HOME >> BIOLOGY >> NEWS
Very Fruitful Collaboration Between French And German Scientists Yields Unusual Insights Into The Structure Of Membrane Proteins

Scientists from the Max Planck Institute of Biochemistry in Martinsried, Germany, and the Institute of Structural Biology in Grenoble, France, used neutron beams to expand current knowledge on structure-function relations in the ion pump bacteriorhodopsin. By using isotope-labeled membranes, areas of different dynamical behavior were detected, and a functionally essential Glycolipid was localized.

A collaboration between biochemists Heiko Patzelt and Dieter Oesterhelt from Munich's Max Planck Institute of Biochemistry and biophysicists Martin Weik, Valrie Rat and Giuseppe Zaccai from the Institute of Structural Biology in Grenoble yielded new and unusual insights into the structure-function relations in the light-driven proton pump bacteriorhodopsin. Using neutron spectroscopy and diffraction experiments, which are sensitive to isotope labels, areas of differential dynamical behavior within the protein, as well as the position of functionally important lipids surrounding it, were localized. The discoveries were recently published in Molecular Cell (1998, vol. 1, 411-419) and in the Proceedings of the National Academy of Science of the USA (1998, vol. 49, 4970-4975).

Membrane proteins play key roles in the functioning of the living cell. Apart from very few exceptions, their structure-function relations, however, still remain unclear. The light-driven proton pump bacteriorhodopsin, the photosynthetic retinal-protein in the cell walls of the salt-loving microorganism Halobacterium salinarum, can be prepared in selectively isotope-labeled forms. In addition to neutron diffraction (Journal of Molecular Biology 1989, 210, 829-847) and Nuclear Magnetic Resonance (NMR) investigations (Journal of
'"/>

Contact: Dieter Oesterhelt
oesterhe@biochem.mpg.de
+49-89-8578-2386
Max-Planck-Gesellschaft
14-May-1998


Page: 1 2 3 4

Related biology news :

1. Creation of the UK Clinical Research Collaboration will boost clinical trials in UK
2. Collaboration at EMSL produces innovative mass spectrometer
3. Collaboration to use proteomics to unravel mysteries of heart disease
4. Collaboration advances potential therapy for autoimmune diseases
5. Abgenix and Chiron enter Xenomouse Technology Collaboration, targets antibody products for autoimmune disease and cancer
6. University-Industry-Government Institute Will Study Pollution Control Chemistry In A Unique Virtual Collaboration
7. US-Cuban Scientific Collaborations Jeopardized By Travel Restrictions
8. UB Study Finds No Relationship Between Male Consumption Of Lake Ontario Fish And Conception Delay
9. Jefferson Scientists Find Link Between Learning And Preventing Alzheimers
10. UI Researchers Find Possible Genetic Link Between The X Chromosome And Ovarian Cancer
11. Scientists Devise Method To Address Conflict Between Molecular Clock, Fossil Record Of Mammalian Evolution

Post Your Comments:
(Date:2/23/2015)... , Feb. 23, 2015 NXT-ID, Inc. (NASDAQ: ... "Company"), a biometric authentication company focused on the growing ... provisional patent 62114357 for DISTRIBUTED VOICE DIRECTED ... NXT-ID introduces a new groundbreaking payment method. Payment accounts ... account may only be accessed if both the speech ...
(Date:2/13/2015)... Feb. 13, 2015 ACT Genomics Co., ... aims to transform cancer genomic information into precision ... company has raised US$ 8 million in the its ... Taipei, Taiwan , ACT Genomics ... With the aim to implement next generation sequencing ...
(Date:2/11/2015)... According to a ... Product (Cards and Readers, Biometrics, Controllers, Management Software), ... Healthcare, Education) and By Geography - Global Forecast and Analysis to ... Control Market is expected to reach $10.4 ... of 10.6% between 2014 and 2020. ...
Breaking Biology News(10 mins):NXT-ID Patents Voice Directed Payments 2NXT-ID Patents Voice Directed Payments 3ACT Genomics Raises $8 Million in its First Private Funding Round 2Access Control Market Worth $10.4 Billion by 2020 2Access Control Market Worth $10.4 Billion by 2020 3Access Control Market Worth $10.4 Billion by 2020 4
(Date:2/26/2015)... 2015 The Movement for Indefinite Life ... life extension technologies and awareness. The event is taking ... on March 21st 2015, in a live Google Hangout ... Schulke, Founder of MILE, says, “Our lives are in ... Movement for Indefinite Life Extension is raising awareness about ...
(Date:2/26/2015)... VIEW, Calif. , Feb. 26, 2015 The ... navigate this ever-changing arena, Frost & Sullivan will host its ... & Sullivan Executive MindXchange , March 8 to 10, at ... San Diego, Calif. This event is ... connected healthcare leaders to discuss industry disruptions and how to ...
(Date:2/26/2015)... 2015 Already well respected for accuracy, ... expanding its Length Gauge offerings with new variants of ... , Specifically, HEIDENHAIN’s pencil probe-style SPECTO length gauge series ... Two new 1Vpp, 12mm stroke length variants of the ... is a variant with a weak spring, 0.4N of ...
(Date:2/26/2015)... According to a new market report published by ... (Corn, Soybean, Cotton and Others), Synthetic Biology-Enabled Products and ... and Forecast, 2013 – 2019,”the global agricultural biotechnology market ... is expected to reach USD 28,694.1 million by 2019, ... 2019. , Demand for food production has increased ...
Breaking Biology Technology:Indefinite Life Extension Activists Organize Online Demonstration 2Indefinite Life Extension Activists Organize Online Demonstration 3Embrace the Future of Medical Technologies with Frost & Sullivan 2Embrace the Future of Medical Technologies with Frost & Sullivan 3Accuracy and Versatile Gauging Go Hand in Hand at HEIDENHAIN 2Global Agricultural Biotechnology Market is Expected to Reach USD 28,694.1 Million in 2019 : Transparency Market Research 2Global Agricultural Biotechnology Market is Expected to Reach USD 28,694.1 Million in 2019 : Transparency Market Research 3
Cached News: