HOME >> BIOLOGY >> NEWS
University of Kentucky Neuroscientist Develops Unique Device For Treatment Of Brain Tumors

LEXINGTON, Ky., Aug. 3, 1998 -- A device patented by a University of Kentucky Chandler Medical Center neuroscientist has shown promising early results in patient survival times in treatment of malignant gliomas, the most common type of brain tumor in adults.

The device, called Serodur, delivers chemotherapy to a non-operable brain tumor through a small plastic tube that runs directly into the center of the tumor. The tube is connected to a small plastic bubble, called an Ommaya reservoir, that is implanted under the patient's scalp. A cellophane-like permeable membrane in the bubble regulates the flow of the cancer-fighting drug into the tumor.

"By using Serodur, we're able to give small total doses that produce large concentrations of anticancer drugs in the brain without exposing the patient's body to the systemic effects of the medicine," said Roy Patchell, M.D., University of Kentucky Chandler Medical Center neuroscientist and inventor of the device. "Our studies are preliminary, but we've seen some long-term survivors, which is unusual for this kind of cancer."

More than half of the patients who contract a malignant glioma live less than one year, despite aggressive treatment with surgery, radiation therapy and intravenous chemotherapy, Patchell said. Intravenous chemotherapy often causes severe toxicity, so patients cannot be given enough of the drug to have effective results. In addition, many anticancer drugs cannot cross the blood-brain barrier in concentrations high enough to kill the tumor. When drugs do get into the brain, they only remain active for a few hours -- not enough time to destroy the tumor.

By running the tube directly into patients' tumors, Patchell has been able to eliminate side effects normally associated with chemotherapy, such as nausea, hair loss and fatigue. The survival rates of patients who have tried Serodur is even more impressive.

"Most patients with recurr
'"/>

Contact: Kim Cumbie
krcumb0@pop.uky.edu
(606) 323-6363
University of Kentucky Medical Center
3-Aug-1998


Page: 1 2

Related biology news :

1. Indiana University, EPA to study airborne PCBs
2. University of Alberta researcher looks for clues to mysterious disease
3. Northeastern University receives $12.4 million NSF grant for creation of nanomanufacturing institute
4. Washington University in St. Louis leads group studying aging process
5. Tufts University establishes $4 million dollar tissue engineering resource center
6. Case for IBD combination therapy comes from research at Baylor, MIT and Hebrew University
7. As informatics grows, Indiana University helps set research agenda
8. University of Arizona licenses patent for natural fungicide
9. Washington University in St. Louis plays key role in sequencing moss genome
10. University of Pittsburgh receives $10 million grant for head and neck cancer
11. Clemson University spin-off uses corn to make plastics, provide cleaner air

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... NXT-ID, Inc. (NASDAQ:   NXTD ) ("NXT-ID" or ... independent Directors Mr. Robin D. Richards and Mr. ... the company,s corporate governance and expertise. ... Gino Pereira , Chief Executive Officer said," ... and benefiting from their considerable expertise as we move forward ...
(Date:4/5/2017)... 2017  The Allen Institute for Cell Science today ... one-of-a-kind portal and dynamic digital window into the human ... first application of deep learning to create predictive models ... and a growing suite of powerful tools. The Allen ... future publicly available resources created and shared by the ...
(Date:4/5/2017)... -- KEY FINDINGS The global market for ... of 25.76% during the forecast period of 2017-2025. The ... the growth of the stem cell market. ... INSIGHTS The global stem cell market is segmented on ... stem cell market of the product is segmented into ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... , ... October 11, 2017 , ... ComplianceOnline’s Medical Device ... on 7th and 8th June 2018 in San Francisco, CA. The Summit brings together ... as several distinguished CEOs, board directors and government officials from around the world to ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... implantation and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... and maternal age to IVF success. , After comparing the results from the ...
(Date:10/10/2017)... ... October 10, 2017 , ... Dr. Bob Harman, founder and CEO ... Diego Rotary Club. The event entitled “Stem Cells and Their Regenerative ... attendees. Dr. Harman, DVM, MPVM was joined by two human doctors: Peter B. ...
(Date:10/9/2017)... 9, 2017  BioTech Holdings announced today identification ... its ProCell stem cell therapy prevents limb loss ... Company, demonstrated that treatment with ProCell resulted in ... as compared to standard bone marrow stem cell ... in reduction of therapeutic effect.  ...
Breaking Biology Technology:
Cached News: