HOME >> BIOLOGY >> NEWS
University Health Network researchers discover new class of human stem cells

(Toronto, June 9, 2003) Scientists with University Health Network have discovered a new class of human stem cells that rapidly grow when implanted in the bone marrow of mice. The findings, available today in an advance on-line publication of the international scientific journal Nature Medicine, are a major advancement in human stem cell research with possible significant clinical implications for designing more effective cancer therapies.

This is an exciting discovery because for the first time we have found human stem cells that rapidly rebuild a blood system, said Dr. John Dick, lead author of the study, senior scientist with UHN, and a professor in the University of Torontos Department of Molecular and Medical Genetics. The potential is that it may allow transplant patients to quickly regain their blood cells, which are critical to their immune system.

The scientists identified the new stem cells after injecting a batch of stem cells directly into the bone of mice, instead of the traditional method of intravenous injection into the blood stream. They observed this new subpopulation of stem cells rapidly repopulate the blood-producing system of the mice, produced high levels of blood cells within the first week or two after transplant, which is one- to two-weeks earlier than the normal rate. This discovery builds on the Dr. Dicks pioneering method of studying human stem cells by transplanting them into immunodeficient mice which will not reject the human cells.

The discovery could have far reaching implications for cancer and transplant patients whose immune systems are weakened by their treatment. These patients are very vulnerable to infections, usually for as long as three weeks after the treatment, until their blood system recovers enough to fight off infections.

If these new human stem cells rebuild the blood system of a person as they have in the mice in this study, it may significantly reduce the time a patient is at risk,
'"/>

Contact: Vince Rice
vince.rice@uhn.on.ca
416-946-4501
University of Toronto
8-Jun-2003


Page: 1 2

Related biology news :

1. Indiana University, EPA to study airborne PCBs
2. University of Alberta researcher looks for clues to mysterious disease
3. Northeastern University receives $12.4 million NSF grant for creation of nanomanufacturing institute
4. Washington University in St. Louis leads group studying aging process
5. Tufts University establishes $4 million dollar tissue engineering resource center
6. Case for IBD combination therapy comes from research at Baylor, MIT and Hebrew University
7. As informatics grows, Indiana University helps set research agenda
8. University of Arizona licenses patent for natural fungicide
9. Washington University in St. Louis plays key role in sequencing moss genome
10. University of Pittsburgh receives $10 million grant for head and neck cancer
11. Clemson University spin-off uses corn to make plastics, provide cleaner air

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/13/2018)... ... November 13, 2018 , ... ... systems for controlled-environment cultivation applications. VYPR 2 is well suited for sole-source and ... and ornamental growing markets. , “As an all-purpose light which can be ...
(Date:11/13/2018)... ... November 12, 2018 , ... ... events and webinars, will be hosting its 9th Annual Clinical Diagnostics & ... and treatments available, and updates in regulatory processes to ensure patient safety and ...
(Date:11/13/2018)... ... 13, 2018 , ... Kenall has enhanced the popular MedMaster MAEC Series LED ... linear overbed luminaires are equipped with symmetric ambient and asymmetric exam modes, and an ... Intended to be specified in pairs, the MAEC is 8” x 48” and has ...
Breaking Biology News(10 mins):
(Date:11/7/2018)... ... , ... Since September of this year, stem cell biotechnology ... tissue stem cell counting problem in stem cell medicine and the stem cell ... with new educational publications and presentations at clinical trial supply conferences, at meetings ...
(Date:11/5/2018)... , ... November 05, 2018 , ... ... telemedicine company backed by Siemens Healthineers and several healthcare VC firms announces at ... solution and making a history by purchasing tokens and obtaining its first radiology ...
(Date:11/3/2018)... ... November 01, 2018 , ... Triangle Insights Group, a ... as one of the fastest-growing private companies in the United States, appearing on this ... ranks private companies based on percentage revenue growth over the previous three years. ...
(Date:10/31/2018)... ... October 30, 2018 , ... The assessment of cell health ... of experimental biology. Reproducibility of cell-based assays is one of the key points ... assay type, there are many more factors to be considered to decrease data ...
Breaking Biology Technology:
Cached News: