HOME >> BIOLOGY >> NEWS
Very Fruitful Collaboration Between French And German Scientists Yields Unusual Insights Into The Structure Of Membrane Proteins

Scientists from the Max Planck Institute of Biochemistry in Martinsried, Germany, and the Institute of Structural Biology in Grenoble, France, used neutron beams to expand current knowledge on structure-function relations in the ion pump bacteriorhodopsin. By using isotope-labeled membranes, areas of different dynamical behavior were detected, and a functionally essential Glycolipid was localized.

A collaboration between biochemists Heiko Patzelt and Dieter Oesterhelt from Munich's Max Planck Institute of Biochemistry and biophysicists Martin Weik, Valrie Rat and Giuseppe Zaccai from the Institute of Structural Biology in Grenoble yielded new and unusual insights into the structure-function relations in the light-driven proton pump bacteriorhodopsin. Using neutron spectroscopy and diffraction experiments, which are sensitive to isotope labels, areas of differential dynamical behavior within the protein, as well as the position of functionally important lipids surrounding it, were localized. The discoveries were recently published in Molecular Cell (1998, vol. 1, 411-419) and in the Proceedings of the National Academy of Science of the USA (1998, vol. 49, 4970-4975).

Membrane proteins play key roles in the functioning of the living cell. Apart from very few exceptions, their structure-function relations, however, still remain unclear. The light-driven proton pump bacteriorhodopsin, the photosynthetic retinal-protein in the cell walls of the salt-loving microorganism Halobacterium salinarum, can be prepared in selectively isotope-labeled forms. In addition to neutron diffraction (Journal of Molecular Biology 1989, 210, 829-847) and Nuclear Magnetic Resonance (NMR) investigations (Journal of
'"/>

Contact: Dieter Oesterhelt
oesterhe@biochem.mpg.de
+49-89-8578-2386
Max-Planck-Gesellschaft
14-May-1998


Page: 1 2 3 4

Related biology news :

1. Creation of the UK Clinical Research Collaboration will boost clinical trials in UK
2. Collaboration at EMSL produces innovative mass spectrometer
3. Collaboration to use proteomics to unravel mysteries of heart disease
4. Collaboration advances potential therapy for autoimmune diseases
5. Abgenix and Chiron enter Xenomouse Technology Collaboration, targets antibody products for autoimmune disease and cancer
6. University-Industry-Government Institute Will Study Pollution Control Chemistry In A Unique Virtual Collaboration
7. US-Cuban Scientific Collaborations Jeopardized By Travel Restrictions
8. UB Study Finds No Relationship Between Male Consumption Of Lake Ontario Fish And Conception Delay
9. Jefferson Scientists Find Link Between Learning And Preventing Alzheimers
10. UI Researchers Find Possible Genetic Link Between The X Chromosome And Ovarian Cancer
11. Scientists Devise Method To Address Conflict Between Molecular Clock, Fossil Record Of Mammalian Evolution

Post Your Comments:
(Date:3/20/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/rswjb4/hand_geometry ) has announced ... Business Report" report to their offering. This ... Thousands. The report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... Annual estimates and forecasts are provided for the ...
(Date:3/19/2015)... March 19, 2015  NXT-ID, Inc. (NASDAQ: NXTD ... on the growing mobile commerce market, announces its biometric payment ... clip that aired this week on Washington DC,s ... In a segment "The Next Great Thing", host ... way to pay, and ,a really big breakthrough in mobile ...
(Date:3/17/2015)... March 17, 2015 Emotient, the leader ... today announced general availability of Emotient Analytics ... the analysis of facial expressions. The system analyzes ... content, products and services. It delivers audience response ... sentiment - as derived from facial evidence of ...
Breaking Biology News(10 mins):Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 2New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 4
(Date:4/25/2015)... (PRWEB) April 25, 2015 Join us ... 29th: Analyzing Kinase Inhibitor Residence Times using the Transcreener® ... of inhibitor residence times is increasingly being incorporated into ... can result in improved efficacy, increased therapeutic window and ... determined using immobilized ligand methods such surface plasmon resonance, ...
(Date:4/24/2015)... Top student social innovators from the ... universities, including UCSD and SDSU, will pitch their impact ... national and nonprofit companies for an opportunity to win ... Social Innovation Challenge 2015 . , The 2015 Social ... addressing a diverse range of issues including poverty, education, ...
(Date:4/24/2015)... SD and Tempe, AZ (PRWEB) April 24, 2015 ... Technology and Arizona State University (ASU) have entered into ... joint projects. , A memorandum of agreement signed by ... long distance learning, student success and other services particularly, ... resources. , “We have complementary strengths and a ...
(Date:4/24/2015)... California (PRWEB) April 24, 2015 ... key milestones in its allogeneic stem-cell product development ... to properly reflect the corporate strategic direction. , ... allogeneic (donor) adipose stem cell development program has ... of our cGMP manufacturing facility and hiring of ...
Breaking Biology Technology:BellBrook Labs Webinar: Analyzing Kinase Inhibitor Residence Times using the Transcreener® ADP Assay 25th Annual Social Innovation Challenge at University of San Diego - Students Pitch to Live Judging Panel to Take Home $75K 25th Annual Social Innovation Challenge at University of San Diego - Students Pitch to Live Judging Panel to Take Home $75K 3South Dakota Mines, Arizona State University Pave Way for Cooperative Research 2Vet-Stem, Inc. Meets New Milestones and Changes Name to VetStem Biopharma 2
Cached News: