HOME >> BIOLOGY >> NEWS
University Of Kentucky Researcher Awarded MERIT Extension For Study Of Third World Killer

LEXINGTON, KY (Sept. 21, 1998) - Salvatore Turco, Ph.D., professor of biochemistry, University of Kentucky College of Medicine, has received a five-year extension on a National Institutes of Health (NIH) Method to Extend Research in Time (MERIT) award. The National Institute of Allergy and Infectious Diseases at the NIH has awarded Turco $1,583,700 to continue his study, "Glycoconjugates of Leishmania."

Leishmania donovani, a one-cell parasite, is one of the world's major pathogens. It afflicts 10 to 20 million people in Mediterranean and Third World countries. The parasite is transmitted by sand flies and results in the disease called leishmaniasis. Leishmaniasis, which often results in death, is a problem for residents, travelers, and U.S. soldiers stationed in the Middle East. It was a particular issue during Desert Storm, Turco said. Symptoms include sores, high fever and severe disfigurement. There are only antiquated drugs used for cures and preventive measures, despite scientists' understanding of the biology of the parasite's attack on the human body.

"We are trying to determine how the parasite survives in the human host," Turco said. "We suspect there is something unusual about the Leishmania cell surface that we feel is responsible for the parasite to invade the body and survive with impunity."

Leishmania's cell surface contains a complex molecule made up of sugar, fat and phosphate, called a lipophosphoglycan, that is used for defensive purposes. The molecule prevents the host animal's white cells, called macrophages, from being activated and attacking the parasite. Without the lipophosphoglycan, the parasite is destroyed by macrophages.

Researchers hope that the molecule might play a key role in creating treatments or preventive therapies for leishmaniasis.


'"/>

Contact: Kim Cumbie
krcumb0@pop.uky.edu
(606) 323-6363
University of Kentucky Medical Center
22-Sep-1998


Page: 1

Related biology news :

1. Indiana University, EPA to study airborne PCBs
2. University of Alberta researcher looks for clues to mysterious disease
3. Northeastern University receives $12.4 million NSF grant for creation of nanomanufacturing institute
4. Washington University in St. Louis leads group studying aging process
5. Tufts University establishes $4 million dollar tissue engineering resource center
6. Case for IBD combination therapy comes from research at Baylor, MIT and Hebrew University
7. As informatics grows, Indiana University helps set research agenda
8. University of Arizona licenses patent for natural fungicide
9. Washington University in St. Louis plays key role in sequencing moss genome
10. University of Pittsburgh receives $10 million grant for head and neck cancer
11. Clemson University spin-off uses corn to make plastics, provide cleaner air

Post Your Comments:
(Date:4/17/2014)... State University engineer has developed a patented technique ... explosive devices. The same technique could help police ... M. and Kay L. Theede chair in engineering ... and his research team have created a template-based ... car trunks. The distance detection method called ...
(Date:4/17/2014)... in Europe, Asia and the United States are spreading ... impacting native honeybee populations at this time, according to ... including Nosema microsporidia and Varroa ... to these invasive pests, which suggests to us that ... and the United States currently are not necessary in ...
(Date:4/17/2014)... reporting in the Cell Press journal Current Biology ... with rather novel sex lives. The Brazilian insects, which ... Neotrogla , are the first example of an ... has been identified in several different animals, Neotrogla ... organ is also reversed," says Kazunori Yoshizawa from Hokkaido ...
Breaking Biology News(10 mins):Patented research remotely detects nitrogen-rich explosives 2East African honeybees are safe from invasive pests… for now 2East African honeybees are safe from invasive pests… for now 3In sex-reversed cave insects, females have the penises 2
(Date:1/15/2014)... (PRWEB) January 15, 2014 This webinar ... nonclinical and clinical safety assessment in biosimilars. , Regulatory ... for biosimilar drug development, however the complex nature of ... quality, safety and efficacy extremely challenging. Based on the ...
(Date:1/15/2014)... DTS Language Services, Inc . is pleased ... Life Science organizations who need document translations. Clients will ... their documents in advance with a selection of nearly 50 ... often a critical factor in clinical and scientific fields, and ...
(Date:1/14/2014)... January 14, 2014 Date: Friday, April 11, ... Warrington Country Club, 1360 Almshouse Road, Warrington, Pa. ... organization solely dedicated to finding a cure for hepatitis B ... will host its annual Crystal Ball on Friday, April 11 ...
(Date:1/14/2014)... New York, NY (PRWEB) January 14, 2014 ... coverage of Alliqua, Inc. (OTCQB: ALQA). Alliqua is an ... products to serve the wound care market. , Free ... Alliqua was restructured with a seasoned management team and ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2DTS Improves Efficiency for Life Science Document Translations 2Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
Cached News: