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Vaccines against foodborne disease on horizon

the Uniformed Services University of the Health Sciences in Bethesda, Maryland, successfully transferred a modified version of one of the shiga toxin genes into tobacco plants. This plant-derived vaccine was effective in producing antibodies against the toxin when administered to mice.

"Next the immunized mice will be challenged with the toxin or toxin-producing bacteria to determine if the plant vaccine is protective," says Wen. "Once the protective efficacy of these plant-based vaccines is established, the bacterial genes can then be moved into other plants such as bananas or corn for delivery to humans or animals."


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Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
24-May-2004


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