HOME >> BIOLOGY >> NEWS
Using lasers, biologists succeed in getting cells to change course

CHAPEL HILL - Most people probably think that most cells in the body -- not counting blood cells -- stay in one place their entire lives just as whole plants do, but nothing could be further from the truth.

These microscopic living structures move a little or a lot, healing wounds, developing embryos, scouting and attacking disease-causing invaders and, sometimes, spreading cancer. As a result, the mechanics and chemistry of how cells get themselves from one place to another fascinates researchers around the world.

Now, using a beam of laser light only a few microns in diameter, University of North Carolina at Chapel Hill scientists have succeeded for the first time in getting such light to alter the course of a moving cell. They have accomplished that by having the laser create active proteins from what are called "caged" proteins that they introduced into the cell.

A report on the research appears in the May 28 issue of the Journal of Cell Biology.

The work has begun attracting attention from other scientists internationally.

"We put caging groups on particular amino acids of the protein we were interested in inside single cells and that makes the proteins less active," said Dr. Kenneth A. Jacobson, professor of cell and developmental biology at the UNC School of Medicine. "Then we directed the laser beam into part of the cells to break the bond between the caging group and the amino acid so that the protein became active again. Afterward, depending on where we shined the light, cells turned by as much as 90 degrees."

Their experiments might be likened to putting the breaks on one rear wheel of a car so that the car would tend to pull to one side or another, Jacobson said.

Besides Jacobson, UNC authors are Drs. Partha Roy, a postdoctoral fellow soon to join the research faculty, and Zenon Rajfur, research associate. Drs. Gerard Marriott and Leslie Loew of the universities of Wisconsin and Connecticut, respectively,
'"/>

Contact: David Williamson
David_Williamson@unc.edu
919-962-8596
University of North Carolina at Chapel Hill
21-Jun-2001


Page: 1 2

Related biology news :

1. Using statistics to decipher secrets of natural mutation
2. Using science to restore habitat for declining species
3. Using soils as filters to prevent crypto from moving to the groundwater
4. Using a companion crop to control weeds organically
5. Using plants and microbes to purify polluted industrial wastewater
6. Using GPR to estimate tree root biomass
7. Using computational power tools to bolster systems biology
8. Using RNA interference to tune gene activity in stem cells
9. Using sewage sludge as fertilizer
10. Using the oceans living light shows to fight terrorism or track the planets most massive migration
11. Using genetic research to treat inflammatory diseases Vienna centre of excellence in biomedicine harnesses basic research

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/2/2016)... 2, 2016   The Weather Company , an IBM ... an industry-first capability in which consumers will be able to ... ask questions via voice or text and receive relevant information ... Marketers have long sought an advertising solution that ... be personal, relevant and valuable; and can scale across millions ...
(Date:5/20/2016)... 2016  VoiceIt is excited to announce its ... By working together, VoiceIt and VoicePass will ... VoicePass take slightly different approaches to voice biometrics, ... and usability. ... partnership. "This marketing and technology partnership ...
(Date:5/3/2016)... 2016  Neurotechnology, a provider of high-precision biometric ... Biometric Identification System (ABIS) , a complete system ... ABIS can process multiple complex biometric transactions with ... fingerprint, face or iris biometrics. It leverages the ... MegaMatcher Accelerator , which have been used ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 2016 Houston Methodist Willowbrook Hospital has ... Association to serve as their official health care ... Willowbrook will provide sponsorship support, athletic training services, ... coaches, volunteers, athletes and families. "We ... Association and to bring Houston Methodist quality services ...
(Date:6/23/2016)... --  EpiBiome , a precision microbiome engineering company, today ... from Silicon Valley Bank (SVB). The financing will allow ... drug development efforts, as well as purchase additional lab ... been an incredible strategic partner to us – one ... provide," said Dr. Aeron Tynes Hammack , EpiBiome,s ...
(Date:6/23/2016)... 2016 Apellis Pharmaceuticals, Inc. today announced ... of its complement C3 inhibitor, APL-2. The trials ... dose studies designed to assess the safety, tolerability, ... in healthy adult volunteers. Forty subjects ... single dose (ranging from 45 to 1,440mg) or ...
(Date:6/23/2016)... ... June 23, 2016 , ... ClinCapture, the only free validated ... will showcase its product’s latest features from June 26 to June 30, 2016 ... on Disrupting Clinical Trials in The Cloud during the conference. DIA (Drug ...
Breaking Biology Technology:
Cached News: