HOME >> BIOLOGY >> NEWS
Use of genetic testing for colorectal cancer may increase screening rates

Boston, MA (October 17, 2002) Individuals with a genetic predisposition for colorectal cancer (CRC) were more likely to be screened for the disease, according to a study presented at the American Association for Cancer Research's (AACR) first annual Frontiers in Cancer Prevention Research meeting. Those carrying the gene alteration were significantly more likely to undergo a colonoscopy (70 percent), compared to those who did not carry the risk-conferring gene alteration (22 percent) and individuals who declined testing (16 percent).

HNPCC is the most common form of inherited colon cancer, and affects at least one person per thousand. People with the HNPCC genetic mutation are encouraged to undergo colonoscopy screening every one to two years.

"Previous studies have indicated that genetic test results have a limited impact on cancer screening behavior," according to Chanita Hughes, Ph.D., assistant professor of psychiatry at the University of Pennsylvania, Philadelphia, and lead investigator of the study. "We were pleased our study found that the results of an HNPCC genetic test may actually motivate colonoscopy screening among those who test positive."

HNPCC is a condition that increases the risk of developing colon cancer and can be detected by genetic testing. Mutations in at least four genes are linked to HNPCC, and an estimated five to 10 percent of all colon cancer cases are believed to result from these mutations. People who carry one or more of the mutations have an 80 to 85 percent risk of developing colorectal cancer by age 75. Colon cancer resulting from HNPCC is diagnosed in people around age 45 (sometimes in people still in their 20s) much earlier than non-inherited forms of colon cancer.

Between 43 to 76 percent of high-risk individuals undergo genetic testing for colorectal cancer. There are three familial factors that determine whether patients should undergo genetic testing for colorectal cancer: three case
'"/>

Contact: Aimee Frank
AMF@spectrumscience.com
202-369-1654
American Association for Cancer Research
17-Oct-2002


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Rare childhood genetic syndrome identified
3. New research shows plants can shuffle and paste gene pieces to generate genetic diversity
4. Scientists decipher genetic code of biothreat pathogen
5. Chemical genetics identifies SARS inhibitors
6. 22nd amino acid synthesized and added to genetic code of e. coli bacteria
7. The impact of genetic variations on the treatment of early rheumatoid arthritis
8. Adaptive changes in the genome may provide insight into the genetics of complex disease
9. New genetic hypothesis for the cause of autism
10. Fossils reveal direct link between global warming and genetic diversity in wildlife
11. A genetic disorder yields insight into genes and cognition

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... , ... September 03, 2020 , ... Brilliant , ... Home System and its products are now available for purchase in the U.S., Canada, ... home, security, AV, and low-voltage products. In addition to being available for purchase through ...
(Date:9/3/2020)... NEW YORK (PRWEB) , ... September 03, 2020 ... ... for real world data, today announced that an extensive third-party assessment of the ... secure and compliant when measured against federal security regulations. The comprehensive evaluation reviewed ...
(Date:8/26/2020)... (PRWEB) , ... August 24, 2020 , ... ... for the treatment of chronic inflammatory and fibrotic diseases, today announced that Dr. ... President of Drug Discovery. , Dr. Canan previously served as Executive Director of ...
Breaking Biology News(10 mins):
(Date:8/3/2020)... ... August 03, 2020 , ... ... Corrigan, President and CEO has been named one of the 100 most inspiring ... sectors, PharmaVoice 100 honorees are selected based on how they have inspired their ...
(Date:7/31/2020)... SHREWSBURY, Mass. (PRWEB) , ... July 29, 2020 ... ... clad wire that can combine up to three different materials for use with ... can combine up to three materials to meet specific design requirements, performance, and ...
(Date:7/22/2020)... ... , ... Join experts from Reed Tech , Gary Saner, Sr. Manager, ... hour live webinar on Thursday, August 13, 2020 at 11am EDT (4pm ... devices. Specifically, for medical devices, the NMPA has departments dealing with medical device registration ...
(Date:7/10/2020)... (PRWEB) , ... July 08, 2020 , ... ... services and products, announces a significant expansion of laboratory operations through its ... for agencies implementing testing programs. , Bode-CARES provides a turnkey ...
Breaking Biology Technology:
Cached News: