HOME >> BIOLOGY >> NEWS
Very Fruitful Collaboration Between French And German Scientists Yields Unusual Insights Into The Structure Of Membrane Proteins

Scientists from the Max Planck Institute of Biochemistry in Martinsried, Germany, and the Institute of Structural Biology in Grenoble, France, used neutron beams to expand current knowledge on structure-function relations in the ion pump bacteriorhodopsin. By using isotope-labeled membranes, areas of different dynamical behavior were detected, and a functionally essential Glycolipid was localized.

A collaboration between biochemists Heiko Patzelt and Dieter Oesterhelt from Munich's Max Planck Institute of Biochemistry and biophysicists Martin Weik, Valrie Rat and Giuseppe Zaccai from the Institute of Structural Biology in Grenoble yielded new and unusual insights into the structure-function relations in the light-driven proton pump bacteriorhodopsin. Using neutron spectroscopy and diffraction experiments, which are sensitive to isotope labels, areas of differential dynamical behavior within the protein, as well as the position of functionally important lipids surrounding it, were localized. The discoveries were recently published in Molecular Cell (1998, vol. 1, 411-419) and in the Proceedings of the National Academy of Science of the USA (1998, vol. 49, 4970-4975).

Membrane proteins play key roles in the functioning of the living cell. Apart from very few exceptions, their structure-function relations, however, still remain unclear. The light-driven proton pump bacteriorhodopsin, the photosynthetic retinal-protein in the cell walls of the salt-loving microorganism Halobacterium salinarum, can be prepared in selectively isotope-labeled forms. In addition to neutron diffraction (Journal of Molecular Biology 1989, 210, 829-847) and Nuclear Magnetic Resonance (NMR) investigations (Journal of
'"/>

Contact: Dieter Oesterhelt
oesterhe@biochem.mpg.de
+49-89-8578-2386
Max-Planck-Gesellschaft
14-May-1998


Page: 1 2 3 4

Related biology news :

1. Creation of the UK Clinical Research Collaboration will boost clinical trials in UK
2. Collaboration at EMSL produces innovative mass spectrometer
3. Collaboration to use proteomics to unravel mysteries of heart disease
4. Collaboration advances potential therapy for autoimmune diseases
5. Abgenix and Chiron enter Xenomouse Technology Collaboration, targets antibody products for autoimmune disease and cancer
6. University-Industry-Government Institute Will Study Pollution Control Chemistry In A Unique Virtual Collaboration
7. US-Cuban Scientific Collaborations Jeopardized By Travel Restrictions
8. UB Study Finds No Relationship Between Male Consumption Of Lake Ontario Fish And Conception Delay
9. Jefferson Scientists Find Link Between Learning And Preventing Alzheimers
10. UI Researchers Find Possible Genetic Link Between The X Chromosome And Ovarian Cancer
11. Scientists Devise Method To Address Conflict Between Molecular Clock, Fossil Record Of Mammalian Evolution

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/21/2016)... , June 21, 2016 NuData ... the new role of principal product architect and ... the director of customer development. Both will report ... technical officer. The moves reflect NuData,s strategic growth ... response to high customer demand and customer focus ...
(Date:6/9/2016)... , June 9, 2016 ... Police deploy Teleste,s video security solution to ensure the safety ... France during the major tournament Teleste, ... communications systems and services, announced today that its video security ... to back up public safety across the country. ...
(Date:6/2/2016)... , June 2, 2016 ... Manned Platforms, Unmanned Systems, Physical Infrastructure, Support & Other ... provider visiongain offers comprehensive analysis of the ... this market will generate revenues of $17.98 billion in ... acquired DVTEL Inc, a leader in software and hardware ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... CA (PRWEB) , ... June 27, 2016 , ... ... for clinical trials, announced today the Clinical Reach Virtual Patient Encounter CONSULT ... care circle with the physician and clinical trial team. , Using the CONSULT module, ...
(Date:6/24/2016)... , June 24, 2016  Regular discussions on a range ... place between the two entities said Poloz. Speaking ... Ottawa , he pointed to the country,s inflation ... federal government. "In ... "Both institutions have common economic goals, why not sit down ...
(Date:6/23/2016)... ... June 23, 2016 , ... UAS ... the launch of their brand, UP4™ Probiotics, into Target stores nationwide. The company, ... proud to add Target to its list of well-respected retailers. This list includes ...
(Date:6/23/2016)... ... 2016 , ... Charm Sciences, Inc. is pleased to announce ... Research Institute approval 061601. , “This is another AOAC-RI approval of the Peel ... President of Regulatory and Industrial Affairs. “The Peel Plate methods perform comparably to ...
Breaking Biology Technology:
Cached News: