Univ. of Pittsburgh Medical Center leads group buying PPL'S cloning, stem cell business

e-knockout pigs will likely produce up to 40 more double-knockout pigs by the end of this summer.

To operate its xenotransplantation and other businesses, Regenecor Holdings has formed two subsidiaries. Regenecor Inc. of Virginia retains PPL's existing work force and infrastructure in Blacksburg, where all current work will continue, including the expansion of its cloned pig herd for xenotransplantation. Regenecor (PA), Inc. will carry out pivotal animal and clinical studies involving pancreatic islets cells and whole organs.

Such studies will commence after review by appropriate government bodies and will only involve clinical studies in accordance with federal guidelines. Following these and other studies, Regenecor-sponsored human xenotransplant trials could take place at UPMC at some point in the future.

Regenecor Holdings will be governed by a board of directors with Amadeo Marcos, M.D., professor of surgery and clinical director of transplantation at the Thomas E. Starzl Transplantation Institute and the University of Pittsburgh School of Medicine, as its chairman. David Ayares, Ph.D., formerly COO and vice president of research at PPL, has been named CEO of Regenecor Inc. and a member of the board of Regenecor Holdings. Thomas E. Starzl, M.D., Ph.D., professor of surgery at Pitt's School of Medicine, will chair the company's scientific advisory board.

In addition to the 24 employed in Virginia, Regenecor will draw upon the talent and resources of leading scientists at the University of Pittsburgh and other institutions through various collaborations. Over time, new jobs could be generated in both Virginia and Pittsburgh.

To support Regenecor's Pittsburgh-based start-up operations, the Pittsburgh Life Sciences Greenhouse has committed $100,000 for the purpose of rental support and capital equipment expenses. The commitment recognizes Regenecor's potential to stimulate job growth and enhance the region's life sciences an

Contact: Lisa Rossi
University of Pittsburgh Medical Center

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