HOME >> BIOLOGY >> NEWS
Urine Test For Cancer Under Development

Scientists are developing a test that, for the first time, is allowing them to monitor urine for chemical indicators of cancer. It is hoped the test may one day allow early screening, even telling patients what type of cancer they have and its stage of advancement. The researchers say treatment progress might be monitored with the same test.

The highly sensitive technique will be detailed in the April 1 print edition of the peer- reviewed journal Analytical Chemistry, published by the American Chemical Society (ACS), the world's largest scientific society. ACS Web publication of this paper occurred on Feb. 20.

The test looks for derivatives of a class of heterocyclic chemical compounds called pteridines. Pteridine derivatives play important roles in normal cell metabolism, such as mediating the action of crucial enzymes and helping to synthesize some vitamins, according to author Yinfa Ma, Ph.D., of Truman State University in Kirksville, Mo. But Ma, who collaborated on this study with scientists from the Chinese Academy of Sciences, says that malignant tumors appear to "greatly disturb the biosynthesis and metabolism of pteridines." He wanted to see if he could detect, and make sense of, those changes.

Ma analyzed the amounts of eight different pteridine derivatives in cancer patients' urine and found that "each type of tumor shows its own pattern in changes of pteridine concentrations." This suggests it may be possible to diagnose a particular cancer by looking at a person's urine sample.

Although the metabolic importance of pteridines has been known for decades, Ma says their mechanisms are not fully understood because of difficulties in determining their levels. He claims current quantification methods are too time-consuming, not cost effective, and provide poor separation of similarly structured pteridine derivatives. Ma's group tested urine samples by first separating derivatives with high-performance capillary electrophoresis, th
'"/>

Contact: Charmayne Marsh
y_marsh@acs.org
202-872-4445
American Chemical Society
31-Mar-1999


Page: 1 2

Related biology news :

1. Powerful Anti-AIDS Agent Found In Tears And In Urine Of Pregnant Women
2. Urine Tests Will Do Better Than Pelvic Exams To Save Teens From Serious Effects Of Sexually Transmitted Diseases, UCSF Analysis Shows
3. Major New Study Shows HIV-1 Antibodies Found In Urine
4. Results Of Poisoning Visible In Urine
5. Researchers Identify Protein Critical To Urine Concentration
6. Chlamydia Testing Of Urine Samples Can Be Successful
7. Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
8. 16th EORTC NCI AACR Symposium Molecular Targets and Cancer Therapeutics
9. 16th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
10. Cancer gene MYC emerging as key research target
11. Cancer patient, heal thyself

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/12/2019)... ... 12, 2019 , ... FEITIAN Technologies US Inc. , ... announced today the launch of two new payment card types which can both ... cards. These advanced technologies will help all elements of the payment card chain, ...
(Date:3/9/2019)... ... 07, 2019 , ... A firm believer in causes greater than all of ... This donation will help fund not only research to find a cure, but services ... are always on the lookout for ways to make a difference. When The Leukemia ...
(Date:3/9/2019)... ... March 09, 2019 , ... ... & hM4Di ligands – exciting compounds for scientists studying GPCR and DREADD signalling. ... Abuse and the National Institute of Neurological Disorders and Stroke, both institutes of ...
Breaking Biology News(10 mins):
(Date:2/19/2019)... ... February 19, 2019 , ... VetStem Biopharma has long ... In October 2018, VetStem authorized the formation of Personalized Stem Cells, Inc (“PSC”), ... cell patents, data, and FDA filings to launch into human stem cell clinical therapy. ...
(Date:2/14/2019)... ... 14, 2019 , ... Leak Detection Associates (LDA), ... biotechnology and food industries, formally announced today the appointment of two key leadership ... named Chief Executive Officer and will oversee all aspects of the company’s operations, ...
(Date:2/6/2019)... ... February 05, 2019 , ... Firmex ... executive management team to acquire Firmex, one of the fastest-growing and most widely-used ... Montreal-based private equity firm. Debt financing was provided by the Bank of Montreal. ...
(Date:2/2/2019)... ... ... Dust off your Doc Martens, Virun Nutra-BioSciences is fusing punk rock with ... and Tech Festival at the ESports Arena in Santa Ana on Wednesday afternoon, March ... dietary supplement industries, the Nuriv Music and Tech Festival is scheduled one day prior ...
Breaking Biology Technology:
Cached News: