HOME >> BIOLOGY >> NEWS
University Of Kentucky Researcher Awarded MERIT Extension For Study Of Third World Killer

LEXINGTON, KY (Sept. 21, 1998) - Salvatore Turco, Ph.D., professor of biochemistry, University of Kentucky College of Medicine, has received a five-year extension on a National Institutes of Health (NIH) Method to Extend Research in Time (MERIT) award. The National Institute of Allergy and Infectious Diseases at the NIH has awarded Turco $1,583,700 to continue his study, "Glycoconjugates of Leishmania."

Leishmania donovani, a one-cell parasite, is one of the world's major pathogens. It afflicts 10 to 20 million people in Mediterranean and Third World countries. The parasite is transmitted by sand flies and results in the disease called leishmaniasis. Leishmaniasis, which often results in death, is a problem for residents, travelers, and U.S. soldiers stationed in the Middle East. It was a particular issue during Desert Storm, Turco said. Symptoms include sores, high fever and severe disfigurement. There are only antiquated drugs used for cures and preventive measures, despite scientists' understanding of the biology of the parasite's attack on the human body.

"We are trying to determine how the parasite survives in the human host," Turco said. "We suspect there is something unusual about the Leishmania cell surface that we feel is responsible for the parasite to invade the body and survive with impunity."

Leishmania's cell surface contains a complex molecule made up of sugar, fat and phosphate, called a lipophosphoglycan, that is used for defensive purposes. The molecule prevents the host animal's white cells, called macrophages, from being activated and attacking the parasite. Without the lipophosphoglycan, the parasite is destroyed by macrophages.

Researchers hope that the molecule might play a key role in creating treatments or preventive therapies for leishmaniasis.


'"/>

Contact: Kim Cumbie
krcumb0@pop.uky.edu
(606) 323-6363
University of Kentucky Medical Center
22-Sep-1998


Page: 1

Related biology news :

1. Indiana University, EPA to study airborne PCBs
2. University of Alberta researcher looks for clues to mysterious disease
3. Northeastern University receives $12.4 million NSF grant for creation of nanomanufacturing institute
4. Washington University in St. Louis leads group studying aging process
5. Tufts University establishes $4 million dollar tissue engineering resource center
6. Case for IBD combination therapy comes from research at Baylor, MIT and Hebrew University
7. As informatics grows, Indiana University helps set research agenda
8. University of Arizona licenses patent for natural fungicide
9. Washington University in St. Louis plays key role in sequencing moss genome
10. University of Pittsburgh receives $10 million grant for head and neck cancer
11. Clemson University spin-off uses corn to make plastics, provide cleaner air

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/24/2017)... 2017 Janice Kephart , former ... Strategy Partners, LLP (IdSP) , today issues the ... Trump,s March 6, 2017 Executive Order: Protecting ... can be instilled with greater confidence, enabling the ... refugee applications are suspended by until at least ...
(Date:4/13/2017)... According to a new market research report "Consumer ... Administration, and Authorization), Service, Authentication Type, Deployment Mode, Vertical, and Region - ... to grow from USD 14.30 Billion in 2017 to USD 31.75 Billion ... ... MarketsandMarkets Logo ...
(Date:4/6/2017)... LONDON , April 6, 2017 ... Control, RFID, ANPR, Document Readers, by End-Use (Transportation & ... Energy Facility, Oil, Gas & Fossil Generation Facility, Nuclear ... Healthcare, Educational, Other) Are you looking for ... Authentication sector? ...
Breaking Biology News(10 mins):
(Date:6/27/2017)... (PRWEB) , ... June 27, 2017 , ... ... Certification Program (ESTCP), powder activated carbon (PAC)-based materials do not have negative short- ... community at a site contaminated with polychlorinated biphenyls (PCBs) located at the Puget ...
(Date:6/26/2017)... Milwaukee, WI (PRWEB) , ... June 26, 2017 , ... ... today in role of Sales Director, focused on leading new business development and ensuring ... 10 years of experience in the food ingredient industry in technical, marketing and sales ...
(Date:6/23/2017)... ... June 23, 2017 , ... RURO, Inc., a ... of LimitLIS®, its rapidly growing Laboratory Information System. , LimitLIS® version 3 is ... integrity, and provide more customization options. Each of these has been “under the ...
(Date:6/22/2017)... ... June 21, 2017 , ... ... top executive talent in the life sciences industry, today announces a strategic partnership ... The partnership takes full advantage of Beaker’s expertise in executive recruitment solutions, providing ...
Breaking Biology Technology:
Cached News: