HOME >> BIOLOGY >> NEWS
University of Pittsburgh scientist honored for major accomplishment in cancer research

PITTSBURGH, Oct. 26 Yuan Chang, M.D., professor of pathology at the University of Pittsburgh School of Medicine, has been awarded the Paul Marks Prize for Cancer Research by Memorial Sloan-Kettering Cancer Center for her work investigating Kaposi's sarcoma-associated herpesvirus (KSHV), the most recently discovered virus linked to human cancer.

KSHV is the cause of Kaposi's sarcoma, a common cancer among AIDS patients, and also is linked to other immune disorders including a type of B-cell lymphoma and Castleman's disease, a noncancerous but severe disorder characterized by enlargement of the lymph nodes.

Dr. Chang will share the $125,000 Marks Prize with two other scientists under the age of 45 who have made significant contributions to the basic understanding and treatment of cancer.

"Yuan Chang's discovery of KSHV was a seminal breakthrough that has enabled all subsequent understanding of how the virus causes disease, as well as the diagnosis and potential treatment of KSHV infection," said Elliott D. Kieff, M.D., Ph.D., professor of microbiology and molecular genetics at Harvard Medical School. "Her basic and clinical research has transformed our understanding of the most common malignancy in people infected with HIV."

Dr. Chang, 43, co-discovered KSHV, also known as human herpesvirus 8, along with her husband, Patrick Moore, M.D., M.P.H., professor of molecular genetics and biochemistry at the University of Pittsburgh and director of the molecular biology program at the University of Pittsburgh Cancer Institute. Prior to their discovery, Kaposi's sarcoma was believed to be caused by an infectious agent, but the cause of the disease remained unknown.

Since discovering KSHV in 1994, Dr. Chang has continued to study the biology of the virus to understand the basis for its ability to cause cancer. In 1996, she and her colleagues published the DNA sequence of KSHV, revealing that the virus has pirated several cellular
'"/>

Contact: Clare Collins
CollCX@upmc.edu
412-647-3555
University of Pittsburgh Medical Center
26-Oct-2003


Page: 1 2

Related biology news :

1. Indiana University, EPA to study airborne PCBs
2. University of Alberta researcher looks for clues to mysterious disease
3. Northeastern University receives $12.4 million NSF grant for creation of nanomanufacturing institute
4. Washington University in St. Louis leads group studying aging process
5. Tufts University establishes $4 million dollar tissue engineering resource center
6. Case for IBD combination therapy comes from research at Baylor, MIT and Hebrew University
7. As informatics grows, Indiana University helps set research agenda
8. University of Arizona licenses patent for natural fungicide
9. Washington University in St. Louis plays key role in sequencing moss genome
10. University of Pittsburgh receives $10 million grant for head and neck cancer
11. Clemson University spin-off uses corn to make plastics, provide cleaner air

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/26/2020)... ... August 24, 2020 , ... Elgia ... inflammatory and fibrotic diseases, today announced that Dr. Stacie Canan has joined the ... Dr. Canan previously served as Executive Director of Global Health at Bristol Myers ...
(Date:8/23/2020)... (PRWEB) , ... August 21, 2020 , ... ... Rigaku Corporation has been published and is now available on the company’s ... X-ray diffraction—serves the X-ray analysis community, presenting current news and crystallographic research. ...
(Date:8/21/2020)... (PRWEB) , ... August 20, 2020 , ... ... that Hassan Movahhed , a Clinical Operations executive with expertise in clinical ... has joined the firm as an Expert Consultant. Throughout his career, Mr. Movahhed ...
Breaking Biology News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... Slone ... companies, has announced the placement of Julianne Averill , CPA, as Chief ... all financial operations and implementing key business strategies to accelerate Alveo’s growth as ...
(Date:8/15/2020)... ... August 13, 2020 , ... True Terpenes , the leading platform ... Advisory Board (SAB) to research the medical potential of terpenes and the potential ... with terpenes. The board is focused on expanding the recently launched line of effects-based ...
(Date:8/12/2020)... Mass. (PRWEB) , ... August 11, 2020 , ... ... $300,000 a year to expand the Facioscapulohumeral Muscular Dystrophy Clinical Trial Research ... in 2021 and 2022. The network is a consortium of academic research centers ...
(Date:8/12/2020)... Mich. (PRWEB) , ... August 12, 2020 , ... ... Group, Inc. (EMMA International), a global leader in FDA compliance consulting has ... the nation’s fastest-growing private companies. The list represents a unique look at the ...
Breaking Biology Technology:
Cached News: