HOME >> BIOLOGY >> NEWS
Vion's TAPET® administered to first patients in Phase I human intratumoral safety trial at the Cleveland Clinic Foundation

alization of cancer treatment technologies. Vion's product portfolio consists of TAPET, a drug delivery platform, and three cancer therapeutics (Promycin, Triapine and Sulfonyl Hydrazine Prodrugs). TAPET has been shown in preclinical models to effectively deliver anticancer agents while having a minimal toxic effect on healthy normal tissues. TAPET uses genetically altered strains of Salmonella as a bacterial vector, or vehicle, for delivering cancer fighting drugs preferentially to solid tumors. Promycin, which attacks oxygen depleted cancer cells, is currently being evaluated with radiation in a multicenter Phase III clinical trial for the treatment of head and neck cancer. Triapine, which is designed to prevent the replication of tumor cells by blocking a critical step in the synthesis of DNA, is currently being evaluated for its safety in a Phase I clinical trial. Sulfonyl Hydrazine Prodrugs, compounds that are designed to be converted to unique potent, alkylating agents, are currently being evaluated in preclinical studies.


'"/>

Contact: Sue Yeoh
syeoh@cpronline.com
201-641-2408 x43
Vion Pharmaceuticals, Inc.
8-Dec-1999


Page: 1 2

Related biology news :

1. Vions TAPET Organisms Demonstrate Reduced Virulence, Increased Safety While Retaining Ability To Specifically Target Tumors
2. New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
3. Newly identified master gene key in babys first breath
4. The book opens on the first tree genome
5. DuPont developing new protective suits for military, first responders
6. Joslin Diabetes Center adds first affiliate in California at Irvine Medical Center
7. Maine-based biophysics institute gets funding for first US-based 4Pi nanoscale microscope
8. Veterinarians discover first known case of canine distemper in a wild tiger
9. Study reveals first genetic step necessary for prostate cancer growth
10. The first engineering of cell surfaces in living animals
11. Infant rats eagerly accept high concentrations of alcohol upon first exposure

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/4/2019)... ... , ... Lajollacooks4u is delighted to announce it has been named as one ... given only to businesses that have achieved consistently outstanding traveler reviews on TripAdvisor, as ... To qualify for the Certificate of Excellence –- an award that only 10 percent ...
(Date:5/31/2019)... ... May 30, 2019 , ... Researchers from Ambry Genetics ... significant differences in the prevalence of hereditary genetic mutations, also called germline mutations, ... women. Results will be presented at the 2019 American Society of Clinical Oncology ...
(Date:5/26/2019)... ... ... Zolgensma (Novartis, AveXis), an AAV-delivered gene therapy used to treat spinal muscular atrophy ... by the Food and Drug Administration today. , The treatment is now ... United States and the second-ever approved treatment for SMA. , FDA granted priority review ...
Breaking Biology News(10 mins):
(Date:6/18/2019)... ... ... Personalized Stem Cells, Inc (“PSC”), a human adipose-derived stem cell ... of a person’s own adipose-derived stem cells to treat their osteoarthritis. The first clinical ... IND is the first of several planned clinical trials which will enable qualified PSC-enrolled ...
(Date:6/11/2019)... ... June 11, 2019 , ... ... Clinic, a national leader in opioid treatment, announced today they are partnering to ... , Mytonomy recently deployed its virtual care platform at the Mayo Clinic to ...
(Date:5/31/2019)... City, California (PRWEB) , ... ... ... allowance of our patent applications from the USPTO providing proprietary interest to ... AND METHOD FOR SLEEP DISORDER DIAGNOSIS AND TREATMENT… extends Somnology’s IP rights ...
(Date:5/21/2019)... ABABA, Ethiopia (PRWEB) , ... May 21, 2019 ... ... für Brauerei in Berlin (VLB) today officially opened the inaugural Africa Brewing Conference ... brewing and malting industry in Africa. The event, which is supported through a ...
Breaking Biology Technology:
Cached News: