HOME >> BIOLOGY >> NEWS
University of Pittsburgh researchers demonstrate metabolic link between large,,waists and colorectal cancer

PITTSBURGH, July 15 -- People with large waistlines suffer metabolic changes that significantly predispose them to developing colorectal cancer, according to new data from a University of Pittsburgh-led study whose results are published in the July 7 issue of the Journal of the National Cancer Institute. This information is the first to link intra-abdominal fat, or visceral adipose tissue (VAT), and its associated metabolic changes with colorectal cancer, according to the authors.

"For several years, scientists have recognized that obese people are more likely to develop colorectal cancer. Our study sheds light on the metabolic process underlying this connection," said Robert Schoen, M.D., assistant professor of medicine at the University of Pittsburgh School of Medicine, where he is the medical director of the Center for Families at Risk for Colorectal Cancer. "The metabolic parameters we measured, including glucose, insulin and waist circumference, reveal a risk of colorectal cancer that equals or exceeds other known risk factors, such as having a first-degree relative with this disease or consuming a high-fat or low-fiber diet."

The current report is based on a study of 5,849 people age 65 and older who participated in the Cardiovascular Health Study, a multi-center observational study of risk factors for coronary heart disease and stroke. The researchers found that people with increased waistlines, high levels of glucose (the sugar needed to fuel the body's activities) and high levels of insulin (the hormone that helps dispose of glucose) were twice as likely to develop colorectal cancer as individuals without these characteristics. Individuals in the study who developed colorectal cancer did not differ from their non-affected counterparts in terms of smoking, current aspirin use, alcoholic drinks consumed per week, percent of fat calories in diet or mean number of vegetable or fruit servings per week. Study participant
'"/>

Contact: Lauren Ward
wardle@msx.upmc.edu
412-624-2607
University of Pittsburgh Medical Center
15-Jul-1999


Page: 1 2

Related biology news :

1. Indiana University, EPA to study airborne PCBs
2. University of Alberta researcher looks for clues to mysterious disease
3. Northeastern University receives $12.4 million NSF grant for creation of nanomanufacturing institute
4. Washington University in St. Louis leads group studying aging process
5. Tufts University establishes $4 million dollar tissue engineering resource center
6. Case for IBD combination therapy comes from research at Baylor, MIT and Hebrew University
7. As informatics grows, Indiana University helps set research agenda
8. University of Arizona licenses patent for natural fungicide
9. Washington University in St. Louis plays key role in sequencing moss genome
10. University of Pittsburgh receives $10 million grant for head and neck cancer
11. Clemson University spin-off uses corn to make plastics, provide cleaner air

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... , March 30, 2017  On April 6-7, 2017, ... the Genome hackathon at Microsoft,s headquarters in ... competition will focus on developing health and wellness apps ... Hack the Genome is the first hackathon ... The world,s largest companies in the genomics, tech and ...
(Date:3/28/2017)... 28, 2017 The report "Video ... Monitors, Servers, Storage Devices), Software (Video Analytics, VMS), and ... Global Forecast to 2022", published by MarketsandMarkets, the market ... is projected to reach USD 75.64 Billion by 2022, ... The base year considered for the study is 2016 ...
(Date:3/23/2017)... report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based and Touchless), Product ... by MarketsandMarkets, the market is expected to be worth USD 18.98 billion by ... Continue Reading ... ...      (Logo: http://photos.prnewswire.com/prnh/20160303/792302) ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... BioMedGPS announces expanded coverage of ... newest module, US Hemostats & Sealants. , SmartTRAK’s US Market for Hemostats and ... synthetic sealants and biologic sealants used in surgical applications. BioMedGPS estimates the market ...
(Date:10/11/2017)... , ... October 11, 2017 , ... ... gene in its endogenous context, enabling overexpression experiments and avoiding the use of ... small RNA guides is transformative for performing systematic gain-of-function studies. , This ...
(Date:10/11/2017)... a leading provider of patient support solutions, has announced the ... which will launch this week. The VMS CNEs will address ... enhance the patient care experience by delivering peer-to-peer education programs ... to help women who have been diagnosed and are being ... ...
(Date:10/11/2017)... , ... October 11, 2017 , ... ... (FDA) has granted orphan drug designation to SBT-100, its novel anti-STAT3 (Signal Transducer ... treatment of osteosarcoma. SBT-100 is able to cross the cell membrane and bind ...
Breaking Biology Technology:
Cached News: