HOME >> BIOLOGY >> NEWS
Vertex Researchers Report Three-Dimensional Atomic Structure Of JNK3 Enzyme; Report In Structure

Vertex researchers have solved the three-dimensional atomic structure of the JNK3 enzyme, a research advance that may pave the way for new drugs to treat epilepsy and stroke. The discovery, which represents the first known structure of JNK3, will be published in the August 15, 1998 issue of the journal Structure.

JNK3 belongs to the MAP Kinase family of enzymes, a group of proteins that help to transmit signals from the surface of cells to the nucleus, allowing cells to respond to their environment. Pharmaceutical industry interest in JNK3 stems from animal studies that implicate JNK3 in neurological diseases such as epilepsy. Genomic research has shown that mice bred to be deficient in JNK3 show reduced susceptibility to seizure and neuronal cell death.

Vertex's has an established track record of applying structural information to genomic discoveries as part of an effort to discover new drugs against innovative targets. Vertex employs an interdisciplinary approach that integrates biophysics, biology and chemistry towards the efficient design and development of novel pharmaceuticals.


'"/>

Contact: Michael Partridge
partridge@vpharm.com
(617) 577-6108
Vertex Pharmaceuticals
14-Aug-1998


Page: 1

Related biology news :

1. Research Findings Suggest Potent, Broad-Spectrum Antiviral Activity For Vertexs Investigational IMPDH Inhibitor VX-497
2. Phase III Results Suggest Potent Antiviral Activity For Vertex And Glaxo Wellcomes Second-Generation HIV Protease Inhibitor Agenerase TM
3. Vertex Pharmaceuticals/Yale Research Team Uses Gene Knockout Mice To Establish Role Of Caspase-9 In Neuronal Cell Death Pathway
4. Vertex Pharmaceuticals Researchers Report Three-Dimensional Structure Of Hepatitis C Helicase Enzyme; Report In Structure
5. Researchers determine genetic cause of Timothy syndrome
6. Researchers find color sensitive atomic switch in bacteria
7. Researchers identify protein promoting vascular tumor growth
8. Researchers devise potent new tools to curb ivory poaching
9. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
10. Researchers ID chlorophyll-regulating gene
11. Researchers develop fast track way to discover how cells are regulated

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2017)... PUNE, India , April 13, 2017 According ... Identity Proofing, Identity Authentication, Identity Analytics, Identity Administration, and Authorization), Service, Authentication ... by MarketsandMarkets™, the IAM Market is expected to grow from USD 14.30 ... Annual Growth Rate (CAGR) of 17.3%. ... ...
(Date:4/11/2017)... 11, 2017 NXT-ID, Inc. (NASDAQ:   ... announces the appointment of independent Directors Mr. Robin D. ... Board of Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , ... forward to their guidance and benefiting from their considerable expertise ...
(Date:4/5/2017)... 4, 2017 KEY FINDINGS The ... at a CAGR of 25.76% during the forecast period ... primary factor for the growth of the stem cell ... MARKET INSIGHTS The global stem cell market ... and geography. The stem cell market of the product ...
Breaking Biology News(10 mins):
(Date:10/9/2017)... San Antonio, Texas (PRWEB) , ... ... ... a new study published on October 5, 2017, in the medical journal, ... demonstrated equivalence with the gold standard, video EEG, in detecting generalized tonic-clonic ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... Hi-C-based genomic technologies, launched its ProxiMeta™ Hi-C metagenome deconvolution product, featuring the ... and accompanying cloud-based bioinformatics software to perform Hi-C metagenome deconvolution using their ...
(Date:10/6/2017)... ... October 06, 2017 , ... The HealthTech Venture Network ... at their fourth annual Conference where founders, investors, innovative practitioners and collaborators are ... pitch competition showcasing early stage digital health and med tech companies. , This ...
(Date:10/5/2017)... YORBA LINDA, CA (PRWEB) , ... October 05, 2017 , ... ... tech innovators, engineers, and scientists from around the world, is giving back to cancer ... shirt sold in October. , Now through October 31, shoppers can use promo ...
Breaking Biology Technology:
Cached News: