Vesicle Chemistry: A New Way To Get Life-Like Reactions

The chemistry of life is different from chemistry at large, in part because it takes place in tiny containers called cells.

So chemists at Stanford University, working with researchers at the University of Göteborg in Sweden and Pomona College in Claremont, Calif., have found a way to make tiny, cell-sized containers, called vesicles, and use them to study the chemical reactions of biological molecules in an environment that closely mimics the interior of a living cell.

"We now have the world's smallest test tubes," says Richard N. Zare, the Marguerite Blake Wilbur Professor of Chemistry at Stanford, who headed the research effort reported in the March 19 issue of the journal Science. The ability to study chemical reactions in cell-like containers has a number of possible applications. Among them are:

  • Investigating important parts of the cell's metabolism including accumulation and release of neurotransmitters and synthesis of proteins;
  • Examining the biochemistry of cells infected with pathogens;
  • Delivering drugs and genes to single cells.

"In the past, when studying the chemistry of life, we had two basic choices: to experiment 'in vivo' -- in living cells -- or 'in vitro' -- in glass containers. Now we have a third choice, that is in-between the two, but much closer to 'in vivo,'" Zare says of the vesicle approach.

Producing this new form of micro-chemistry begins by creating tiny vesicles that contain a single chemical compound. The researchers found that they can reliably create these membrane sacs in a few minutes. They do so by floating a layer of artificial membrane on the surface of a mixture of a desired chemical and a suitable solvent, such as a mixture of alcohol and water, and then causing the solvent to boil away by lowering the air pressure above the membrane. As the water evaporates, it leaves behind vesicles filled with the desired chemical that range in size from 50 microns to 50 nanometers in

Contact: David F. Salisbury
Stanford University

Page: 1 2 3

Related biology news :

1. Substance Abuse May Curb Bodys Stress Reactions
2. Bakers Yeast Causes Chemical Reactions And Sweet Smelling Labs
3. Common Food Dye Can Cause Severe Allergic Reactions
4. Popular Cure-All Tea Can Cause Toxic Reactions
5. New Way To Drive Chemical Reactions: Collision Of Liquids At High Speed

Post Your Comments:

(Date:7/1/2020)... ... July 01, 2020 , ... Catalent, ... the purchase of Teva-Takeda Pharmaceuticals’ packaging facility in Minakuchi, located in the Shiga ... supply facility located in Kakegawa, the new 60,000-square-foot facility will provide customers with ...
(Date:6/25/2020)... ... June 24, 2020 , ... ... software-driven clinical data services that accelerate drug development, is collaborating with Karyopharm Therapeutics ... inhibitor, in hospitalized patients with severe COVID-19. This is the first study of ...
(Date:6/23/2020)... ... 23, 2020 , ... Rigaku Corporation , a global ... a series of TOPIQ webinars, which will cover the Transferable Aspherical Atom Model ... response to social distancing measures that resulted in postponements and cancelations of global ...
Breaking Biology News(10 mins):
(Date:7/10/2020)... ... 2020 , ... Sentien Biotechnologies, Inc., a clinical-stage biotechnology company ... Nissenson, M.D., F.A.C.P., as its Chief Medical Officer. Dr. Nissenson will join ... Dr. Nissenson serves as an Emeritus Professor of Medicine at the David ...
(Date:7/7/2020)... BOSTON (PRWEB) , ... July 06, 2020 , ... ... Innovative Practices Awards. Entries from Roche, Eli Lilly, Bristol-Myers Squibb, the University of ... Since 2003, Bio-IT World has hosted an elite awards program, highlighting outstanding examples ...
(Date:7/1/2020)... GREEN, Ohio (PRWEB) , ... June 29, 2020 ... ... that offers access to competitively procured purchasing contracts to its membership, recently named ... to provide TIPS members with the opportunity to purchase ergonomic seating, cafeteria tables, ...
(Date:6/28/2020)... ... June 25, 2020 , ... The Indoor Lab, a leading provider of sensor ... of all types to ensure cleanliness, distancing and occupancy with its patent pending WipeAway™ ... enabled business will provide a health performance index system that scores all aspects of ...
Breaking Biology Technology:
Cached News: