 -- Howard Hughes Medical Institute researchers have discovered surprising parallels in the way that three different classes of RNA viruses replicate. The discovery suggests that there might one day be a common strategy to kill many different RNA viruses, a group that includes HIV, rotavirus, hepatitis C and polio viruses.

In an article published in the March 2002 issue of the journal Molecular Cell, HHMI investigator Paul Ahlquist and colleagues at the University of Wisconsin at Madison described the parallels among positive-strand RNA viruses ([+]RNA), retroviruses and double-stranded RNA viruses. Since these viruses cause a broad range of diseases, the scientists believe that finding a common link between the viruses may be the first step to devising more general virus control or treatment strategies. Positive-strand RNA viruses are those that first copy their RNA genome into a negative-strand intermediate RNA before replicating their RNA. These viruses cause hepatitis C, encephalitis, hemorrhagic fevers, polio, foot and mouth disease and the common cold, and many other illnesses.

Retroviruses and other reverse-transcribing viruses, which include HIV and hepatitis B, first copy their RNA into DNA before replicating their genome back into RNA. Double-stranded RNA viruses -- which include the rotavirus that kills about one million children a year in developing countries -- separates its strands and copies one to replicate itself.

Ahlquist and his colleagues discovered that, although the viruses seem to take distinct routes to replication, all three types use related pathways and structures to replicate their genes. By linking three of the six major classes of viruses, the results offer a significant unification within the field of virology.

The multiple functional parallels we have found in replication mechanisms reveal unexpe
'"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
25-Mar-2002


Page: 1 2 3

Related biology news :

1. Unexpected changes in Earths climate observed on the dark side of the moon
2. Researchers Find Unexpected Feature In Plankton Nervous System
3. Recovery From Mass Extinction Is Unexpectedly Diverse
4. USC study links historical increases in life span to lower childhood exposure to infection
5. A probable cause for high blood pressure identified - shows links with diabetes
6. Rutgers-Newark biologist links presence of protein to spread of cancerous cells
7. Study links high carbohydrate diet to increased breast cancer risk
8. Italian research links diet with endometriosis risk
9. New 20-year study links COPD and asthma
10. Experiment station researcher looking for missing links in corn
11. Study links diabetes and colorectal cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: